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The map label for this gene is glvC [H]

Identifier: 226947501

GI number: 226947501

Start: 321193

End: 322764

Strand: Direct

Name: glvC [H]

Synonym: CLM_0335

Alternate gene names: 226947501

Gene position: 321193-322764 (Clockwise)

Preceding gene: 226947500

Following gene: 226947502

Centisome position: 7.73

GC content: 32.06

Gene sequence:

>1572_bases
GTGAAAGATTTAATAGTAGACAAAATGCAGATGTTCGCCAAAGCTATAATTGTTCCCGTATTATTTTTACCTATTGTAGG
TGTAATTTTGGCTTTATCTTCCATTTTAAGTAATCCATCTATTGTAGGGGAAAGTGGGCTACTAATGAACATAGGTAAAT
TCATTAGTAGTGGACTTTGGCCTATTATGACAAATTTAAGTATTATTTTCTGTGTGGGAATAGCTATGGGGTTAGCAAAA
GAAAAGAAAGCAGAAGCGGCACTAGTAGCAGTATTTTCATATTTAGTATATTTGGGGGCTAATAATCAATGGCTTACTCT
AACAGGAAAGTTAGTAAAATATAAGGTTCCAGCAGATTTATATGGAACTGGACAGACTCTACAACTAGGATTTCAAGTAA
TAGACATGGGAGTTTTTCTAGGAATGATTCTTGGTGTGGTAGTGGCAATTATTCATAATAAATATTGTAATAAGGAATTT
CCTGGAGCCTTTGGATTATATGGAAATACTAAATTAGTATTTATAGTTTTAACTCCTATTACATTAATATTAGCAGTAGT
GTTTAGTTATATTTGGCCTGTAGTAGCTGCTGGTATTAGCGCTTTAACAGGTTTTATAAATGCAGCTGGAGCTATAGGAG
TATTTTTATACGGATTTTTAAATAGATTCTTAATTCCAACTGGATTACATCATTTAATATGGACACCATTTTCTTACTCT
AACATTGGAGGAGAATTGATTATAAATGGACAAAAATACTATGGAGCTTACAATATATTCTTAGCACAGCTAACTGATCC
GGCTATAAAGGTTTTTGATCCATCAGCAAAATATTTACAGTATGGTATGGTTAAAATGTTTGGATTGGCAGGAGCAGCCT
TAGCTTTTTATAAAACATCTAAACCTGAAAACAAAGTTAAATTAAAGTCTATATTGATACCAGCAGTAGCGACATCAATA
TTAGTTGGAATCACAGAACCTCTAGAATTCACATTTTTGTTTGTAGCACCATTTTTATGGGTAGTGCACTCAGTATTGGA
TGGTATATTCGAAGCAGTAGTTTCATTATTAGGAGTTAGAACTTTTGCGGCGAATGGATTTATAGATTTTATAGCTTATA
ATTTACCAGCAGGAATCGCTAAAACTAAATGGCCTATATTCATAGCTGTTGGATTAGTACAGTTAGCAGTGTATTTCTTT
GTATTTAAATTCTTAATTAAAAAATTTAATCTTAAAACTCCTGGTAGAGAGGATAAGGAAGTAAAGTTAGTAACTAAAAA
AGATTTTAAAGAAAATTTAGCTAAAGCTTCAGGAGAGGTTGCTGCATCCAAAGATTCAGATTTGGCAGGGATAGTAGTTG
AAGCCTTAGGTGGTAAAGAAAATATAGAAAGTGTTGATAATTGCTTTACACGTTTAAGGTTAAAACTTAAAAATATAGAC
GTAGTTGATGAGACAGCTTTAAAAGGAACTGGAGCAGCTGGTGTAATAAAGAAAGGTAATAACGTTCAAGTAATATATGG
ACCAAAAGTAAATGGAATCAGAAATATAGTAGATAAATATCTTGGTAATTAA

Upstream 100 bases:

>100_bases
TAATTTTACAATTTTTTCAACTTAAATTCAAGCCTTTATGTAAAAATTATAAGTTATATTTAAACAAAATAAAACTATGT
TTAAAAAGGAGATGTTATTA

Downstream 100 bases:

