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The map label for this gene is sufB [H]

Identifier: 226224959

GI number: 226224959

Start: 2453186

End: 2454580

Strand: Reverse

Name: sufB [H]

Synonym: Lm4b_02380

Alternate gene names: 226224959

Gene position: 2454580-2453186 (Counterclockwise)

Preceding gene: 226224960

Following gene: 226224958

Centisome position: 84.27

GC content: 41.65

Gene sequence:

>1395_bases
ATGACTGAAATTCCAGAAATTGGCGAATACCAATATGGATTCCATGACAAAGATACCTCTGTGTTCCGTACAGAACGCGG
ATTAACAGAAAAAGTAGTAAGAGAAATTTCGAATATTAAAGAAGAACCAGAATGGATGCTTGAATTCCGTTTGAAGTCTT
TGGAGCAATTTTATAAAATGCCAATGCCGACTTGGGGTGGCGACCTGTCAGAACTTAAGTTTGAAGACATCACTTACTAC
GTGAAACCGTCTGAACAAACAGTGCGCTCTTGGGATGAAGTTCCTGAAGAAATTAAACGTACTTTTGATAAATTAGGTAT
TCCTGAAGCCGAACAAAAATATTTGGCTGGGGCATCTGCACAGTATGAATCCGAAGTAGTTTATCACAATATGAAGCAAG
ACCTAGAAGATTTAGGGATTGTCTTCAAAGATACAGATTCCGCGTTAAAAGAAAACGAAGATATTTTCAAAGAATATTTC
GCAAAAGTAATTCCACCAAGCGACAACAAATTCGCTGCGCTAAACTCGGCTGTTTGGTCAGGTGGCTCATTCATCTACGT
ACCACCAGGTATCAAAGTAGATACGCCACTTCAAGCCTATTTCCGCATTAACTCGGAAAACATGGGTCAATTTGAGCGGA
CACTAATTATTGTGGACGAAAATGCCAGCGTAAACTACGTGGAAGGCTGTACTGCTCCCGTTTATACTACGAATTCCCTT
CACTCTGCTGTCGTGGAAATCATTGTAAAACCAGGCGCTTACTGTCGTTACACAACCATCCAAAACTGGGCAAATAACGT
TTACAACCTAGTAACGAAACGTACTTTCTGTGAAGAAAATGCGACAATGGAATGGATTGATGGCAACATTGGTTCGAAAT
TAACAATGAAATACCCAGCTGTACATTTACGAGGCGAAGGAGCACGTGGAACGACCCTTTCTATCGCGATTGCTGGTAAA
GGCCAACGTCAAGACGCTGGAGCAAAAATGATGCACTATGCGCCGAATACGTCCTCTACGATTGTGTCGAAGTCGATCTC
GAAACAAGGCGGAAACGTAACGTATCGCGGAATTGTTCATTTTGGTCGTAATGCAGACGGTGCACGTTCGAATATCGAAT
GTGATACGCTGATTATGGATAACCTGTCCACATCGGACACAATCCCGTACAACGAAATCCTAAACAGCAACATCTCATTA
GAACACGAAGCCAAAGTTTCCAAAGTATCCGAGGAACAACTTTTCTATCTAATGAGCCGTGGTTTAAGCGAAGAAGAAGC
GACAGAAATGATCGTTATGGGCTTCATTGAACCATTTACGAAAGAATTGCCAATGGAATATGCCGTTGAGATGAACCGTT
TGATTAAGTTTGAAATGGAAGGCTCGATTGGTTAA

Upstream 100 bases:

>100_bases
CCAGCAAGAATCAAATGTGCAACCCTTTCTTGGAAAGCAATGGAGAGAGCGATTTTTGAAAAAGAAGGAACAAAATAAGT
AGCGAAAAGGAGGATACGAC

Downstream 100 bases:

>100_bases
ATAAAGCAAAAGACGAACTTTTTAGTTCGTCTTTTTTTGATGAAATCCAAAAATAGCAGGGAATAAATCTGGCTTGTATT
TTTATAAATGAAGTGATATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTEIPEIGEYQYGFHDKDTSVFRTERGLTEKVVREISNIKEEPEWMLEFRLKSLEQFYKMPMPTWGGDLSELKFEDITYY
VKPSEQTVRSWDEVPEEIKRTFDKLGIPEAEQKYLAGASAQYESEVVYHNMKQDLEDLGIVFKDTDSALKENEDIFKEYF
AKVIPPSDNKFAALNSAVWSGGSFIYVPPGIKVDTPLQAYFRINSENMGQFERTLIIVDENASVNYVEGCTAPVYTTNSL
HSAVVEIIVKPGAYCRYTTIQNWANNVYNLVTKRTFCEENATMEWIDGNIGSKLTMKYPAVHLRGEGARGTTLSIAIAGK
GQRQDAGAKMMHYAPNTSSTIVSKSISKQGGNVTYRGIVHFGRNADGARSNIECDTLIMDNLSTSDTIPYNEILNSNISL
EHEAKVSKVSEEQLFYLMSRGLSEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG

