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The map label for this gene is ytxM [H]

Identifier: 226224277

GI number: 226224277

Start: 1714223

End: 1715050

Strand: Reverse

Name: ytxM [H]

Synonym: Lm4b_01687

Alternate gene names: 226224277

Gene position: 1715050-1714223 (Counterclockwise)

Preceding gene: 226224278

Following gene: 226224276

Centisome position: 58.88

GC content: 40.82

Gene sequence:

>828_bases
ATGCTAGTAAACGGTCGACATTATCATCTGACAACTGCTATAAGTGGAGAAAAGCCAGCTTTACTGATGTTACATGGTTT
TACTGGAACAAGCGAAACATTTCAAGATAGTATTTCAGGTTTGAAAGAACATTTTAATATTATTGCGCCAGATTTACTTG
GGCACGGAAATACCGCAAGCCCAGAAGAAATATCGCCTTACACAATGGAAAATATTTGCGAGGATTTAGCTGGAATTTTA
CATCAATTAAATATCAGTAGATGTTTTGTACTTGGCTATTCGATGGGCGGGCGGGTCGCGACTGCGTTTGCAGCAACCTT
TCCAAAAAGGGTGCGTGGACTTATTTTAGTTAGTAGCTCTCCTGGCCTTGAACAAGCAGATATCCGAGAAAGCCGTGTTG
CGGCTGATAATCGTTTGGCAGACTGGATTGAAGAAGAGGGCTTGGTGCCTTTTGTGGACTACTGGGAAAATTTAGCTTTG
TTTGCTTCACAAAAAGTTTTGTCTCCTGAAATGAAAAGAAGAATTAGGTCAGAACGGCTATCGCAAAACTCGCATGGTTT
AGCAATGAGTCTACGTGGGATGGGGACCGGAAAACAACCATCTTACTGGAACTGTTTAGCGAACTTTACTTTTCCAGTGC
TACTCATTACCGGTGCTTTAGATGAGAAGTTTGAAAAAATCGCGCAGGAAATGCATCAACTTTTACCAAATAGTACGCAT
GTTTCAATTCAAGAAGCGGGGCATGCAGTTTATTTAGAACAACCAAACAGCTTTTCAAGTCAGCTTAATTACTGGCTGGA
AGATATTTTGAAGGAGGAAGAAAAATGA

Upstream 100 bases:

>100_bases
TTGGATATTATTGAAGTGAAAACAAATCGTCATGAAAATAAAGCAAATCATCAAGCACTTTGGGTTAAAATTGCGGACGC
GTTAAAGGCATTAGATTAAT

Downstream 100 bases:

>100_bases
GTTTTAATTGGCAAACAGAAAAAGTATATGAGGAAATCAAATATGAAAGTTACGAAGGAATCGCGAAAATTACGATTAAT
CGTCCAGAAGTACATAATGC

Product: prolyl aminopetidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MLVNGRHYHLTTAISGEKPALLMLHGFTGTSETFQDSISGLKEHFNIIAPDLLGHGNTASPEEISPYTMENICEDLAGIL
HQLNISRCFVLGYSMGGRVATAFAATFPKRVRGLILVSSSPGLEQADIRESRVAADNRLADWIEEEGLVPFVDYWENLAL
FASQKVLSPEMKRRIRSERLSQNSHGLAMSLRGMGTGKQPSYWNCLANFTFPVLLITGALDEKFEKIAQEMHQLLPNSTH
VSIQEAGHAVYLEQPNSFSSQLNYWLEDILKEEEK

Sequences:

>Translated_275_residues
MLVNGRHYHLTTAISGEKPALLMLHGFTGTSETFQDSISGLKEHFNIIAPDLLGHGNTASPEEISPYTMENICEDLAGIL
HQLNISRCFVLGYSMGGRVATAFAATFPKRVRGLILVSSSPGLEQADIRESRVAADNRLADWIEEEGLVPFVDYWENLAL
FASQKVLSPEMKRRIRSERLSQNSHGLAMSLRGMGTGKQPSYWNCLANFTFPVLLITGALDEKFEKIAQEMHQLLPNSTH
VSIQEAGHAVYLEQPNSFSSQLNYWLEDILKEEEK
>Mature_275_residues
MLVNGRHYHLTTAISGEKPALLMLHGFTGTSETFQDSISGLKEHFNIIAPDLLGHGNTASPEEISPYTMENICEDLAGIL
HQLNISRCFVLGYSMGGRVATAFAATFPKRVRGLILVSSSPGLEQADIRESRVAADNRLADWIEEEGLVPFVDYWENLAL
FASQKVLSPEMKRRIRSERLSQNSHGLAMSLRGMGTGKQPSYWNCLANFTFPVLLITGALDEKFEKIAQEMHQLLPNSTH
VSIQEAGHAVYLEQPNSFSSQLNYWLEDILKEEEK

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=115, Percent_Identity=29.5652173913043, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI218777840, Length=118, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI13376164, Length=118, Percent_Identity=26.271186440678, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1788598, Length=244, Percent_Identity=29.5081967213115, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324392, Length=241, Percent_Identity=25.3112033195021, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR022485 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30679; Mature: 30679

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVNGRHYHLTTAISGEKPALLMLHGFTGTSETFQDSISGLKEHFNIIAPDLLGHGNTAS
CCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCC
PEEISPYTMENICEDLAGILHQLNISRCFVLGYSMGGRVATAFAATFPKRVRGLILVSSS
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCEEEEEECC
PGLEQADIRESRVAADNRLADWIEEEGLVPFVDYWENLALFASQKVLSPEMKRRIRSERL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SQNSHGLAMSLRGMGTGKQPSYWNCLANFTFPVLLITGALDEKFEKIAQEMHQLLPNSTH
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCE
VSIQEAGHAVYLEQPNSFSSQLNYWLEDILKEEEK
EEHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVNGRHYHLTTAISGEKPALLMLHGFTGTSETFQDSISGLKEHFNIIAPDLLGHGNTAS
CCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCC
PEEISPYTMENICEDLAGILHQLNISRCFVLGYSMGGRVATAFAATFPKRVRGLILVSSS
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCEEEEEECC
PGLEQADIRESRVAADNRLADWIEEEGLVPFVDYWENLALFASQKVLSPEMKRRIRSERL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
SQNSHGLAMSLRGMGTGKQPSYWNCLANFTFPVLLITGALDEKFEKIAQEMHQLLPNSTH
CCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCE
VSIQEAGHAVYLEQPNSFSSQLNYWLEDILKEEEK
EEHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8566759; 9387221; 9384377 [H]