>100_bases
TATTAGAAAAATTCAAAACGAATTACTATTTAACTTAACTTGTTTTTTTATAAGGCTTTTGTATTTAAATAGACTAAAAA
GTTTGCTAAATTATAATCAT

Product: PTS system glucose/glucoside family transporter subunit IIBC

Products: NA

Alternate protein names: Maltose permease IIC component; PTS system maltose-specific EIIC component; Maltose-specific phosphotransferase enzyme IIB component; PTS system maltose-specific EIIB component [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MKDLIVDKMQMFAKAIIVPVLFLPIVGVILALSSILSNPSIVGESGLLMNIGKFISSGLWPIMTNLSIIFCVGIAMGLAK
EKKAEAALVAVFSYLVYLGANNQWLTLTGKLVKYKVPADLYGTGQTLQLGFQVIDMGVFLGMILGVVVAIIHNKYCNKEF
PGAFGLYGNTKLVFIVLTPITLILAVVFSYIWPVVAAGISALTGFINAAGAIGVFLYGFLNRFLIPTGLHHLIWTPFSYS
NIGGELIINGQKYYGAYNIFLAQLTDPAIKVFDPSAKYLQYGMVKMFGLAGAALAFYKTSKPENKVKLKSILIPAVATSI
LVGITEPLEFTFLFVAPFLWVVHSVLDGIFEAVVSLLGVRTFAANGFIDFIAYNLPAGIAKTKWPIFIAVGLVQLAVYFF
VFKFLIKKFNLKTPGREDKEVKLVTKKDFKENLAKASGEVAASKDSDLAGIVVEALGGKENIESVDNCFTRLRLKLKNID
VVDETALKGTGAAGVIKKGNNVQVIYGPKVNGIRNIVDKYLGN

Sequences:

>Translated_523_residues
MKDLIVDKMQMFAKAIIVPVLFLPIVGVILALSSILSNPSIVGESGLLMNIGKFISSGLWPIMTNLSIIFCVGIAMGLAK
EKKAEAALVAVFSYLVYLGANNQWLTLTGKLVKYKVPADLYGTGQTLQLGFQVIDMGVFLGMILGVVVAIIHNKYCNKEF
PGAFGLYGNTKLVFIVLTPITLILAVVFSYIWPVVAAGISALTGFINAAGAIGVFLYGFLNRFLIPTGLHHLIWTPFSYS
NIGGELIINGQKYYGAYNIFLAQLTDPAIKVFDPSAKYLQYGMVKMFGLAGAALAFYKTSKPENKVKLKSILIPAVATSI
LVGITEPLEFTFLFVAPFLWVVHSVLDGIFEAVVSLLGVRTFAANGFIDFIAYNLPAGIAKTKWPIFIAVGLVQLAVYFF
VFKFLIKKFNLKTPGREDKEVKLVTKKDFKENLAKASGEVAASKDSDLAGIVVEALGGKENIESVDNCFTRLRLKLKNID
VVDETALKGTGAAGVIKKGNNVQVIYGPKVNGIRNIVDKYLGN
>Mature_523_residues
MKDLIVDKMQMFAKAIIVPVLFLPIVGVILALSSILSNPSIVGESGLLMNIGKFISSGLWPIMTNLSIIFCVGIAMGLAK
EKKAEAALVAVFSYLVYLGANNQWLTLTGKLVKYKVPADLYGTGQTLQLGFQVIDMGVFLGMILGVVVAIIHNKYCNKEF
PGAFGLYGNTKLVFIVLTPITLILAVVFSYIWPVVAAGISALTGFINAAGAIGVFLYGFLNRFLIPTGLHHLIWTPFSYS
NIGGELIINGQKYYGAYNIFLAQLTDPAIKVFDPSAKYLQYGMVKMFGLAGAALAFYKTSKPENKVKLKSILIPAVATSI
LVGITEPLEFTFLFVAPFLWVVHSVLDGIFEAVVSLLGVRTFAANGFIDFIAYNLPAGIAKTKWPIFIAVGLVQLAVYFF
VFKFLIKKFNLKTPGREDKEVKLVTKKDFKENLAKASGEVAASKDSDLAGIVVEALGGKENIESVDNCFTRLRLKLKNID
VVDETALKGTGAAGVIKKGNNVQVIYGPKVNGIRNIVDKYLGN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=36.223506743738, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1787343, Length=522, Percent_Identity=32.9501915708812, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1786894, Length=517, Percent_Identity=33.4622823984526, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010975 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 56730; Mature: 56730

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEHHHHCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure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EEHHHHCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]