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The map label for this gene is comK

Identifier: 226224878

GI number: 226224878

Start: 2366383

End: 2366991

Strand: Direct

Name: comK

Synonym: Lm4b_02297

Alternate gene names: 226224878

Gene position: 2366383-2366991 (Clockwise)

Preceding gene: 226224871

Following gene: 226224883

Centisome position: 81.24

GC content: 34.32

Gene sequence:

>609_bases
ATGAAAAAAGAACAAATCAGTACTCAGTTTTATGAAGTAAACCCGCACACAATGATTATTTTTCCAAAAAAATCTGGAAG
TATAGTCTATTCAGAAATTTATGAAGTTGATTCCCATTGTACTTCTAAATTTACCCCGTTTGAACTAATTAAAACCAGCT
GTAACTTTTTCGGATCAAGCTATGAGGGACGCAAAGAGGGAACTAAACACTTAATTGGTGTTACCCATAAGCCACCCATT
ATCATTGACCCAGTCACTTCTACTTATGTATTTCCAACTGTAGCACCTAGTTCAACAGAATGTATTTGGATTTTCCCACA
ACATATTAAAGATTATCATGCAATTGGATTTAACCACACTTTAATAACATTTTCTAATATGGAAACCTTTGAGATTGATA
TGTCTTTAGCATCTTTTAATAATCAGATTGCTAGAACCTCCATGTTACATATGAAATTTTCTCAAAAAATGCGTATAATG
GAGAGTAATTTTCCTTCAATGAATAGGTTTTTCCCACCAACCACTCTTGCTGCTGAACCTAGACGTTATTACAGCACCAT
GCTTCCAAATAACGAAGATCCTAATGAGCCTCAAGATCCTGAGCAGTAA

Upstream 100 bases:

>100_bases
TAACTTTGATGCTTAGTCGTTACTTAGAAGTTTTGCTTATTAGGCAATAACTCTAGGTTTCTTCTTAGACATAAATACAA
ACATAGAGGAGTTGAATGAA

Downstream 100 bases:

>100_bases
CTTTAAAACCAAATAAAAGCCAGTTACATAATAGTAGCTGGCTTCTCCTTAAAATTATTTTTTATTTTCAATCGCATCTG
CAATTCGTTTTAACATTAAT

Product: competence transcription factor

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKKEQISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHCTSKFTPFELIKTSCNFFGSSYEGRKEGTKHLIGVTHKPPI
IIDPVTSTYVFPTVAPSSTECIWIFPQHIKDYHAIGFNHTLITFSNMETFEIDMSLASFNNQIARTSMLHMKFSQKMRIM
ESNFPSMNRFFPPTTLAAEPRRYYSTMLPNNEDPNEPQDPEQ

Sequences:

>Translated_202_residues
MKKEQISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHCTSKFTPFELIKTSCNFFGSSYEGRKEGTKHLIGVTHKPPI
IIDPVTSTYVFPTVAPSSTECIWIFPQHIKDYHAIGFNHTLITFSNMETFEIDMSLASFNNQIARTSMLHMKFSQKMRIM
ESNFPSMNRFFPPTTLAAEPRRYYSTMLPNNEDPNEPQDPEQ
>Mature_202_residues
MKKEQISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHCTSKFTPFELIKTSCNFFGSSYEGRKEGTKHLIGVTHKPPI
IIDPVTSTYVFPTVAPSSTECIWIFPQHIKDYHAIGFNHTLITFSNMETFEIDMSLASFNNQIARTSMLHMKFSQKMRIM
ESNFPSMNRFFPPTTLAAEPRRYYSTMLPNNEDPNEPQDPEQ

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 23342; Mature: 23342

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEQISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHCTSKFTPFELIKTSCNFFGSS
CCCHHCCCEEEEECCCEEEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
YEGRKEGTKHLIGVTHKPPIIIDPVTSTYVFPTVAPSSTECIWIFPQHIKDYHAIGFNHT
CCCCCCCCCEEEEECCCCCEEECCCCCEEEEEEECCCCCCEEEEEHHHCCCHHHCCCCEE
LITFSNMETFEIDMSLASFNNQIARTSMLHMKFSQKMRIMESNFPSMNRFFPPTTLAAEP
EEEECCCEEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
RRYYSTMLPNNEDPNEPQDPEQ
HHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKEQISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHCTSKFTPFELIKTSCNFFGSS
CCCHHCCCEEEEECCCEEEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
YEGRKEGTKHLIGVTHKPPIIIDPVTSTYVFPTVAPSSTECIWIFPQHIKDYHAIGFNHT
CCCCCCCCCEEEEECCCCCEEECCCCCEEEEEEECCCCCCEEEEEHHHCCCHHHCCCCEE
LITFSNMETFEIDMSLASFNNQIARTSMLHMKFSQKMRIMESNFPSMNRFFPPTTLAAEP
EEEECCCEEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
RRYYSTMLPNNEDPNEPQDPEQ
HHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]