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The map label for this gene is pdxS [H]

Identifier: 226224706

GI number: 226224706

Start: 2180963

End: 2181850

Strand: Direct

Name: pdxS [H]

Synonym: Lm4b_02122

Alternate gene names: 226224706

Gene position: 2180963-2181850 (Clockwise)

Preceding gene: 226224698

Following gene: 226224707

Centisome position: 74.88

GC content: 45.61

Gene sequence:

>888_bases
ATGGAGAAAAAAGTTGGTACAGATCGTGTAAAACGTGGTATGGCGCAAATGCAAAAAGGTGGCGTCATTATGGACGTAGT
TAATGCTGAACAAGCAAAAATCGCAGAAGAAGCTGGCGCTGTTGCCGTTATGGCGCTTGAACGGGTTCCTTCCGATATTC
GTGCAGCTGGTGGTGTCGCTCGTATGGCCGATCCTCGTATTGTCGAAGAAGTAATGAACGCTGTTTCTATCCCCGTAATG
GCGAAAGCACGTATTGGTCATATTACAGAAGCTCGCGTCCTTGAAGCAATGGGTGTTGATTATATCGACGAAAGTGAAGT
ATTAACACCAGCCGATGATGAATTCCATTTATTAAAATCAGATTTCACTGTCCCATTCGTGTGTGGTTGTCGTGATATTG
GTGAAGCACTCCGCCGTATTGGTGAAGGGGCTGCCATGCTTCGTACAAAAGGAGAACCCGGAACAGGCAATATCGTTGAA
GCTGTCCGCCACATGCGCCAAGTAAACGGTCAAATCCGCCAAATTGCGGGAATGACGGATGATGAGTTAATGGTTGCCGC
TAAAAACTTCGGTGCTCCATATGAATTAATCAAAGAAATTAAAACACTTGGCAAACTTCCGGTCGTTAATTTTGCTGCTG
GTGGTGTTGCGACTCCCGCAGATGCCGCATTAATGATGGAACTTGGAGCAGACGGCGTTTTCGTTGGTTCTGGTATTTTC
AAATCAGATAACCCTGCCAAATTTGCCAGTGCGATTGTCCAAGCTACCACTTACTATACTGACTATGAGCTAATCGGAAA
ACTTTCCAAAGAGCTAGGTTCCCCGATGAAAGGAATCGAAATGTCTCGCCTTAACCCAGAAGACAGAATGCAAGATCGGA
GCATTTAA

Upstream 100 bases:

>100_bases
GATGGAGAAAACAACATCCAATTGGCTGTTTTTACGAAATGGCTTTTAGCTTATCATAATAATCAGGTATTTTCAATTAA
CTTTGATGGAGGTTATTAGT

Downstream 100 bases:

>100_bases
TATGAAAAAAATTGGAGTCCTTGCAATTCAAGGTGCAGTTGATGAACATATCCAAATGATTGAATCAGCCGGTGCTCTTG
CTTTTAAAGTAAAGCATTCA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEKKVGTDRVKRGMAQMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVARMADPRIVEEVMNAVSIPVM
AKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKSDFTVPFVCGCRDIGEALRRIGEGAAMLRTKGEPGTGNIVE
AVRHMRQVNGQIRQIAGMTDDELMVAAKNFGAPYELIKEIKTLGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSDNPAKFASAIVQATTYYTDYELIGKLSKELGSPMKGIEMSRLNPEDRMQDRSI

Sequences:

>Translated_295_residues
MEKKVGTDRVKRGMAQMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVARMADPRIVEEVMNAVSIPVM
AKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKSDFTVPFVCGCRDIGEALRRIGEGAAMLRTKGEPGTGNIVE
AVRHMRQVNGQIRQIAGMTDDELMVAAKNFGAPYELIKEIKTLGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSDNPAKFASAIVQATTYYTDYELIGKLSKELGSPMKGIEMSRLNPEDRMQDRSI
>Mature_295_residues
MEKKVGTDRVKRGMAQMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVARMADPRIVEEVMNAVSIPVM
AKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKSDFTVPFVCGCRDIGEALRRIGEGAAMLRTKGEPGTGNIVE
AVRHMRQVNGQIRQIAGMTDDELMVAAKNFGAPYELIKEIKTLGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
KSDNPAKFASAIVQATTYYTDYELIGKLSKELGSPMKGIEMSRLNPEDRMQDRSI

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring [H]

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=278, Percent_Identity=57.5539568345324, Blast_Score=340, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6323996, Length=279, Percent_Identity=59.8566308243728, Blast_Score=339, Evalue=4e-94,
Organism=Saccharomyces cerevisiae, GI6321049, Length=279, Percent_Identity=59.8566308243728, Blast_Score=338, Evalue=4e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852 [H]

Pfam domain/function: PF01680 SOR_SNZ [H]

EC number: NA

Molecular weight: Translated: 31673; Mature: 31673

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS01235 PDXS_SNZ_1 ; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKVGTDRVKRGMAQMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVA
CCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHHHCCHH
RMADPRIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKS
HHCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHC
DFTVPFVCGCRDIGEALRRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNGQIRQIAGMTD
CCCCEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DELMVAAKNFGAPYELIKEIKTLGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
CHHEEEHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSDNPAKFASAIVQATTYYTDYELIGKLSKELGSPMKGIEMSRLNPEDRMQDRSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHCCCC
>Mature Secondary Structure
MEKKVGTDRVKRGMAQMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPSDIRAAGGVA
CCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHHHCCHH
RMADPRIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADDEFHLLKS
HHCCHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHC
DFTVPFVCGCRDIGEALRRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNGQIRQIAGMTD
CCCCEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
DELMVAAKNFGAPYELIKEIKTLGKLPVVNFAAGGVATPADAALMMELGADGVFVGSGIF
CHHEEEHHHCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSDNPAKFASAIVQATTYYTDYELIGKLSKELGSPMKGIEMSRLNPEDRMQDRSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]