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The map label for this gene is csd [H]

Identifier: 226224961

GI number: 226224961

Start: 2455043

End: 2456269

Strand: Reverse

Name: csd [H]

Synonym: Lm4b_02382

Alternate gene names: 226224961

Gene position: 2456269-2455043 (Counterclockwise)

Preceding gene: 226224962

Following gene: 226224960

Centisome position: 84.33

GC content: 41.89

Gene sequence:

>1227_bases
ATGATTGATATCCAAAAAATTCGGGCGGATTTTCCAATTTTAGCTCAAGAAATAAATGAAAAACCGCTAGCTTATTTAGA
TAATGCTGCCACTTCACAAAAGCCGAAACAAGTTATTGAAGCTTTAACACATTACTATGAGTTTGATAATGCGAACGTTC
ACCGCGGTGTGCATACACTTGCAGCAAGAGCGACGGATGCTTATGAATCAGCTCGAGGTAAAGTAGCCAAGTTTATTCAT
GCGCGTGAAGTAGCAGAAATTATTTTCACAAGAGGTACTACTTCAGCGATTAATTTAGTTGTAGATAGTTACGCGGAAGC
AAATATTGAAGCTGGCGATGAGATTGTTATTTCTTATCTAGAGCATCATTCCAATTTGATTCCGTGGCAACAACTAGCTA
AACGCAAGGGCGCGGTTTTGAAATATATCGAACTAGAAGAAGATGGCACGATTTCTGTGGAACAAGCGAAAAAAACGATT
GGTGAAAAAACGAAAATCGTTGCATTAGCTCATGTTTCTAATGTACTCGGGACTATCACGCCAATGAAAGAAATCGCAGC
AATTGCTCATCAATTTGGAGCAGTCATTCTCGTTGACGGTGCGCAAGCGGTGCCTCACATGGAAGTTGATGTAGTTGATT
TAGATGCTGACTTTTATGCTTTTTCAGGGCACAAAATGATGGCTCCTACTGGCATTGGCGCCTTGTATGGCAAACGTGAA
TTGCTTGATGCGATGGAACCTACCGAATTTGGCGGAGAAATGATTGATTTTGTTGAATTATACGATTCGACTTGGAAAGA
ACTGCCGTGGAAATTTGAAGCCGGAACACCGATTATTGGCGGAGCGATTGCGCTAGGTGCGGCGATTGATTACTTGGCAG
AAGTCGGACTCGCAAATATTCACGCACATGAACAAGCATTAGCCAGCTACGCGATAGAAGAAATGAGCAAAATCGAAGGC
ATTACCATTTATGGACCAAAAGACGCGAGTAAACGATGTGGCTTAGTGACTTTCAATTTAGAAGGCGCACACCCACACGA
TATTGCGACTATTTTGGACGAAGACGGAATTGCGATTCGAGCTGGTCACCACTGTGCGCAACCGTTGATGAAGTGGCTTG
ACGTTTCTTCCACAGCTCGCGCAAGCTTTTATATTTATAATACAAAAGAAGAAATTGATGCGCTTATAGATGGCCTCAAG
TTAACAAAGGAGTATTTTGGATTATGA

Upstream 100 bases:

>100_bases
ATTAGTTATTCATGGCTTCTTAGATCCTGTTGTTCGTCAGTTACCAATCGAAAGTGTGAAAACGATGCTTCGTGAAGTAA
TCGAAGGGAAAGTGCGCTAA

Downstream 100 bases:

>100_bases
CAAGCCGGAAATTAGATCAGCTTTATAGACAAGTCATTATGGATCACTATAAAAATCCGCGCAATAATGGAGAGCTCCCA
GATAGCGATGTAACAATCGA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MIDIQKIRADFPILAQEINEKPLAYLDNAATSQKPKQVIEALTHYYEFDNANVHRGVHTLAARATDAYESARGKVAKFIH
AREVAEIIFTRGTTSAINLVVDSYAEANIEAGDEIVISYLEHHSNLIPWQQLAKRKGAVLKYIELEEDGTISVEQAKKTI
GEKTKIVALAHVSNVLGTITPMKEIAAIAHQFGAVILVDGAQAVPHMEVDVVDLDADFYAFSGHKMMAPTGIGALYGKRE
LLDAMEPTEFGGEMIDFVELYDSTWKELPWKFEAGTPIIGGAIALGAAIDYLAEVGLANIHAHEQALASYAIEEMSKIEG
ITIYGPKDASKRCGLVTFNLEGAHPHDIATILDEDGIAIRAGHHCAQPLMKWLDVSSTARASFYIYNTKEEIDALIDGLK
LTKEYFGL

Sequences:

