Click here to switch to the map view.

The map label for this gene is ykvY [H]

Identifier: 226224179

GI number: 226224179

Start: 1603790

End: 1604887

Strand: Direct

Name: ykvY [H]

Synonym: Lm4b_01589

Alternate gene names: 226224179

Gene position: 1603790-1604887 (Clockwise)

Preceding gene: 226224122

Following gene: 226224181

Centisome position: 55.06

GC content: 40.98

Gene sequence:

>1098_bases
ATGGAAAAAAATATCGATGTCTTACAAAATTGGCTAAAAGACCAAGGTGCTGAGGTGGCATTTTTAACAGATCCAGAGAA
CATCGCTTATTTCTCGGGTTATCATAGTGAGCCTCATGAGCGCGTGCTTGGCTTAGCAGTTTTCCCAGATAGTGAACCGT
TTTTATTTACGCCCGCTCTTGAAGTAGAAGATGTGCGCGGCGGTGACTGGACACACCCTGCATACGGATATAACGATACC
GAGAATCCTTTCACCATCATTGCAGACGAAATCAAAAAACGAGTTGCAAATCCAAGCAAATTTGCTATTGAGAAAAAACA
TATGAGCGTAGATCGCTACGAACAATTAGGTGGATTATTCTCCGGCAGCTCTTTCATTCCGATTGAACACAAAATTGAGC
AAATTCGTCTGATTAAAACCGAAGCCGAACTAAAAATATTAAAAGAAGCAGCCTTATTAGCCGATTACGCCGTACAAGTT
GGTGTAAACGAAATCGCAGAAGGTAAAACAGAAGCAGAAATCGTGGCGAAAATCGAATACGAAATGAAGAAAAAAGGCGT
AACTGCCATGTCTTTCGATACAATGGTCCTTACTGGTAAAAACGGTGCCCTGCCACATGGTACTCCAGGCGAAACAAAAA
TCAAAAAAGGCGATTTAGTTTTATTTGATTTAGGCGTTGTCCATAAAGGCTATTGCTCTGATATTACACGCACAGTAGCT
TTTGGAGATATTTCCGATGAACAGAAAAAGATTTACGACACTGTTTTAGAAGCGCAAATTGCCGCTGTCGAAAAAGTAAA
AGCCGGCGTAAAAGCAAGCGAAATTGATTTAACTGCTAGAAATATTATTCGTGAAGCAGGTTACAGTGATTATTTCCCAC
ATCGTCTTGGTCACGGTCTTGGCGCGAGTGTCCATGAATTCCCTTCGATTACAGAAACGAACAATATGGAACTGCAAGAA
AATATGGTATTTACGATTGAACCAGGTATTTATGTTCCCGGTGTTGCCGGCGTTCGTATAGAAGATGACCTCGTTGTCAC
AAAAGACGGCGTGCAAGTATTAACGGAATTCCCAAAAACTTTACAAGTAATCGACTAA

Upstream 100 bases:

>100_bases
CTACTATATAACACCTCGTAAACTAAGAGGTGTTTATTAGCAAAATAATTCCTTCGCATGTTATCATGAAATAGAAATCA
ATTGGAAAGAAGGTACAATT

Downstream 100 bases:

>100_bases
CAAGAAAAGCGAACTTTCCTTTGAGAAAGTTCGCTTTTTTTATTAAATTAATTCTTTGCTATCCGTATAGGGTAAATCAA
GTGAATCTGCAACAGCCTTG

Product: X-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPDSEPFLFTPALEVEDVRGGDWTHPAYGYNDT
ENPFTIIADEIKKRVANPSKFAIEKKHMSVDRYEQLGGLFSGSSFIPIEHKIEQIRLIKTEAELKILKEAALLADYAVQV
GVNEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
FGDISDEQKKIYDTVLEAQIAAVEKVKAGVKASEIDLTARNIIREAGYSDYFPHRLGHGLGASVHEFPSITETNNMELQE
NMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVID

Sequences:

