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The map label for this gene is ilvH

Identifier: 226224583

GI number: 226224583

Start: 2046665

End: 2047156

Strand: Direct

Name: ilvH

Synonym: Lm4b_01997

Alternate gene names: 226224583

Gene position: 2046665-2047156 (Clockwise)

Preceding gene: 226224582

Following gene: 226224584

Centisome position: 70.27

GC content: 44.31

Gene sequence:

>492_bases
ATGCGCCGAATCATTACCGCTACAGTAAACAACTCTTCTGGCGTGTTAAATCGTATCACTGGGGTTATCTCCAGACGCCA
ATACAATATTGATAGCATCTCTGTCGGCTGGACCGAAATCCCAAATGTTTCTCGGATTACCATCGTCGTCCATGTCGATT
CCTTATACGAAATCGAGCAAGTAACTAAACAACTCAATAAACAAATCGATGTGCTCAAAGTGAGCGATATTACTGACGAT
GCACACATCGAACGCGAACTAGCTTTACTTAAAATCAACTCCCCCGCTGCCTTACGATCTGAGCTAAACGCAGTCATCGA
ACCATTTCGCGCCACTGTTATTGATGTCGGCACGAAAAATGTCGTCATTCAAGTAACTGGCACAAGTGAAAAAATCGATG
CTTTCGTTGACACAGTTCGCCCGTATGGTATTAAGCAAATGGCGAGGACCGGCGTCACAGGCTTTACAAGAAGCCCTAAA
AAAATGGGTTAA

Upstream 100 bases:

>100_bases
TGGACCGATTGTCATTGACGTTCATGTAGCCAAAGATGAGCTAGTACTTCCAATGGTTCCAAGCGGCAAACCAAATCACC
AAATGGAAGGAGTGGAATAA

Downstream 100 bases:

>100_bases
AAATCATTTACTACAGAGCAGTCTCTTGCTTTGCTAGCATCAGAACAGCACATCGCTATTCTGAAATATAAAAAGAAATT
AGTTGGAGGTTAGGAAAAAT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRRIITATVNNSSGVLNRITGVISRRQYNIDSISVGWTEIPNVSRITIVVHVDSLYEIEQVTKQLNKQIDVLKVSDITDD
AHIERELALLKINSPAALRSELNAVIEPFRATVIDVGTKNVVIQVTGTSEKIDAFVDTVRPYGIKQMARTGVTGFTRSPK
KMG

Sequences:

>Translated_163_residues
MRRIITATVNNSSGVLNRITGVISRRQYNIDSISVGWTEIPNVSRITIVVHVDSLYEIEQVTKQLNKQIDVLKVSDITDD
AHIERELALLKINSPAALRSELNAVIEPFRATVIDVGTKNVVIQVTGTSEKIDAFVDTVRPYGIKQMARTGVTGFTRSPK
KMG
>Mature_163_residues
MRRIITATVNNSSGVLNRITGVISRRQYNIDSISVGWTEIPNVSRITIVVHVDSLYEIEQVTKQLNKQIDVLKVSDITDD
AHIERELALLKINSPAALRSELNAVIEPFRATVIDVGTKNVVIQVTGTSEKIDAFVDTVRPYGIKQMARTGVTGFTRSPK
KMG

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=42.3312883435583, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18047; Mature: 18047

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIITATVNNSSGVLNRITGVISRRQYNIDSISVGWTEIPNVSRITIVVHVDSLYEIEQ
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEECCHHHHHH
VTKQLNKQIDVLKVSDITDDAHIERELALLKINSPAALRSELNAVIEPFRATVIDVGTKN
HHHHHHCCCCEEEECCCCCCHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCE
VVIQVTGTSEKIDAFVDTVRPYGIKQMARTGVTGFTRSPKKMG
EEEEEECCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRIITATVNNSSGVLNRITGVISRRQYNIDSISVGWTEIPNVSRITIVVHVDSLYEIEQ
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEECCHHHHHH
VTKQLNKQIDVLKVSDITDDAHIERELALLKINSPAALRSELNAVIEPFRATVIDVGTKN
HHHHHHCCCCEEEECCCCCCHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCE
VVIQVTGTSEKIDAFVDTVRPYGIKQMARTGVTGFTRSPKKMG
EEEEEECCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]