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The map label for this gene is aspC [H]

Identifier: 226224860

GI number: 226224860

Start: 2347805

End: 2348956

Strand: Direct

Name: aspC [H]

Synonym: Lm4b_02279

Alternate gene names: 226224860

Gene position: 2347805-2348956 (Clockwise)

Preceding gene: 226224859

Following gene: 226224862

Centisome position: 80.61

GC content: 37.24

Gene sequence:

>1152_bases
ATGATGAATAACTCAAAAATTGCTAAAAAACATCAACAAATGCCTGTGAACATTCTTGCTGATATTGGCACACTTGCCAA
AACAATGCCTGATATTCTCGATTTATCCATTGGTGATCCTGATTTAATTACGGATGAATCGATTATTAATGCCGCTTTTG
AAGACGTACGGGCAGGCCATACAAAATACACAGAATCTGGTGGAGATGTAGAACTCATAGATGCTATTCGTGGTTATTTT
AGCCGTAATTATGATTTGTCTTTTGAACGCAGCCAAATCCGCGCTACAGTTGGCGCGCTTCATGGTATGTACCTAACCTT
GCAAACCATTCTCGACGACGGCGATGAAGTCATTATTCACGAACCCTACTTCTCCCCGTATAAAGATCAAGTGTTAAATT
CCGGTGGTACTCCTATCATTATTCCAACCTATGAGAAAGACGATTTTGCGATTAATGTCGATATTTTAGAAGCTGCCATT
ACTGATAAAACAAAAGCTTTAATTTTAAATTCACCTAATAATCCCACCGGTGCTGTTTTTTCACCGGAAACCTTTGAAAA
AATTGCTAATCTAGCGAAAAAATATGACTTTTTTATTTTGTCGGATGAAGTATATGATGGTTTTAGTTTTTATGAAGACT
TCGTACCAATGGCCAAATTCGCGCCAGATCACACGATTACATTTGGTAGTATGTCTAAAAACTTCGCAATGACCGGTTGG
CGCTTAGGATATATGATTGCTCCTACTTATTTAAACGAAGCTGCAAAGATTATTAATGAAGGAATTACTTATTCAGCTCC
TACACCGTCCCAAAGAGCTGCTATTTACGCATTAAATCATTCTGAGACACTAATTCCTTTAGTAACAGAAACTTTCCAAA
AACGCCTAGAATACATCGCAAAACGGGTGGAAGAAATCCCATATCTTTCTTTACATCCACTTAAAGGTTCGATTTACGCC
TTTATTAATATTTCTAAAACAAATATGGATTCTGTTTCATTTACAGAATATGTCTTAAAAGAAACACAAGTCCTCGTCAT
TCCTGGGCTAGCTTTTGGTGAATCTGGTGATAATTATGTTCGCCTAGCTGCAACCCAAGACATTAGCGTGCTAGAAGAAG
CATTTAACCGTCTAGCCAAATTAACCTTTTAA

Upstream 100 bases:

>100_bases
AGACTTTTTAGGAAAAGTTTTAGCATAACCAAAGATTACGTCTCGCCTATTTTAGGTGAGGCGTTTATCTGCACTTATAG
AAAAAAGGAGCTAATTATAC

Downstream 100 bases:

>100_bases
CAAAAAGAGCAAACTCGCTTCATAGGCAAGTTTGCTCTTTTTTCTATTTTAAATTGATTTCTGCAAAAGAAGAAACAACC
GTCGCCTCTTTTGGAAAAGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MMNNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGHTKYTESGGDVELIDAIRGYF
SRNYDLSFERSQIRATVGALHGMYLTLQTILDDGDEVIIHEPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVDILEAAI
TDKTKALILNSPNNPTGAVFSPETFEKIANLAKKYDFFILSDEVYDGFSFYEDFVPMAKFAPDHTITFGSMSKNFAMTGW
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPLVTETFQKRLEYIAKRVEEIPYLSLHPLKGSIYA
FINISKTNMDSVSFTEYVLKETQVLVIPGLAFGESGDNYVRLAATQDISVLEEAFNRLAKLTF

Sequences:

