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The map label for this gene is adhB [H]

Identifier: 226948703

GI number: 226948703

Start: 1666555

End: 1667754

Strand: Direct

Name: adhB [H]

Synonym: CLM_1601

Alternate gene names: 226948703

Gene position: 1666555-1667754 (Clockwise)

Preceding gene: 226948701

Following gene: 226948704

Centisome position: 40.11

GC content: 33.42

Gene sequence:

>1200_bases
ATGTGGGAATCTAAAATGGCTATAAATGAGATAAGAGAGATAAGATCCAAGACCACTGTTTATTTAGGGGTAGGAGCAAT
AGAAAAAATATATGATATAGCATCTAATTTGAAAAATATGAATATAGATAAGGTACTTATTGTCACAGGAAGAGGGGCTT
ACAAAAAAACTGGGGCTTGGGAATATGTTGAAAAAGCTTTGGAGAAGGAAAATATAGCCTATATTTTATATAATGAAGTT
ACACCAAATCCAACTGTAGATCAAGTAGACGAGGCTGCTAGAATGGGAAATGAATTAGGTGCAAAGGCGGTAATAGGTAT
AGGAGGAGGAAGTCCTATAGATGCAGCTAAAAGTGTAGCAATACTTTTAGAATATAAAGATAAAACTGCAAGGGATATAT
ATGAATTTAAATTTACCCCAGAAAAAGCATCTCCAGTTATTGCAATAAATTTAACTCATGGAACAGGCACAGAAGGAGAT
AGATTTGCAGTAGTCAGTATTCCAGAAAAAGAATACAAGCCAGCCATAGCTTATGATTGTATATATCCTTTATATGCTAT
AGATGACCCACAACTTATGGTTAAACTACCAATACACCAAACTTGCTATGTATCAGTGGACGCTATAAATCATGTAGTAG
AGGCTTCCACAAGTAAAGTAGCAAATCCATATACCATATTATTAGCAAAGGAAACCGTGAGACTAGTTTCTAGATATTTG
CCACAGGCATTGCAACATCCAGGGGATCTAACAGCTAGATATTATTTAACATATGCTTCTTTAATTGCAGGTATATGTTT
TGATAATGGATTACTTCATTTTACTCATGCTTTAGAACATCCATTAAGTGGAGTGAAACCAGATTTATCTCATGGTTTAG
GATTAGGAATATTATTACCTGCTGTAATAAAGGAAATATATCCATCAGTATCTGAAGTTTTAGCAGATATTTTATCACCA
ATAGTTTGTGGGTTGGAAGGAAATCCGGGAGAAGCTGAAATAGCAGCTAAAGGTATAGAAAAATGGTTATATAGTATAGG
TATTACAGAAAAATTAACAGACTTAGGATTTAAAGAAAATGATGTGGAAAAATTGACAAAGTTAGCTTTTGAAACACCAA
GCTTAGACTTATTGTTAAGTATGGCTCCAATAGATGCAGATGAAAAGGTCGTTAGTAATATATTTAGAAATTCTCTCTAA

Upstream 100 bases:

>100_bases
AAACTATTGTGTTTTGTTAAAAAAATAACTATAATATAAATATGATAGTCTATTTACATTATTTATATAATCTTATATAA
ATTTAAGGGGGTATTTATGA

Downstream 100 bases:

>100_bases
ATTTAATATAAATAGTAATTATAGAAAAGCTTTTATATAGGTTATATGAAAGCAAAAAAATTAATTTAAAATAAAACTAC
CTAAAAGATGATTAATATGG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAWEYVEKALEKENIAYILYNEV
TPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVAILLEYKDKTARDIYEFKFTPEKASPVIAINLTHGTGTEGD
RFAVVSIPEKEYKPAIAYDCIYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVANPYTILLAKETVRLVSRYL
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLPAVIKEIYPSVSEVLADILSP
IVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKENDVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL

Sequences:

>Translated_399_residues
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAWEYVEKALEKENIAYILYNEV
TPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVAILLEYKDKTARDIYEFKFTPEKASPVIAINLTHGTGTEGD
RFAVVSIPEKEYKPAIAYDCIYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVANPYTILLAKETVRLVSRYL
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLPAVIKEIYPSVSEVLADILSP
IVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKENDVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL
>Mature_399_residues
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAWEYVEKALEKENIAYILYNEV
TPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVAILLEYKDKTARDIYEFKFTPEKASPVIAINLTHGTGTEGD
RFAVVSIPEKEYKPAIAYDCIYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVANPYTILLAKETVRLVSRYL
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLPAVIKEIYPSVSEVLADILSP
IVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKENDVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=411, Percent_Identity=23.6009732360097, Blast_Score=102, Evalue=9e-22,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=30.7894736842105, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87082107, Length=349, Percent_Identity=28.6532951289398, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1787493, Length=365, Percent_Identity=29.5890410958904, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789163, Length=380, Percent_Identity=27.1052631578947, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789386, Length=375, Percent_Identity=26.1333333333333, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=428, Percent_Identity=25.7009345794392, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321181, Length=372, Percent_Identity=31.989247311828, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24657991, Length=423, Percent_Identity=24.3498817966903, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43715; Mature: 43715

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAW
CCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
EYVEKALEKENIAYILYNEVTPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVA
HHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCHHCCCEEEEECCCCCCCHHHCCEE
ILLEYKDKTARDIYEFKFTPEKASPVIAINLTHGTGTEGDRFAVVSIPEKEYKPAIAYDC
EEEEECCCCHHHHEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCHHHCCCCEEHHH
IYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVANPYTILLAKETVRLVSRYL
HCCEEECCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHH
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLP
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHH
AVIKEIYPSVSEVLADILSPIVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKEN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
DVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL
HHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MWESKMAINEIREIRSKTTVYLGVGAIEKIYDIASNLKNMNIDKVLIVTGRGAYKKTGAW
CCCCHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCH
EYVEKALEKENIAYILYNEVTPNPTVDQVDEAARMGNELGAKAVIGIGGGSPIDAAKSVA
HHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHCCHHCCCEEEEECCCCCCCHHHCCEE
ILLEYKDKTARDIYEFKFTPEKASPVIAINLTHGTGTEGDRFAVVSIPEKEYKPAIAYDC
EEEEECCCCHHHHEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCHHHCCCCEEHHH
IYPLYAIDDPQLMVKLPIHQTCYVSVDAINHVVEASTSKVANPYTILLAKETVRLVSRYL
HCCEEECCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHH
PQALQHPGDLTARYYLTYASLIAGICFDNGLLHFTHALEHPLSGVKPDLSHGLGLGILLP
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHHH
AVIKEIYPSVSEVLADILSPIVCGLEGNPGEAEIAAKGIEKWLYSIGITEKLTDLGFKEN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
DVEKLTKLAFETPSLDLLLSMAPIDADEKVVSNIFRNSL
HHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]