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The map label for this gene is walR [H]

Identifier: 226948577

GI number: 226948577

Start: 1527461

End: 1528153

Strand: Direct

Name: walR [H]

Synonym: CLM_1469

Alternate gene names: 226948577

Gene position: 1527461-1528153 (Clockwise)

Preceding gene: 226948576

Following gene: 226948578

Centisome position: 36.76

GC content: 26.41

Gene sequence:

>693_bases
ATGAAAAGTATATTGCTTGTAGAGGATAATATGTCATTAAATAGAGGAATACAATTTTCTCTTATGAAGGAAGGATATAA
TGTTATAGCTACAGATAGTATAAAAGAATCCCAGCAAAAGCTTAATAAAGAAAAAGTAGATTTAATAATATTGGATATTA
ATTTACCAGATGGAAATGGGTTCGATTATTGCTTAGATATTAGAAAAACTAGTAATATTCCCATAATATTTTTAACAGCT
CTTGATTCTGAAATAGATGTGGTAAATGGTTTGGATATGGGAGCAGATGATTATATAACTAAACCTTTTAGATTAAGAGA
GCTTATTTCAAGAGTTAATGCCATAATAAGGAGGACATCAAATGATTGCGACTTTAATATAATTCAGTCAAAGGATATAG
TTTTTTATATTAATGAAATGAAGATTGAAAAGCATGGAAAAGAAATTTTTTTAAGTAAGACAGAATTAAAATTACTTCAA
TATTTTATGAAAAATTATCAAAAGATATTATCAAAAGAGCAAATAATAGAAAACTTATGGAATATAGATGGAGAATTTAT
TAATGAAAATACTGTAGCAGTAAATATAAGAAGGATAAGAGAAAAAATAGAAGAAGTGCCATCAAAACCTGAATATATAC
AAACTATCAGAGGGATAGGTTATGTTTGGAAAGAAGGATGTGTTAGGAAATGA

Upstream 100 bases:

>100_bases
TATTACATTTATAACTGTATTTGATATATTATTTATGTAGAGTATATCTAGAATATTAAAATAAAGCTTATTTAGAGAAA
TTAATTTAAGAGGTGGAATA

Downstream 100 bases:

>100_bases
ATGAAAATATATCCAAAGAACCTATTATTAGAAAAACCATATTTTTATTCATAGGTTTAACGATTGTTATGTTATTTTTT
CAAGGTTTCTATTTTTACAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKSILLVEDNMSLNRGIQFSLMKEGYNVIATDSIKESQQKLNKEKVDLIILDINLPDGNGFDYCLDIRKTSNIPIIFLTA
LDSEIDVVNGLDMGADDYITKPFRLRELISRVNAIIRRTSNDCDFNIIQSKDIVFYINEMKIEKHGKEIFLSKTELKLLQ
YFMKNYQKILSKEQIIENLWNIDGEFINENTVAVNIRRIREKIEEVPSKPEYIQTIRGIGYVWKEGCVRK

Sequences:

>Translated_230_residues
MKSILLVEDNMSLNRGIQFSLMKEGYNVIATDSIKESQQKLNKEKVDLIILDINLPDGNGFDYCLDIRKTSNIPIIFLTA
LDSEIDVVNGLDMGADDYITKPFRLRELISRVNAIIRRTSNDCDFNIIQSKDIVFYINEMKIEKHGKEIFLSKTELKLLQ
YFMKNYQKILSKEQIIENLWNIDGEFINENTVAVNIRRIREKIEEVPSKPEYIQTIRGIGYVWKEGCVRK
>Mature_230_residues
MKSILLVEDNMSLNRGIQFSLMKEGYNVIATDSIKESQQKLNKEKVDLIILDINLPDGNGFDYCLDIRKTSNIPIIFLTA
LDSEIDVVNGLDMGADDYITKPFRLRELISRVNAIIRRTSNDCDFNIIQSKDIVFYINEMKIEKHGKEIFLSKTELKLLQ
YFMKNYQKILSKEQIIENLWNIDGEFINENTVAVNIRRIREKIEEVPSKPEYIQTIRGIGYVWKEGCVRK

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.7354260089686, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=30.6306306306306, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=32.8947368421053, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=33.1858407079646, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=32.2727272727273, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=31.140350877193, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=32.7272727272727, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=32.7354260089686, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=33.6283185840708, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=33.0275229357798, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=30.9417040358744, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=31.1688311688312, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=27.2340425531915, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26790; Mature: 26790

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILLVEDNMSLNRGIQFSLMKEGYNVIATDSIKESQQKLNKEKVDLIILDINLPDGNG
CCCEEEEECCCCCCCCEEEEEECCCCCEEEECHHHHHHHHCCCCCEEEEEEEEECCCCCC
FDYCLDIRKTSNIPIIFLTALDSEIDVVNGLDMGADDYITKPFRLRELISRVNAIIRRTS
CEEEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCC
NDCDFNIIQSKDIVFYINEMKIEKHGKEIFLSKTELKLLQYFMKNYQKILSKEQIIENLW
CCCCEEEEECCCEEEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIDGEFINENTVAVNIRRIREKIEEVPSKPEYIQTIRGIGYVWKEGCVRK
CCCCCEECCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKSILLVEDNMSLNRGIQFSLMKEGYNVIATDSIKESQQKLNKEKVDLIILDINLPDGNG
CCCEEEEECCCCCCCCEEEEEECCCCCEEEECHHHHHHHHCCCCCEEEEEEEEECCCCCC
FDYCLDIRKTSNIPIIFLTALDSEIDVVNGLDMGADDYITKPFRLRELISRVNAIIRRTS
CEEEEEEEECCCCCEEEEEECCCCCCEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCC
NDCDFNIIQSKDIVFYINEMKIEKHGKEIFLSKTELKLLQYFMKNYQKILSKEQIIENLW
CCCCEEEEECCCEEEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIDGEFINENTVAVNIRRIREKIEEVPSKPEYIQTIRGIGYVWKEGCVRK
CCCCCEECCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA