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The map label for this gene is opuCB

Identifier: 226224028

GI number: 226224028

Start: 1442081

End: 1442737

Strand: Reverse

Name: opuCB

Synonym: Lm4b_01436

Alternate gene names: 226224028

Gene position: 1442737-1442081 (Counterclockwise)

Preceding gene: 226224029

Following gene: 226224027

Centisome position: 49.53

GC content: 39.42

Gene sequence:

>657_bases
ATGGACGCAATTGTTACATTTTTCCAAGAAAACGGCCATAACTTGCTTGTTCAAACATGGCAACATTTATTTATCTCCCT
ATCTGCTGTTATTTTAGGTATTGCGGTTGCAGTACCAACTGGGATTTTACTTACACGCTCACCAAAAGTAGCAAATTTTG
TAATTGGTGTTGTTAGTGTTTTGCAAACCGTTCCTTCTCTTGCCATTTTGGCGTTTATTATTCCGTTTCTTGGTGTTGGT
ACTTTACCAGCGATTATTGCGTTATTTATTTACGCACTTTTACCAATTTTACGAAACACGTTTATTGGTGTTCGAGGAGT
CGACAAAAATTTAATCGAATCTGGTCGCGGCATGGGGATGACGAATTGGCAACTAATTATTAATGTCGAAATTCCTAACT
CCATTTCCGTTATTATGGCTGGTATTCGTTTATCTGCAGTATATGTTATCGCTTGGGCAACGCTTGCTTCTTACATTGGA
GCTGGTGGACTAGGAGACTTTATTTTTAATGGTTTAAACTTATACCGCCCCGATTTAATTCTTGGTGGGGCAATTCCTGT
TACCATTTTAGCCCTTGTAGTAGAATTCGCGCTTGGAAAATTAGAATATCGTCTAACTCCAAAAGCCATCCGCGAAGCTC
GGGAAGGGGGAGAATAA

Upstream 100 bases:

>100_bases
TGACTCCATTTGGGGTACGGTAGAAGATGCGACAGAAAATCAGGAGGAACAGGCGGATTCCAAAACGACAGAACCAGAAA
TGAAGCAGGAGGGATAAGCT

Downstream 100 bases:

>100_bases
CATGAAGAAAAAATTTATCGCGTTATTCAGCGTATTACTACTAACTAGTTCTCTTTTCTTATCTAGCTGTTCTTTACCAG
GACTTGGAGGCAGTTCCAAA

Product: glycine betaine/carnitine/choline ABC transporter (membrane protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MDAIVTFFQENGHNLLVQTWQHLFISLSAVILGIAVAVPTGILLTRSPKVANFVIGVVSVLQTVPSLAILAFIIPFLGVG
TLPAIIALFIYALLPILRNTFIGVRGVDKNLIESGRGMGMTNWQLIINVEIPNSISVIMAGIRLSAVYVIAWATLASYIG
AGGLGDFIFNGLNLYRPDLILGGAIPVTILALVVEFALGKLEYRLTPKAIREAREGGE

Sequences:

>Translated_218_residues
MDAIVTFFQENGHNLLVQTWQHLFISLSAVILGIAVAVPTGILLTRSPKVANFVIGVVSVLQTVPSLAILAFIIPFLGVG
TLPAIIALFIYALLPILRNTFIGVRGVDKNLIESGRGMGMTNWQLIINVEIPNSISVIMAGIRLSAVYVIAWATLASYIG
AGGLGDFIFNGLNLYRPDLILGGAIPVTILALVVEFALGKLEYRLTPKAIREAREGGE
>Mature_218_residues
MDAIVTFFQENGHNLLVQTWQHLFISLSAVILGIAVAVPTGILLTRSPKVANFVIGVVSVLQTVPSLAILAFIIPFLGVG
TLPAIIALFIYALLPILRNTFIGVRGVDKNLIESGRGMGMTNWQLIINVEIPNSISVIMAGIRLSAVYVIAWATLASYIG
AGGLGDFIFNGLNLYRPDLILGGAIPVTILALVVEFALGKLEYRLTPKAIREAREGGE

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788451, Length=191, Percent_Identity=34.5549738219895, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788449, Length=207, Percent_Identity=36.7149758454106, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789033, Length=185, Percent_Identity=30.8108108108108, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786564, Length=195, Percent_Identity=28.7179487179487, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23351; Mature: 23351

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIVTFFQENGHNLLVQTWQHLFISLSAVILGIAVAVPTGILLTRSPKVANFVIGVVSV
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
LQTVPSLAILAFIIPFLGVGTLPAIIALFIYALLPILRNTFIGVRGVDKNLIESGRGMGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
TNWQLIINVEIPNSISVIMAGIRLSAVYVIAWATLASYIGAGGLGDFIFNGLNLYRPDLI
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEE
LGGAIPVTILALVVEFALGKLEYRLTPKAIREAREGGE
ECCHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCC
>Mature Secondary Structure
MDAIVTFFQENGHNLLVQTWQHLFISLSAVILGIAVAVPTGILLTRSPKVANFVIGVVSV
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
LQTVPSLAILAFIIPFLGVGTLPAIIALFIYALLPILRNTFIGVRGVDKNLIESGRGMGM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
TNWQLIINVEIPNSISVIMAGIRLSAVYVIAWATLASYIGAGGLGDFIFNGLNLYRPDLI
CCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEE
LGGAIPVTILALVVEFALGKLEYRLTPKAIREAREGGE
ECCHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]