Sequences:

>Translated_464_residues
MTEIPEIGEYQYGFHDKDTSVFRTERGLTEKVVREISNIKEEPEWMLEFRLKSLEQFYKMPMPTWGGDLSELKFEDITYY
VKPSEQTVRSWDEVPEEIKRTFDKLGIPEAEQKYLAGASAQYESEVVYHNMKQDLEDLGIVFKDTDSALKENEDIFKEYF
AKVIPPSDNKFAALNSAVWSGGSFIYVPPGIKVDTPLQAYFRINSENMGQFERTLIIVDENASVNYVEGCTAPVYTTNSL
HSAVVEIIVKPGAYCRYTTIQNWANNVYNLVTKRTFCEENATMEWIDGNIGSKLTMKYPAVHLRGEGARGTTLSIAIAGK
GQRQDAGAKMMHYAPNTSSTIVSKSISKQGGNVTYRGIVHFGRNADGARSNIECDTLIMDNLSTSDTIPYNEILNSNISL
EHEAKVSKVSEEQLFYLMSRGLSEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
>Mature_463_residues
TEIPEIGEYQYGFHDKDTSVFRTERGLTEKVVREISNIKEEPEWMLEFRLKSLEQFYKMPMPTWGGDLSELKFEDITYYV
KPSEQTVRSWDEVPEEIKRTFDKLGIPEAEQKYLAGASAQYESEVVYHNMKQDLEDLGIVFKDTDSALKENEDIFKEYFA
KVIPPSDNKFAALNSAVWSGGSFIYVPPGIKVDTPLQAYFRINSENMGQFERTLIIVDENASVNYVEGCTAPVYTTNSLH
SAVVEIIVKPGAYCRYTTIQNWANNVYNLVTKRTFCEENATMEWIDGNIGSKLTMKYPAVHLRGEGARGTTLSIAIAGKG
QRQDAGAKMMHYAPNTSSTIVSKSISKQGGNVTYRGIVHFGRNADGARSNIECDTLIMDNLSTSDTIPYNEILNSNISLE
HEAKVSKVSEEQLFYLMSRGLSEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=461, Percent_Identity=39.9132321041215, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1787971, Length=154, Percent_Identity=25.974025974026, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 52517; Mature: 52386

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIPEIGEYQYGFHDKDTSVFRTERGLTEKVVREISNIKEEPEWMLEFRLKSLEQFYKM
CCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PMPTWGGDLSELKFEDITYYVKPSEQTVRSWDEVPEEIKRTFDKLGIPEAEQKYLAGASA
CCCCCCCCHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
QYESEVVYHNMKQDLEDLGIVFKDTDSALKENEDIFKEYFAKVIPPSDNKFAALNSAVWS
CHHHHHHHHHHHHHHHHCCEEEECCCHHHHCCHHHHHHHHHHHCCCCCCCEEEEHHHHCC
GGSFIYVPPGIKVDTPLQAYFRINSENMGQFERTLIIVDENASVNYVEGCTAPVYTTNSL
CCCEEEECCCCEECCCCEEEEEECCCCCCCEEEEEEEEECCCCEEEECCCCCCEEECCHH
HSAVVEIIVKPGAYCRYTTIQNWANNVYNLVTKRTFCEENATMEWIDGNIGSKLTMKYPA
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCE
VHLRGEGARGTTLSIAIAGKGQRQDAGAKMMHYAPNTSSTIVSKSISKQGGNVTYRGIVH
EEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEE
FGRNADGARSNIECDTLIMDNLSTSDTIPYNEILNSNISLEHEAKVSKVSEEQLFYLMSR
ECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GLSEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCC
>Mature Secondary Structure 
TEIPEIGEYQYGFHDKDTSVFRTERGLTEKVVREISNIKEEPEWMLEFRLKSLEQFYKM
CCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PMPTWGGDLSELKFEDITYYVKPSEQTVRSWDEVPEEIKRTFDKLGIPEAEQKYLAGASA
CCCCCCCCHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
QYESEVVYHNMKQDLEDLGIVFKDTDSALKENEDIFKEYFAKVIPPSDNKFAALNSAVWS
CHHHHHHHHHHHHHHHHCCEEEECCCHHHHCCHHHHHHHHHHHCCCCCCCEEEEHHHHCC
GGSFIYVPPGIKVDTPLQAYFRINSENMGQFERTLIIVDENASVNYVEGCTAPVYTTNSL
CCCEEEECCCCEECCCCEEEEEECCCCCCCEEEEEEEEECCCCEEEECCCCCCEEECCHH
HSAVVEIIVKPGAYCRYTTIQNWANNVYNLVTKRTFCEENATMEWIDGNIGSKLTMKYPA
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCE
VHLRGEGARGTTLSIAIAGKGQRQDAGAKMMHYAPNTSSTIVSKSISKQGGNVTYRGIVH
EEEECCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEE
FGRNADGARSNIECDTLIMDNLSTSDTIPYNEILNSNISLEHEAKVSKVSEEQLFYLMSR
ECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
GLSEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]