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The map label for this gene is menC [H]

Identifier: 226225068

GI number: 226225068

Start: 2571164

End: 2572288

Strand: Reverse

Name: menC [H]

Synonym: Lm4b_02489

Alternate gene names: 226225068

Gene position: 2572288-2571164 (Counterclockwise)

Preceding gene: 226225069

Following gene: 226225067

Centisome position: 88.31

GC content: 38.04

Gene sequence:

>1125_bases
ATGTATTTTCAAGAAGCGAGACTAATTCATGCAGAACTTCCTCTTATTGCACCATTTAAAACAAGTTATGGTGAGCTAAA
CAGTAAAGATTTTTATATTATTGAGTTAGTGAATGAGGAGGGTATACGTGGTTATGGAGAGTTGGAAGCTTTTCCGTTAC
CTGACTATACAGAAGAGACTTTGGGCACTGCTATTTCTATTATTAAACAGCATTTGTTGCCAATCCTTGCGCAGAAAGAA
ATACGAACTCCTGAAGAGGTTAACCAGATGTTTAGCTGGATTCAAGGAAATGAAATGGCGAAAGCGGCTGTGGAGCTTGC
TGTTTGGGATGCTTTTGCAAAAAATGAGAAGCTCTCATTAGCTAAAATGATTGGCGCAAAGAAGGACTCGATTGCGGTTG
GCGTGAGCATTGGTGTGCAGCATAGTGCGGAAGCGTTAGTCCAGTTAGTTAGTCAATATATGGATGAAGGCTACGAAAGA
GTGAAGTTGAAAATCGCACCTAAGAAAGATATTCAATTTGTTAAAGCTGTTCGAGAAAAATTTCCTAATCTAAGCTTGAT
GGCTGATGCGAATTCAGCGTATAATAGAGAAGATTTCTTGTTGTTAAAAGAATTAGATCACTTTAATTTAGAAATGATTG
AGCAACCATTTGGAACTAAGGATTTTGTGGAGCATGCTTGGTTGCAAAAAAAATTAAAAACGCGTATTTGTTTGGACGAG
AATATTAGGTCATTAGATGATTTGAAACAGGCTCATATGTTAGGAAGTTGTCAGGCAGTTAATTTAAAATTAGCGCGCGT
TGGTGGTATGTCTGAGGCTCTTAAGATAGCGAGGTATTGTAGCGATAATAATTTGCTTGTCTGGTGTGGCGGCATGCTTG
AAGCTGGTATAGGTAGGGCTCACAATATTGCACTTGCTGCTAGAGCGGAATTTACTTTCCCAGGAGATATTTCTGCATCA
AATCGTTATTTTAATGAAGATATTGTTTCGCCAGCATTTGTATTAAATCAAGGAAAACTCACTGTGCCAACTGGTCAAGG
GGTTGGAGTTGCTTTAGATTTAGATGTGCTACAAAAATATACTAAATCAACAGAAAGAATTTTGCTAAATAAAGGATGGA
GCTGA

Upstream 100 bases:

>100_bases
GCTCCTTTCTAATCCTTCAAGATGGAGACGTTTTTTTGCAATACCTCAATTTATGCTTGTTATTAGAAAAGAGCGCAAGC
GTTTGAAAAAGGGTGAGTAA

Downstream 100 bases:

>100_bases
AAAAATATTGCTAATATGGAGTATATTGATTAGCTTTGCAGTTGGTATCATTATGGTGCCGATAATTAGGAAGTTTGCTT
TCCGAATTAATGCGGTTGAT

Product: N-acylamino acid racemase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MYFQEARLIHAELPLIAPFKTSYGELNSKDFYIIELVNEEGIRGYGELEAFPLPDYTEETLGTAISIIKQHLLPILAQKE
IRTPEEVNQMFSWIQGNEMAKAAVELAVWDAFAKNEKLSLAKMIGAKKDSIAVGVSIGVQHSAEALVQLVSQYMDEGYER
VKLKIAPKKDIQFVKAVREKFPNLSLMADANSAYNREDFLLLKELDHFNLEMIEQPFGTKDFVEHAWLQKKLKTRICLDE
NIRSLDDLKQAHMLGSCQAVNLKLARVGGMSEALKIARYCSDNNLLVWCGGMLEAGIGRAHNIALAARAEFTFPGDISAS
NRYFNEDIVSPAFVLNQGKLTVPTGQGVGVALDLDVLQKYTKSTERILLNKGWS