>Translated_383_residues
MMNNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGHTKYTESGGDVELIDAIRGYF
SRNYDLSFERSQIRATVGALHGMYLTLQTILDDGDEVIIHEPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVDILEAAI
TDKTKALILNSPNNPTGAVFSPETFEKIANLAKKYDFFILSDEVYDGFSFYEDFVPMAKFAPDHTITFGSMSKNFAMTGW
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPLVTETFQKRLEYIAKRVEEIPYLSLHPLKGSIYA
FINISKTNMDSVSFTEYVLKETQVLVIPGLAFGESGDNYVRLAATQDISVLEEAFNRLAKLTF
>Mature_383_residues
MMNNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGHTKYTESGGDVELIDAIRGYF
SRNYDLSFERSQIRATVGALHGMYLTLQTILDDGDEVIIHEPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVDILEAAI
TDKTKALILNSPNNPTGAVFSPETFEKIANLAKKYDFFILSDEVYDGFSFYEDFVPMAKFAPDHTITFGSMSKNFAMTGW
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPLVTETFQKRLEYIAKRVEEIPYLSLHPLKGSIYA
FINISKTNMDSVSFTEYVLKETQVLVIPGLAFGESGDNYVRLAATQDISVLEEAFNRLAKLTF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=404, Percent_Identity=26.4851485148515, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI56713254, Length=404, Percent_Identity=26.4851485148515, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=24.2966751918159, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=24.2966751918159, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169881281, Length=302, Percent_Identity=24.1721854304636, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=25, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI19263340, Length=401, Percent_Identity=22.6932668329177, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI215599424, Length=396, Percent_Identity=22.7272727272727, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI149944424, Length=207, Percent_Identity=27.0531400966184, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=30.4812834224599, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=24.9357326478149, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788627, Length=292, Percent_Identity=27.3972602739726, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787909, Length=394, Percent_Identity=23.3502538071066, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=418, Percent_Identity=28.4688995215311, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71994476, Length=418, Percent_Identity=28.4688995215311, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17567369, Length=353, Percent_Identity=30.5949008498584, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17567663, Length=405, Percent_Identity=25.9259259259259, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=363, Percent_Identity=28.9256198347107, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573069, Length=391, Percent_Identity=29.923273657289, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24646114, Length=391, Percent_Identity=29.923273657289, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28573067, Length=391, Percent_Identity=29.923273657289, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28573065, Length=391, Percent_Identity=29.923273657289, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI21356535, Length=396, Percent_Identity=24.7474747474747, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI18859735, Length=394, Percent_Identity=22.5888324873096, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42721; Mature: 42721

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGH
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
TKYTESGGDVELIDAIRGYFSRNYDLSFERSQIRATVGALHGMYLTLQTILDDGDEVIIH
CEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVDILEAAITDKTKALILNSPNNPTGAVF
CCCCCCHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCEE
SPETFEKIANLAKKYDFFILSDEVYDGFSFYEDFVPMAKFAPDHTITFGSMSKNFAMTGW
CHHHHHHHHHHHHHCCEEEEEHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCE
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPLVTETFQKRLEYIA
EEEEEECHHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
KRVEEIPYLSLHPLKGSIYAFINISKTNMDSVSFTEYVLKETQVLVIPGLAFGESGDNYV
HHHHHCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEECCEEECCCCCCEE
RLAATQDISVLEEAFNRLAKLTF
EEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMNNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGH
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
TKYTESGGDVELIDAIRGYFSRNYDLSFERSQIRATVGALHGMYLTLQTILDDGDEVIIH
CEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVDILEAAITDKTKALILNSPNNPTGAVF
CCCCCCHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCEE
SPETFEKIANLAKKYDFFILSDEVYDGFSFYEDFVPMAKFAPDHTITFGSMSKNFAMTGW
CHHHHHHHHHHHHHCCEEEEEHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCE
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPLVTETFQKRLEYIA
EEEEEECHHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
KRVEEIPYLSLHPLKGSIYAFINISKTNMDSVSFTEYVLKETQVLVIPGLAFGESGDNYV
HHHHHCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEECCEEECCCCCCEE
RLAATQDISVLEEAFNRLAKLTF
EEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]