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The map label for this gene is prmA

Identifier: 226224072

GI number: 226224072

Start: 1486712

End: 1487656

Strand: Reverse

Name: prmA

Synonym: Lm4b_01481

Alternate gene names: 226224072

Gene position: 1487656-1486712 (Counterclockwise)

Preceding gene: 226224073

Following gene: 226224071

Centisome position: 51.07

GC content: 38.94

Gene sequence:

>945_bases
ATGGAATGGTCAGAAGTAGAAGTCCATACAACAAACGAAGCTGTAGAACCAGTAGCTAATGTTTTGACAGAATTTGGTGC
AGCAGGAGTATCCATTGAAGATGTTGCTGATTTTTTACGTGAACGAGAAGACAAATTTGGAGAAATATATGCACTAAGAC
GAGAAGATTATCCAGAAGACGGCGTTATTATTAAAGCTTACTTCTTAAAGACAACAGAATTTGTAGAGCAAATTCCAGAA
ATTGAACAAACATTGAAGAATCTGTCTACTTTTGATATTCCGCTAGGTAATTTCCAATTTGTCGTTAATGATGTGGACGA
CGAGGAGTGGGCTACCGCATGGAAGAAGTATTATCATCCAGTTCAAATCACTGACAGGATCACGATTGTACCAAGTTGGG
AATCATACACCCCATCTGCTAACGAAATAATCATTGAGCTAGATCCAGGAATGGCTTTTGGGACAGGAACACATCCGACA
ACTCAGCTATGTATCCGCGCACTGAGCGATTATTTACAACCAGGAGATGAAGTGATTGATGTTGGGACTGGTTCTGGCGT
CTTAAGTATTGCCAGTGCTAAATTAGGTGCAAAATCTATTTTAGCAACAGACCTCGACGAAATCGCCACTCGTGCAGCAG
AAGAAAATATTACTTTAAATAAAACTGAACACATTATTACTGTCAAACAAAATAATCTACTTCAAGATATTAATAAAACA
GACGTGGATATTGTTGTTGCGAACATTTTAGCAGAAGTTATTTTGCTTTTCCCTGAGGATGTTTATAGAGCACTCAAACC
AGGCGGAATTTTCATTGCTTCCGGGATTATTGAAGACAAAGCGAAAGTAGTCGAAGAAGCACTTAAAAAGGCTGGGCTTG
TTATTGAAAAAATGGAGCAACAAGGGGACTGGGTTGCGATTATTTCCAAACGAGGAGTGGAATAA

Upstream 100 bases:

>100_bases
AAATGAAACGAGCTTTTAAAGGCGATTGATGAACGTAGAGGTCGATAGTTGTGCGAGAAGCAACCATCGACCTTTTCTAC
ATACAAAAGGAGTGTTAAAA

Downstream 100 bases:

>100_bases
ATGCAACGTTATTTTGTAACAAATGAGCTAGAGAATGATAACGAAACACTATCCATTACTGGAGAAAACTTCCATCATAT
TACTCGTGTTATGCGAATGA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPEDGVIIKAYFLKTTEFVEQIPE
IEQTLKNLSTFDIPLGNFQFVVNDVDDEEWATAWKKYYHPVQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPT
TQLCIRALSDYLQPGDEVIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKT
DVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKKAGLVIEKMEQQGDWVAIISKRGVE

Sequences:

>Translated_314_residues
MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPEDGVIIKAYFLKTTEFVEQIPE
IEQTLKNLSTFDIPLGNFQFVVNDVDDEEWATAWKKYYHPVQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPT
TQLCIRALSDYLQPGDEVIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKT
DVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKKAGLVIEKMEQQGDWVAIISKRGVE
>Mature_314_residues
MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPEDGVIIKAYFLKTTEFVEQIPE
IEQTLKNLSTFDIPLGNFQFVVNDVDDEEWATAWKKYYHPVQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPT
TQLCIRALSDYLQPGDEVIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKT
DVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKKAGLVIEKMEQQGDWVAIISKRGVE

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=252, Percent_Identity=31.3492063492063, Blast_Score=107, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34842; Mature: 34842

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPED
CCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCC
GVIIKAYFLKTTEFVEQIPEIEQTLKNLSTFDIPLGNFQFVVNDVDDEEWATAWKKYYHP
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCC
VQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPTTQLCIRALSDYLQPGDEVID
EEEECEEEEEECCCCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCCCEEE
VGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKT
ECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCHHHHCCCC
DVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKKAGLVIEKMEQ
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCHHHHHHHH
QGDWVAIISKRGVE
CCCEEEEEECCCCC
>Mature Secondary Structure
MEWSEVEVHTTNEAVEPVANVLTEFGAAGVSIEDVADFLREREDKFGEIYALRREDYPED
CCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCC
GVIIKAYFLKTTEFVEQIPEIEQTLKNLSTFDIPLGNFQFVVNDVDDEEWATAWKKYYHP
CEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCC
VQITDRITIVPSWESYTPSANEIIIELDPGMAFGTGTHPTTQLCIRALSDYLQPGDEVID
EEEECEEEEEECCCCCCCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHHHHCCCCCEEE
VGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTEHIITVKQNNLLQDINKT
ECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCHHHHCCCC
DVDIVVANILAEVILLFPEDVYRALKPGGIFIASGIIEDKAKVVEEALKKAGLVIEKMEQ
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCHHHHHHHH
QGDWVAIISKRGVE
CCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]