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The map label for this gene is resE [H]

Identifier: 226948394

GI number: 226948394

Start: 1331081

End: 1332514

Strand: Direct

Name: resE [H]

Synonym: CLM_1278

Alternate gene names: 226948394

Gene position: 1331081-1332514 (Clockwise)

Preceding gene: 226948393

Following gene: 226948396

Centisome position: 32.03

GC content: 21.62

Gene sequence:

>1434_bases
ATGGAAAATATAAGTACTGTAATTATTAAAGAACAGCAGGAAGTTATAAAGAAATTTTTACCCATAAGATTTATATTAAT
TAACGCAGTAATGGTTTTTATTTATGTAATTTATGTTGAATCAGATTTAAAATCTTTTTGTATTTTTAATATTGCAATGG
TAGAGGGAATAATATTCAATAATATGTTGTATGGATTTTCTAGTAGAGATATGAAAACTTTTAAAAACAAATTTAATAGT
AAGTATAATAATAAAACAAAAATATATAAAAATTTTATTAATAATATTATTTCGCCTATAATAATATTAAAAGATGAAAA
AATTTATTTTATGAATGATGAAGCTAAAAAATTTATAAAAATTAAAAAGAACATAAATTTTAATAATATAAATATATATG
ATTATTTAGAAGAAAAATTTTATAAAGAAGGATTATTAAAAATAGATAATATCAAAAATTCTACAGGAATTACCTATTTA
AATGAAAAAATTATTTTAAAAAATGGAGAAATATTAAAGGTGGATTTAAGATGCTTTGTTTTAAATTTAAATGACGAAGA
GTTTGTAAGTATATCTATTAAGAACAATGTCTTATTACAAGAAAATAAAAAATTATATGAAGAGCTAGAAAAAAACAAAG
TAGAACATAGACAAAGAGCTGAATTTTATGCTAATATATCACATGATTTAAAAACACCTATAAATATTATATATTCTGCT
ATTCAGGTTATGAATATGGCTTTAAACAATAAGAAGATAGATACCATTGAAAAATATATTGGAGTAATAAAACAAAATTG
TTACAGACTTTTAAGACTTGTAAATAATATAGTTAACACCAATAAGATTGAATCCGGATGTTGTAAAATTAAATTAAATA
ATAATAATATAGTTAGTTTAGTTGAAGACATAGTTACATCTGTTTCTACATATGTTGAGAATAATGATATGGATATAATA
TTTGATACAGATACAGAAGAAAAAATTATAGCTTGTGATAAGGATATGATAGAAAGAGTTGTATTAAATCTTATATCAAA
TTCTGTTAAATATAAACAAAGCGGAAAAGGAAGTATACAAGTTACTGTACAAGATAAAGAGGATAGAGTTATTGTTTCTG
TTAAAGATAATGGTATAGGAATACCTGAAAATATACAAAAGAATGTGTTTAATAGATTTGTACAATCAAATAGAAAAGAA
TATGATTTAACAACTTGTAGTAGTGGTATAGGACTTGCTCTAGTTAAATCTATAATTGATATGCATGATGGAAATATTCA
AATAAACAGTAGAGAAAATAAAGGCACAGAAATAATCTTTGAACTTCCTTCTAGGAAGGTTAAAGAAAATGAGAAATGTA
AGGAAATATATACTAAAAATATAGGAAAGAATGTAAAAATTGAATTTCCAGAAATATATGATAGTGCTATTTGA

Upstream 100 bases:

>100_bases
TATTTTAAATTTTAAAACCAATAAAAGGAAAATAATAGAAGTAGTTGAATTATTTATATATAAAGTAAAATTATGCATAT
ATTAAAAGGGGAGTGGGGAA

Downstream 100 bases:

>100_bases
ATAAAGACTTTAAAAGAGTTGTTTTTAGTGATAAAGAGGGCGTTTCAAAATTAAATATATTTTGAAACACCTTCCTTTTA
TTATCTTATCATATAAATTG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MENISTVIIKEQQEVIKKFLPIRFILINAVMVFIYVIYVESDLKSFCIFNIAMVEGIIFNNMLYGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLNLNDEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALNNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMDII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQVTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI

Sequences:

>Translated_477_residues
MENISTVIIKEQQEVIKKFLPIRFILINAVMVFIYVIYVESDLKSFCIFNIAMVEGIIFNNMLYGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLNLNDEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALNNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMDII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQVTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
>Mature_477_residues
MENISTVIIKEQQEVIKKFLPIRFILINAVMVFIYVIYVESDLKSFCIFNIAMVEGIIFNNMLYGFSSRDMKTFKNKFNS
KYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIKIKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYL
NEKIILKNGEILKVDLRCFVLNLNDEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
IQVMNMALNNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSLVEDIVTSVSTYVENNDMDII
FDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQVTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKE
YDLTTCSSGIGLALVKSIIDMHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=26.6932270916335, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=28.3261802575107, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=23.5537190082645, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790300, Length=288, Percent_Identity=25.6944444444444, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25.3968253968254, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=25.9911894273128, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=22.7642276422764, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=24.1803278688525, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=23.1660231660232, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=24.4725738396624, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=23.9316239316239, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=23.1075697211155, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=278, Percent_Identity=26.978417266187, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=243, Percent_Identity=22.6337448559671, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55394; Mature: 55394

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENISTVIIKEQQEVIKKFLPIRFILINAVMVFIYVIYVESDLKSFCIFNIAMVEGIIFN
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NMLYGFSSRDMKTFKNKFNSKYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIK
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCHHHHHHH
IKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYLNEKIILKNGEILKVDLRCFV
HCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCEEEECCEEEEECCCEEEEEEEEEE
LNLNDEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IQVMNMALNNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
VEDIVTSVSTYVENNDMDIIFDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEE
VTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKEYDLTTCSSGIGLALVKSIID
EEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
MHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
CCCCCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHCCCC
>Mature Secondary Structure
MENISTVIIKEQQEVIKKFLPIRFILINAVMVFIYVIYVESDLKSFCIFNIAMVEGIIFN
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NMLYGFSSRDMKTFKNKFNSKYNNKTKIYKNFINNIISPIIILKDEKIYFMNDEAKKFIK
HHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCEEEEECCHHHHHHH
IKKNINFNNINIYDYLEEKFYKEGLLKIDNIKNSTGITYLNEKIILKNGEILKVDLRCFV
HCCCCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCEEEECCEEEEECCCEEEEEEEEEE
LNLNDEEFVSISIKNNVLLQENKKLYEELEKNKVEHRQRAEFYANISHDLKTPINIIYSA
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
IQVMNMALNNKKIDTIEKYIGVIKQNCYRLLRLVNNIVNTNKIESGCCKIKLNNNNIVSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHH
VEDIVTSVSTYVENNDMDIIFDTDTEEKIIACDKDMIERVVLNLISNSVKYKQSGKGSIQ
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCHHHHHHHHHHHHHCCCEECCCCCCEEE
VTVQDKEDRVIVSVKDNGIGIPENIQKNVFNRFVQSNRKEYDLTTCSSGIGLALVKSIID
EEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHH
MHDGNIQINSRENKGTEIIFELPSRKVKENEKCKEIYTKNIGKNVKIEFPEIYDSAI
CCCCCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]