Click here to switch to the map view.

The map label for this gene is fucA [H]

Identifier: 226948537

GI number: 226948537

Start: 1483790

End: 1484437

Strand: Direct

Name: fucA [H]

Synonym: CLM_1429

Alternate gene names: 226948537

Gene position: 1483790-1484437 (Clockwise)

Preceding gene: 226948536

Following gene: 226948538

Centisome position: 35.71

GC content: 30.25

Gene sequence:

>648_bases
TTGAATAATGAAACGTATTTAAGGTTACAAATTGTAGAAGTAGGAAAAAGACTTCAACAAAGATTTTTTGTAGCTTCAAA
TGATGGAAATATAAGTGCTAAACTTGATGAAAATACTATATTGATTACGCCTACAGGCGTTAATAAAGGAGAAGTAACTC
CAGATCAAATAATAAAAGTAGATAGAGAAGGAAATGTTATAGAAGGTCATATGAAAGTTACATCTGAAATAAAAATGCAT
TTAGCTGTTTATAATATGAGAGAAGATGTAAAAGCTATAGTTCATGCCCATCCACCAGCATCCACAGCTTTTTCAGTATC
AAAAGAAAAACTAGATGATCCTGTTATTCTTCCAGAAGCAGTTTTTTCATTAGGGAAAATAGGATATTGTGAATATGGAA
CTCCTTCTACTGATGAGGTTCCAAAAGCTGTAGAAAAAGAAATTCCATATAGTGATGTACTTTTATTATCTAACCATGGA
GCTCTTACAGTAGGTACAGATGTAATGCAGGCTTATTACAGAATGGAAAATTTAGAAATGGTTTCAAAGGTAACTATTTA
TTCAAAAATGATAGGAAATATAAAAACTTTAAATGAACTACAAGTTGAGAAATTAAATAAAGTAAAAGAAGAAAAAGGTT
GGGGGTAA

Upstream 100 bases:

>100_bases
ATAAAAAAGTCCTTTTCAGATGTTCAAGTATTACATGAAATAAATAATTGGGGGATTTTATCCCCAAATTTATTAATCAC
TTAGTAAAGAGGGTGACAAT

Downstream 100 bases:

>100_bases
ATTATAGTTACCACCTATATAGCTTTTTAATAATTAGGTAAATATGCCTGTAATAGAACCATTATGTTTAAATTTTGTAA
AAAGTGGTGTCATGTACAAG

Product: aldolase, class II, AraD/FucA subfamily

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMH
LAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAVEKEIPYSDVLLLSNHG
ALTVGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG

Sequences:

>Translated_215_residues
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMH
LAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAVEKEIPYSDVLLLSNHG
ALTVGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG
>Mature_215_residues
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKVDREGNVIEGHMKVTSEIKMH
LAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEAVFSLGKIGYCEYGTPSTDEVPKAVEKEIPYSDVLLLSNHG
ALTVGTDVMQAYYRMENLEMVSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG

Specific function: Catalyzes the reversible aldol cleavage of L-fuculose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=157, Percent_Identity=34.3949044585987, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI29826323, Length=157, Percent_Identity=34.3949044585987, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI29826321, Length=157, Percent_Identity=34.3949044585987, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI29826319, Length=157, Percent_Identity=34.3949044585987, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI89276787, Length=210, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI297307160, Length=210, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI9257190, Length=210, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI297307158, Length=210, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI9257192, Length=210, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789094, Length=185, Percent_Identity=29.1891891891892, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789164, Length=186, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533218, Length=193, Percent_Identity=27.4611398963731, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115533216, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 24010; Mature: 24010

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKV
CCCCEEEEEEHHHHHHHHHHHEEEECCCCCEEEEECCCEEEEEECCCCCCCCCHHHHEEE
DREGNVIEGHMKVTSEIKMHLAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEA
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEECHHH
VFSLGKIGYCEYGTPSTDEVPKAVEKEIPYSDVLLLSNHGALTVGTDVMQAYYRMENLEM
HHHHCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEECHHHHHHHHHHHHHHH
VSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNETYLRLQIVEVGKRLQQRFFVASNDGNISAKLDENTILITPTGVNKGEVTPDQIIKV
CCCCEEEEEEHHHHHHHHHHHEEEECCCCCEEEEECCCEEEEEECCCCCCCCCHHHHEEE
DREGNVIEGHMKVTSEIKMHLAVYNMREDVKAIVHAHPPASTAFSVSKEKLDDPVILPEA
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCEECHHH
VFSLGKIGYCEYGTPSTDEVPKAVEKEIPYSDVLLLSNHGALTVGTDVMQAYYRMENLEM
HHHHCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCEEECHHHHHHHHHHHHHHH
VSKVTIYSKMIGNIKTLNELQVEKLNKVKEEKGWG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA