BacMap

Definition	Clostridium botulinum A2 str. Kyoto chromosome, complete genome.
Accession	NC_012563
Length	4,155,278

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The map label for this gene is yvsH [H]

Identifier: 226947781

GI number: 226947781

Start: 684775

End: 686124

Strand: Direct

Name: yvsH [H]

Synonym: CLM_0630

Alternate gene names: 226947781

Gene position: 684775-686124 (Clockwise)

Preceding gene: 226947780

Following gene: 226947782

Centisome position: 16.48

GC content: 32.96

Gene sequence:

>1350_bases
ATGGAGGGGAATAATAAATTAAAAAAGGAAATAGGACTTTTTACTGCTACATTTATAGTGGCTGGTAATATAATTGGATC
AGGAATATTTATGCTTCCGGCTACCTTAGCGGAGGTGTCAGGACCAGGAGCTACTATGGCAGCTTGGATTATAACTGGTA
TAGGTTCTATATTTTTAGCATTGTCCTTTGCACGATTAGGATCTAAAATTCCAAAAACGGGAGGTCCTTATCAATATGCT
AAAATAGCTTTTGGAGATTTTGTAGGCTTTACTAATGCATGGCTTTACTGGAGTGCTACATGCATATCCAACGCGGCTAT
AATAACGGCTATAGCAAGCTATTCTTCAAGTTTAGTTCCAGTTTTAAAAACTAATGGATTATACGCTTTTTTATATACCT
CTGCTATATTGTGGGCATTTAATATATTGAACATTATAGGGGTAAAACAAGCCAGTGCCTTTGAAACGGTTATAACTATA
TTTAAATTAGGAGTATTTTTAGTTTTTGTAATAATAGGTTTTGCCAATTTTAATCCACAATACATTACTCCTGCTTTTCC
AAAGGGTAAAGGGTTTAGTACAGTGCCCTTAGCAGCAGCAACTACATTATGGGCATTCTCTGGATTTGAATCCGCTAGTA
TAGCAGCAGGAGAGATAAAAAGTGCTGAAAAAAATGTTAAATTGAGTACTATTTATGGACTTCTAATAGCAGTGCTTGTA
TATTTAGTAATAAGCTTTGTTGCTATGGGCGGATTACCACAGGATATGTTAGCAAAAAGCAATTCTCCTATGAGTGATAT
ATTAGCTCTACATTTAAGTAGTAATGCTGTAAATCTATTTTTATTAGCTATTGTTATAACCATTTTTGGAACTATAGCAG
GATGGATAATGTTAACGGCTAGAATCTCTTATGCAGCAGCTGTAGATGGAATGTTTCCACAAGCTTTTGCTAAGATTCAT
CCTAAATATAGAACTCCTCATGTAGGGATTATAATAAATGGAATATTAACTAATATTGTTCTTTTGATGAACTATACAGG
TTCTATGACTTCTGCTTATAACTTTATGATTTTATTGGCTACGCTAGCATATTTACCTGTATATGCTATAACTAATGCTG
CAGATATATTACTTTTATCTAAAAGAGAAGAAAAATTTAATGTGGGAAATTTTATTATAAATTCTGTTGTTCCATTAATA
GGATTTATTTATGCTATTTGGGCAGTTTATGGAACAGGTGCCGAATCTGCCTTATATGGGCTATTATTAGGTTTAATGGG
CATACCATTTTATATCTATATGAAGATGAAAGACAAAAAACAGATGGAAAAGATAAGAAAACAACAATAA

Upstream 100 bases:

>100_bases
AAATAATAGTATTAATACAATTTAAATAATTATATGAAAATTTTTTATTATAGTATAGTTTATAGATTTTTACTAAAGAT
GAAATGAAAGGAGTATTAAT

Downstream 100 bases:

>100_bases
ATTTTGTAATATAATAATATTTTTAATAAAAAAGTGTCATATACTTTATTGTAATGATATAATAGATTTATTGAAAGCCC
TGTGCAAATGTACAGGGTTT

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MEGNNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLALSFARLGSKIPKTGGPYQYA
KIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVPVLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITI
FKLGVFLVFVIIGFANFNPQYITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTARISYAAAVDGMFPQAFAKIH
PKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLATLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLI
GFIYAIWAVYGTGAESALYGLLLGLMGIPFYIYMKMKDKKQMEKIRKQQ

Sequences:

>Translated_449_residues
MEGNNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLALSFARLGSKIPKTGGPYQYA
KIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVPVLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITI
FKLGVFLVFVIIGFANFNPQYITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTARISYAAAVDGMFPQAFAKIH
PKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLATLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLI
GFIYAIWAVYGTGAESALYGLLLGLMGIPFYIYMKMKDKKQMEKIRKQQ
>Mature_449_residues
MEGNNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLALSFARLGSKIPKTGGPYQYA
KIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVPVLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITI
FKLGVFLVFVIIGFANFNPQYITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTARISYAAAVDGMFPQAFAKIH
PKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLATLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLI
GFIYAIWAVYGTGAESALYGLLLGLMGIPFYIYMKMKDKKQMEKIRKQQ

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=465, Percent_Identity=27.741935483871, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI186910308, Length=459, Percent_Identity=24.8366013071895, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI186910306, Length=459, Percent_Identity=24.8366013071895, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI186910304, Length=459, Percent_Identity=24.8366013071895, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI115648063, Length=445, Percent_Identity=24.4943820224719, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI115648022, Length=445, Percent_Identity=24.4943820224719, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI71979932, Length=369, Percent_Identity=25.7452574525745, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI7657683, Length=329, Percent_Identity=24.0121580547112, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI181337167, Length=331, Percent_Identity=25.9818731117825, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI187423910, Length=368, Percent_Identity=24.7282608695652, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI7657591, Length=368, Percent_Identity=24.7282608695652, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI9790235, Length=381, Percent_Identity=27.0341207349081, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI110347453, Length=364, Percent_Identity=25, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI4507047, Length=427, Percent_Identity=22.0140515222482, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI258614005, Length=370, Percent_Identity=20.5405405405405, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258614003, Length=370, Percent_Identity=20.5405405405405, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI71999149, Length=377, Percent_Identity=24.9336870026525, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI2367353, Length=413, Percent_Identity=33.4140435835351, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1786908, Length=430, Percent_Identity=28.6046511627907, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787890, Length=464, Percent_Identity=24.7844827586207, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790575, Length=447, Percent_Identity=28.6353467561521, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082250, Length=342, Percent_Identity=29.5321637426901, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1786302, Length=412, Percent_Identity=22.8155339805825, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788480, Length=366, Percent_Identity=23.224043715847, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789017, Length=343, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790584, Length=321, Percent_Identity=26.791277258567, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=344, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786789, Length=346, Percent_Identity=21.6763005780347, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=367, Percent_Identity=25.0681198910082, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532491, Length=430, Percent_Identity=22.3255813953488, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982612, Length=359, Percent_Identity=24.2339832869081, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982608, Length=367, Percent_Identity=24.2506811989101, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=345, Percent_Identity=24.0579710144928, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71990446, Length=376, Percent_Identity=23.6702127659574, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71995388, Length=348, Percent_Identity=22.7011494252874, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=348, Percent_Identity=22.7011494252874, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71993915, Length=367, Percent_Identity=22.6158038147139, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=367, Percent_Identity=25.0681198910082, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17533459, Length=462, Percent_Identity=22.7272727272727, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17531343, Length=362, Percent_Identity=20.7182320441989, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193208714, Length=358, Percent_Identity=22.9050279329609, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI32566695, Length=358, Percent_Identity=22.9050279329609, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982623, Length=272, Percent_Identity=25.3676470588235, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321492, Length=359, Percent_Identity=20.6128133704735, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512776, Length=414, Percent_Identity=24.1545893719807, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24666159, Length=414, Percent_Identity=24.1545893719807, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24667468, Length=407, Percent_Identity=24.3243243243243, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24641995, Length=367, Percent_Identity=25.3405994550409, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641993, Length=367, Percent_Identity=25.3405994550409, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221331183, Length=339, Percent_Identity=25.3687315634218, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17647653, Length=339, Percent_Identity=25.3687315634218, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24664379, Length=339, Percent_Identity=25.3687315634218, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24668806, Length=418, Percent_Identity=23.2057416267943, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356285, Length=418, Percent_Identity=23.2057416267943, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668802, Length=418, Percent_Identity=23.2057416267943, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357367, Length=459, Percent_Identity=24.8366013071895, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24651635, Length=364, Percent_Identity=23.9010989010989, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651633, Length=364, Percent_Identity=23.9010989010989, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281366235, Length=375, Percent_Identity=25.0666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007820, Length=375, Percent_Identity=25.0666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45550968, Length=463, Percent_Identity=23.5421166306695, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921172, Length=463, Percent_Identity=23.5421166306695, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007818, Length=376, Percent_Identity=24.7340425531915, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI85725152, Length=376, Percent_Identity=24.7340425531915, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 48380; Mature: 48380

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGNNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LSFARLGSKIPKTGGPYQYAKIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVP
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHCCCCCE
VLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITIFKLGVFLVFVIIGFANFNPQ
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTA
HHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RISYAAAVDGMFPQAFAKIHPKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLA
HHHHHHHHCCCCHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLIGFIYAIWAVYGTGAESALYG
HHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLLGLMGIPFYIYMKMKDKKQMEKIRKQQ
HHHHHHCCCEEEEEEECCHHHHHHHHCCC
>Mature Secondary Structure
MEGNNKLKKEIGLFTATFIVAGNIIGSGIFMLPATLAEVSGPGATMAAWIITGIGSIFLA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LSFARLGSKIPKTGGPYQYAKIAFGDFVGFTNAWLYWSATCISNAAIITAIASYSSSLVP
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHHHCCCCCE
VLKTNGLYAFLYTSAILWAFNILNIIGVKQASAFETVITIFKLGVFLVFVIIGFANFNPQ
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YITPAFPKGKGFSTVPLAAATTLWAFSGFESASIAAGEIKSAEKNVKLSTIYGLLIAVLV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
YLVISFVAMGGLPQDMLAKSNSPMSDILALHLSSNAVNLFLLAIVITIFGTIAGWIMLTA
HHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RISYAAAVDGMFPQAFAKIHPKYRTPHVGIIINGILTNIVLLMNYTGSMTSAYNFMILLA
HHHHHHHHCCCCHHHHHHHCCCCCCCCHHEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TLAYLPVYAITNAADILLLSKREEKFNVGNFIINSVVPLIGFIYAIWAVYGTGAESALYG
HHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LLLGLMGIPFYIYMKMKDKKQMEKIRKQQ
HHHHHHCCCEEEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]