Click here to switch to the map view.

The map label for this gene is guaA [H]

Identifier: 226224240

GI number: 226224240

Start: 1667349

End: 1667930

Strand: Reverse

Name: guaA [H]

Synonym: Lm4b_01650

Alternate gene names: 226224240

Gene position: 1667930-1667349 (Counterclockwise)

Preceding gene: 226224241

Following gene: 226224239

Centisome position: 57.26

GC content: 38.32

Gene sequence:

>582_bases
TTGTCTGAAGAATTACGTTGCCCTTGGTCGATTAATGACCCGTTTGAACTAGAATATCATGATACAGAATGGTGTGTTCC
GAGTAAAGACGACACATATTTATTTGAAATGCTCAATTTAGAGGGAGCACAAGCTGGACTCTCATGGAGATTAATTTTAC
ATAAAAGAAAAGCCTATCAAGAAGCTTTTTTTCACTTTGATATTGATAAATGTGCACGCCTAACAGACGATGAGCTGGCG
ACGATTGTCGAAGAAGCGGCTATTGTAAAGAATCGCCTTAAAGTGAAAGCAGTTCGTACAAATGCCCTAGCTACGCAAAA
AGTCCAAGCTGAATTCGGCTCATTTGCAAACTATATTTGGGGTTTTACGAATAATGACCGTATTATTAATGAATGGCAAG
GCATGGGAGAGGTCCCTGCAAGCACAGAACTATCAGAAAAAATCAGTAAAGATTTAAAGAAACGTGGTTTTAAGTTTGTT
GGCCCTGTAATTGTGTATTCTTATTTACAAGCTATTGGGATTTTGGATGACCATTTACGTTCATGCCCATTTCATACATT
TAATAGGGAGGCGACGAAATGA

Upstream 100 bases:

>100_bases
TCAGTGGAAAGAGAAACGACTAATTTGGAGTTGCGTCGGACTATTTGTGGCTGTTTTGATCAGTGTGTATTACATTTTAA
CTATATAGGAGGAACTCGCT

Downstream 100 bases:

>100_bases
TTCCAGCGAAATTAAAACAAGGGGATGAAATTCGGATTATTGCACCAAGTCGTTCTATCGGTATTATGGCTGACAATCAA
GTGGAAATTGCCGTTAAGCG

Product: dna-3-methyladenine glycosidase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSEELRCPWSINDPFELEYHDTEWCVPSKDDTYLFEMLNLEGAQAGLSWRLILHKRKAYQEAFFHFDIDKCARLTDDELA
TIVEEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIWGFTNNDRIINEWQGMGEVPASTELSEKISKDLKKRGFKFV
GPVIVYSYLQAIGILDDHLRSCPFHTFNREATK

Sequences:

>Translated_193_residues
MSEELRCPWSINDPFELEYHDTEWCVPSKDDTYLFEMLNLEGAQAGLSWRLILHKRKAYQEAFFHFDIDKCARLTDDELA
TIVEEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIWGFTNNDRIINEWQGMGEVPASTELSEKISKDLKKRGFKFV
GPVIVYSYLQAIGILDDHLRSCPFHTFNREATK
>Mature_192_residues
SEELRCPWSINDPFELEYHDTEWCVPSKDDTYLFEMLNLEGAQAGLSWRLILHKRKAYQEAFFHFDIDKCARLTDDELAT
IVEEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIWGFTNNDRIINEWQGMGEVPASTELSEKISKDLKKRGFKFVG
PVIVYSYLQAIGILDDHLRSCPFHTFNREATK

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=184, Percent_Identity=40.7608695652174, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 22303; Mature: 22171

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEELRCPWSINDPFELEYHDTEWCVPSKDDTYLFEMLNLEGAQAGLSWRLILHKRKAYQ
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EAFFHFDIDKCARLTDDELATIVEEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIW
HHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHC
GFTNNDRIINEWQGMGEVPASTELSEKISKDLKKRGFKFVGPVIVYSYLQAIGILDDHLR
CCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SCPFHTFNREATK
HCCCCCCCCCCCC
>Mature Secondary Structure 
SEELRCPWSINDPFELEYHDTEWCVPSKDDTYLFEMLNLEGAQAGLSWRLILHKRKAYQ
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
EAFFHFDIDKCARLTDDELATIVEEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIW
HHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHC
GFTNNDRIINEWQGMGEVPASTELSEKISKDLKKRGFKFVGPVIVYSYLQAIGILDDHLR
CCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
SCPFHTFNREATK
HCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]