>Translated_408_residues
MIDIQKIRADFPILAQEINEKPLAYLDNAATSQKPKQVIEALTHYYEFDNANVHRGVHTLAARATDAYESARGKVAKFIH
AREVAEIIFTRGTTSAINLVVDSYAEANIEAGDEIVISYLEHHSNLIPWQQLAKRKGAVLKYIELEEDGTISVEQAKKTI
GEKTKIVALAHVSNVLGTITPMKEIAAIAHQFGAVILVDGAQAVPHMEVDVVDLDADFYAFSGHKMMAPTGIGALYGKRE
LLDAMEPTEFGGEMIDFVELYDSTWKELPWKFEAGTPIIGGAIALGAAIDYLAEVGLANIHAHEQALASYAIEEMSKIEG
ITIYGPKDASKRCGLVTFNLEGAHPHDIATILDEDGIAIRAGHHCAQPLMKWLDVSSTARASFYIYNTKEEIDALIDGLK
LTKEYFGL
>Mature_408_residues
MIDIQKIRADFPILAQEINEKPLAYLDNAATSQKPKQVIEALTHYYEFDNANVHRGVHTLAARATDAYESARGKVAKFIH
AREVAEIIFTRGTTSAINLVVDSYAEANIEAGDEIVISYLEHHSNLIPWQQLAKRKGAVLKYIELEEDGTISVEQAKKTI
GEKTKIVALAHVSNVLGTITPMKEIAAIAHQFGAVILVDGAQAVPHMEVDVVDLDADFYAFSGHKMMAPTGIGALYGKRE
LLDAMEPTEFGGEMIDFVELYDSTWKELPWKFEAGTPIIGGAIALGAAIDYLAEVGLANIHAHEQALASYAIEEMSKIEG
ITIYGPKDASKRCGLVTFNLEGAHPHDIATILDEDGIAIRAGHHCAQPLMKWLDVSSTARASFYIYNTKEEIDALIDGLK
LTKEYFGL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=232, Percent_Identity=29.7413793103448, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI156713448, Length=260, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787970, Length=408, Percent_Identity=50, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1789175, Length=394, Percent_Identity=42.3857868020305, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI48994898, Length=230, Percent_Identity=30, Blast_Score=109, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193211090, Length=375, Percent_Identity=27.2, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25143064, Length=228, Percent_Identity=29.3859649122807, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319831, Length=232, Percent_Identity=30.6034482758621, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI20129463, Length=242, Percent_Identity=30.9917355371901, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44721; Mature: 44721

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIQKIRADFPILAQEINEKPLAYLDNAATSQKPKQVIEALTHYYEFDNANVHRGVHTL
CCCHHHHHCCCCHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
AARATDAYESARGKVAKFIHAREVAEIIFTRGTTSAINLVVDSYAEANIEAGDEIVISYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
EHHSNLIPWQQLAKRKGAVLKYIELEEDGTISVEQAKKTIGEKTKIVALAHVSNVLGTIT
HHCCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEEEHHHHHHHHHHCC
PMKEIAAIAHQFGAVILVDGAQAVPHMEVDVVDLDADFYAFSGHKMMAPTGIGALYGKRE
CHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCEEEECCCEEECCCCCHHHHHHHH
LLDAMEPTEFGGEMIDFVELYDSTWKELPWKFEAGTPIIGGAIALGAAIDYLAEVGLANI
HHHHCCCCHHCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHH
HAHEQALASYAIEEMSKIEGITIYGPKDASKRCGLVTFNLEGAHPHDIATILDEDGIAIR
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCEEE
AGHHCAQPLMKWLDVSSTARASFYIYNTKEEIDALIDGLKLTKEYFGL
CCCHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDIQKIRADFPILAQEINEKPLAYLDNAATSQKPKQVIEALTHYYEFDNANVHRGVHTL
CCCHHHHHCCCCHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
AARATDAYESARGKVAKFIHAREVAEIIFTRGTTSAINLVVDSYAEANIEAGDEIVISYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
EHHSNLIPWQQLAKRKGAVLKYIELEEDGTISVEQAKKTIGEKTKIVALAHVSNVLGTIT
HHCCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEEEHHHHHHHHHHCC
PMKEIAAIAHQFGAVILVDGAQAVPHMEVDVVDLDADFYAFSGHKMMAPTGIGALYGKRE
CHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCEEEECCCEEECCCCCHHHHHHHH
LLDAMEPTEFGGEMIDFVELYDSTWKELPWKFEAGTPIIGGAIALGAAIDYLAEVGLANI
HHHHCCCCHHCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHH
HAHEQALASYAIEEMSKIEGITIYGPKDASKRCGLVTFNLEGAHPHDIATILDEDGIAIR
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCEEE
AGHHCAQPLMKWLDVSSTARASFYIYNTKEEIDALIDGLKLTKEYFGL
CCCHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]