>Translated_365_residues
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPDSEPFLFTPALEVEDVRGGDWTHPAYGYNDT
ENPFTIIADEIKKRVANPSKFAIEKKHMSVDRYEQLGGLFSGSSFIPIEHKIEQIRLIKTEAELKILKEAALLADYAVQV
GVNEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
FGDISDEQKKIYDTVLEAQIAAVEKVKAGVKASEIDLTARNIIREAGYSDYFPHRLGHGLGASVHEFPSITETNNMELQE
NMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVID
>Mature_365_residues
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPDSEPFLFTPALEVEDVRGGDWTHPAYGYNDT
ENPFTIIADEIKKRVANPSKFAIEKKHMSVDRYEQLGGLFSGSSFIPIEHKIEQIRLIKTEAELKILKEAALLADYAVQV
GVNEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
FGDISDEQKKIYDTVLEAQIAAVEKVKAGVKASEIDLTARNIIREAGYSDYFPHRLGHGLGASVHEFPSITETNNMELQE
NMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVID

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=268, Percent_Identity=31.7164179104478, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI149589008, Length=298, Percent_Identity=28.5234899328859, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI260593665, Length=298, Percent_Identity=28.5234899328859, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260593663, Length=249, Percent_Identity=29.3172690763052, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI40385867, Length=246, Percent_Identity=25.609756097561, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI93141226, Length=193, Percent_Identity=33.160621761658, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI264681563, Length=195, Percent_Identity=32.8205128205128, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI164420681, Length=245, Percent_Identity=26.9387755102041, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI264681565, Length=192, Percent_Identity=31.7708333333333, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788728, Length=232, Percent_Identity=41.3793103448276, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789275, Length=256, Percent_Identity=30.46875, Blast_Score=121, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17508215, Length=299, Percent_Identity=25.0836120401338, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71989583, Length=258, Percent_Identity=25.968992248062, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=211, Percent_Identity=32.2274881516588, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=28.2945736434109, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321118, Length=297, Percent_Identity=26.2626262626263, Blast_Score=101, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=26.8774703557312, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=25.1012145748988, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322999, Length=250, Percent_Identity=26.8, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920384, Length=277, Percent_Identity=30.6859205776173, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI21357079, Length=298, Percent_Identity=28.5234899328859, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21355531, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17137632, Length=242, Percent_Identity=28.5123966942149, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161078230, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357287, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40389; Mature: 40389

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPDSEPFLFTPAL
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHEEEEEECCCCCCEEEECCC
EVEDVRGGDWTHPAYGYNDTENPFTIIADEIKKRVANPSKFAIEKKHMSVDRYEQLGGLF
CEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHHEEEHHHCCHHHHHHHCCCC
SGSSFIPIEHKIEQIRLIKTEAELKILKEAALLADYAVQVGVNEIAEGKTEAEIVAKIEY
CCCCCCCHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHEEEHHHH
EMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
HHHHCCCEEEEECEEEEECCCCCCCCCCCCCCEEECCCEEEEECCCCCCCHHHHHHHHEE
FGDISDEQKKIYDTVLEAQIAAVEKVKAGVKASEIDLTARNIIREAGYSDYFPHRLGHGL
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
GASVHEFPSITETNNMELQENMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKT
CCCHHHCCCCCCCCCCEEECCEEEEECCCEECCCCCCEEEECCEEEECCHHHHHHHCCHH
LQVID
HEECC
>Mature Secondary Structure
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPDSEPFLFTPAL
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHEEEEEECCCCCCEEEECCC
EVEDVRGGDWTHPAYGYNDTENPFTIIADEIKKRVANPSKFAIEKKHMSVDRYEQLGGLF
CEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHHEEEHHHCCHHHHHHHCCCC
SGSSFIPIEHKIEQIRLIKTEAELKILKEAALLADYAVQVGVNEIAEGKTEAEIVAKIEY
CCCCCCCHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHEEEHHHH
EMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
HHHHCCCEEEEECEEEEECCCCCCCCCCCCCCEEECCCEEEEECCCCCCCHHHHHHHHEE
FGDISDEQKKIYDTVLEAQIAAVEKVKAGVKASEIDLTARNIIREAGYSDYFPHRLGHGL
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
GASVHEFPSITETNNMELQENMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKT
CCCHHHCCCCCCCCCCEEECCEEEEECCCEECCCCCCEEEECCEEEECCHHHHHHHCCHH
LQVID
HEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]