Sequences:

>Translated_374_residues
MYFQEARLIHAELPLIAPFKTSYGELNSKDFYIIELVNEEGIRGYGELEAFPLPDYTEETLGTAISIIKQHLLPILAQKE
IRTPEEVNQMFSWIQGNEMAKAAVELAVWDAFAKNEKLSLAKMIGAKKDSIAVGVSIGVQHSAEALVQLVSQYMDEGYER
VKLKIAPKKDIQFVKAVREKFPNLSLMADANSAYNREDFLLLKELDHFNLEMIEQPFGTKDFVEHAWLQKKLKTRICLDE
NIRSLDDLKQAHMLGSCQAVNLKLARVGGMSEALKIARYCSDNNLLVWCGGMLEAGIGRAHNIALAARAEFTFPGDISAS
NRYFNEDIVSPAFVLNQGKLTVPTGQGVGVALDLDVLQKYTKSTERILLNKGWS
>Mature_374_residues
MYFQEARLIHAELPLIAPFKTSYGELNSKDFYIIELVNEEGIRGYGELEAFPLPDYTEETLGTAISIIKQHLLPILAQKE
IRTPEEVNQMFSWIQGNEMAKAAVELAVWDAFAKNEKLSLAKMIGAKKDSIAVGVSIGVQHSAEALVQLVSQYMDEGYER
VKLKIAPKKDIQFVKAVREKFPNLSLMADANSAYNREDFLLLKELDHFNLEMIEQPFGTKDFVEHAWLQKKLKTRICLDE
NIRSLDDLKQAHMLGSCQAVNLKLARVGGMSEALKIARYCSDNNLLVWCGGMLEAGIGRAHNIALAARAEFTFPGDISAS
NRYFNEDIVSPAFVLNQGKLTVPTGQGVGVALDLDVLQKYTKSTERILLNKGWS

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=329, Percent_Identity=26.4437689969605, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 41846; Mature: 41846

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFQEARLIHAELPLIAPFKTSYGELNSKDFYIIELVNEEGIRGYGELEAFPLPDYTEET
CCCCCCEEEEECCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCHHH
LGTAISIIKQHLLPILAQKEIRTPEEVNQMFSWIQGNEMAKAAVELAVWDAFAKNEKLSL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHH
AKMIGAKKDSIAVGVSIGVQHSAEALVQLVSQYMDEGYERVKLKIAPKKDIQFVKAVREK
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHH
FPNLSLMADANSAYNREDFLLLKELDHFNLEMIEQPFGTKDFVEHAWLQKKLKTRICLDE
CCCEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
NIRSLDDLKQAHMLGSCQAVNLKLARVGGMSEALKIARYCSDNNLLVWCGGMLEAGIGRA
HHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHCCCCC
HNIALAARAEFTFPGDISASNRYFNEDIVSPAFVLNQGKLTVPTGQGVGVALDLDVLQKY
CEEEEEEEEEECCCCCCCCCCCCCCHHHCCCCEEEECCEEEECCCCCCEEEEEHHHHHHH
TKSTERILLNKGWS
HHHHHEEEECCCCC
>Mature Secondary Structure
MYFQEARLIHAELPLIAPFKTSYGELNSKDFYIIELVNEEGIRGYGELEAFPLPDYTEET
CCCCCCEEEEECCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCHHH
LGTAISIIKQHLLPILAQKEIRTPEEVNQMFSWIQGNEMAKAAVELAVWDAFAKNEKLSL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHH
AKMIGAKKDSIAVGVSIGVQHSAEALVQLVSQYMDEGYERVKLKIAPKKDIQFVKAVREK
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHH
FPNLSLMADANSAYNREDFLLLKELDHFNLEMIEQPFGTKDFVEHAWLQKKLKTRICLDE
CCCEEEEECCCCCCCCHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
NIRSLDDLKQAHMLGSCQAVNLKLARVGGMSEALKIARYCSDNNLLVWCGGMLEAGIGRA
HHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHCCCCC
HNIALAARAEFTFPGDISASNRYFNEDIVSPAFVLNQGKLTVPTGQGVGVALDLDVLQKY
CEEEEEEEEEECCCCCCCCCCCCCCHHHCCCCEEEECCEEEECCCCCCEEEEEHHHHHHH
TKSTERILLNKGWS
HHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]