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The map label for this gene is ftsX

Identifier: 226225054

GI number: 226225054

Start: 2555919

End: 2556803

Strand: Reverse

Name: ftsX

Synonym: Lm4b_02475b

Alternate gene names: 226225054

Gene position: 2556803-2555919 (Counterclockwise)

Preceding gene: 226225055

Following gene: 226225053

Centisome position: 87.78

GC content: 37.29

Gene sequence:

>885_bases
ATGAAATTTAGGACTGTAGGAAGACATATAAGAGAAAGTTTTAAGAGCCTTTACCGGAATGGTTGGATGACCTTTGCAGC
AGCGAGTGCAGTAACAGTAACACTTATCTTAGTCAGCGTGTTTTTTGCAATATTGATCAACATGAACAAGCTTGCAACGG
ATGTAGAAAACAATGTACAAATTAACGTACATATTTCTCTAAGCGCAGACAAGAAACAGCAGCAAGAACTTGAGAAAAAC
ATTGAGAAGATTGATGGAGTTGATAGTGTCAGCTTTTCTTCTAAGGATGACGAATTGAAGAAATTAGTTGGTGCGTACGG
CAAAAACTTCGAATTGTTTAAACAAGATAATCCACTATACGATGTGTTTGTTGTAGAGGCTAAAGAGCCCACACAAACAA
AGACTATTGCTAAAAAAGTAGAAAAATTACAGTACGTAGATAATGTAGAATATGGTGAGAAAACAGTCGATAAATTGTTT
GATACCTTGAAATGGGGACGATATGCTGGTATTATACTAAGCATTGGGTTGTTACTAACAGCGATGTTCTTAATATCAAA
CACAATCAAGATTGCAATTTTCTCCCGGCGAAGAGAAATAGAAATAATGAAATTAGTAGGAGCGACCAACTGGTTCATAC
GCTGGCCTTTCGTTTTAGAAGGTGCTTGGCTAGGATTAATTGGCTCGATTGTACCAGTTGTGTTAACATTTATAGGCTAT
GTTAATATTTACAACTTGGTGAATCCGAAGTTAGTGACAAGCTCACTATCACTTCTGCCTCCAACACCATTCGCTTATCA
AATTAGTGGCTTGATTATTGCAATCGGCGTACTAATCGGGATTTGGGGAAGCGTAATATCTATCCGCAGATTCTTGAAAG
TCTAA

Upstream 100 bases:

>100_bases
GCAACCCACAACAAAGAAATTGTTAACACATTGAAACACCGGGTAGTCGCTATCGAGAATGGAAGAATTGTTCGAGATGA
GCAGCAAGGAGAATATGGCT

Downstream 100 bases:

>100_bases
CTCAGAAAATTACTTAAATCGAAATAAAAATAATTTAAAAGAAAAAGCTAGGGAGCTTTTTAGGAGGTAAACTTTTTGAA
AAAGAATACGTTTATTGCGA

Product: cell-division protein FtsX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKFRTVGRHIRESFKSLYRNGWMTFAAASAVTVTLILVSVFFAILINMNKLATDVENNVQINVHISLSADKKQQQELEKN
IEKIDGVDSVSFSSKDDELKKLVGAYGKNFELFKQDNPLYDVFVVEAKEPTQTKTIAKKVEKLQYVDNVEYGEKTVDKLF
DTLKWGRYAGIILSIGLLLTAMFLISNTIKIAIFSRRREIEIMKLVGATNWFIRWPFVLEGAWLGLIGSIVPVVLTFIGY
VNIYNLVNPKLVTSSLSLLPPTPFAYQISGLIIAIGVLIGIWGSVISIRRFLKV

Sequences:

>Translated_294_residues
MKFRTVGRHIRESFKSLYRNGWMTFAAASAVTVTLILVSVFFAILINMNKLATDVENNVQINVHISLSADKKQQQELEKN
IEKIDGVDSVSFSSKDDELKKLVGAYGKNFELFKQDNPLYDVFVVEAKEPTQTKTIAKKVEKLQYVDNVEYGEKTVDKLF
DTLKWGRYAGIILSIGLLLTAMFLISNTIKIAIFSRRREIEIMKLVGATNWFIRWPFVLEGAWLGLIGSIVPVVLTFIGY
VNIYNLVNPKLVTSSLSLLPPTPFAYQISGLIIAIGVLIGIWGSVISIRRFLKV
>Mature_294_residues
MKFRTVGRHIRESFKSLYRNGWMTFAAASAVTVTLILVSVFFAILINMNKLATDVENNVQINVHISLSADKKQQQELEKN
IEKIDGVDSVSFSSKDDELKKLVGAYGKNFELFKQDNPLYDVFVVEAKEPTQTKTIAKKVEKLQYVDNVEYGEKTVDKLF
DTLKWGRYAGIILSIGLLLTAMFLISNTIKIAIFSRRREIEIMKLVGATNWFIRWPFVLEGAWLGLIGSIVPVVLTFIGY
VNIYNLVNPKLVTSSLSLLPPTPFAYQISGLIIAIGVLIGIWGSVISIRRFLKV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=225, Percent_Identity=28, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 33145; Mature: 33145

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRTVGRHIRESFKSLYRNGWMTFAAASAVTVTLILVSVFFAILINMNKLATDVENNVQ
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
INVHISLSADKKQQQELEKNIEKIDGVDSVSFSSKDDELKKLVGAYGKNFELFKQDNPLY
EEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEE
DVFVVEAKEPTQTKTIAKKVEKLQYVDNVEYGEKTVDKLFDTLKWGRYAGIILSIGLLLT
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMFLISNTIKIAIFSRRREIEIMKLVGATNWFIRWPFVLEGAWLGLIGSIVPVVLTFIGY
HHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VNIYNLVNPKLVTSSLSLLPPTPFAYQISGLIIAIGVLIGIWGSVISIRRFLKV
HHHHHHCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFRTVGRHIRESFKSLYRNGWMTFAAASAVTVTLILVSVFFAILINMNKLATDVENNVQ
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
INVHISLSADKKQQQELEKNIEKIDGVDSVSFSSKDDELKKLVGAYGKNFELFKQDNPLY
EEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCEE
DVFVVEAKEPTQTKTIAKKVEKLQYVDNVEYGEKTVDKLFDTLKWGRYAGIILSIGLLLT
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMFLISNTIKIAIFSRRREIEIMKLVGATNWFIRWPFVLEGAWLGLIGSIVPVVLTFIGY
HHHHHHCCCEEEEECCCCHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VNIYNLVNPKLVTSSLSLLPPTPFAYQISGLIIAIGVLIGIWGSVISIRRFLKV
HHHHHHCCCHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]