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The map label for this gene is ftsK [H]

Identifier: 226223987

GI number: 226223987

Start: 1393852

End: 1396125

Strand: Direct

Name: ftsK [H]

Synonym: Lm4b_01395

Alternate gene names: 226223987

Gene position: 1393852-1396125 (Clockwise)

Preceding gene: 226223986

Following gene: 226223989

Centisome position: 47.85

GC content: 38.87

Gene sequence:

>2274_bases
ATGGCGACACAAAAGAAAAAAACGAGCGGACGTAAAAAATCGTCAACACGCTCAAAAAAGAAACAATCAGCCTCTTTTCG
TTTAGAAATAACAGGGGTTATTTTAATAGCAATAGGAGTTATCGGACTTTTACAATTAGGCTTTGTCGGTCGCGGTTTTT
TTGCTCTGGCTGAAATGTTTGTTGGTCTTTTAAGCTATGTATTACTTGCGGGTAGCGTGATACTTGGTGGGTACATGGTG
ATTAGAAGAAAAATGCCTCACTTATTTAGCAAAAGACTAGTCGGTATTTATCTTATTGTTTTAGGCTTTTTGACATATAT
ACATATGTATTTTATTATCCATAACTTAGGGGTAAATGCGTCCGTAGTTTCTAGTACATGGAAATTAGTTCTAGAAAATT
TATTTAGACCAAATCAAGTTGGTTTTGTTGGTGGGGGAATGATTGGGGCTGCAATTACCTCCGTTACGTATTTCTTATTA
GATCGTCTCGGAACAAACTTGATTGCTGCGCTACTAATTATCTATGGTTTTTCCCTTGTATCAGGTATTTCCATCCGCCA
ATTTTTCTCTAAAATTGCCGAATTTGTTCGTTACTTATTTGCAAAAGGCAAAGTTGCGACCGAAAAAGGCAAAGAAGTGA
AAGCGAAACGTGATAAAAAGAAAGCAGAGAAAATAGTTGAGGTTGAGCCTGATGAAGTACTAGATGTAGTAGACCCCGCG
CAAGAAGAAAAAGCGCCACCAATCATCTCTAACTTTAGCTCCAAAGTAGAACAAGAAAAAGCACCAGTCGAAGAAAAAAC
AACCAAACAAGAGCAAGATTTAGAAATGTTTCAGCAAGAATCGTTCGAAAATGAGATTTATCAATTGCCCCCCGTTGATA
TTTTAGCACCGGCTAAAGTAACGGATCAAAGTAAAGAATATGACCAAATTAAAGTAAACGCAAAAAAATTAGAAGATACC
TTTGAAAGCTTCGGAGTGAAAGCAAAAATCACCCAAGTTCATCTTGGCCCTGCAGTGACAAAATATGAAGTACAACCATC
TGTCGGTGTTAAAGTGAGCAAGATTGTTTCACTCAGTGATGATATAGCACTTGCTCTAGCAGCAAAAGATATTCGAATTG
AAGCGCCAATTCCGGGGAAATCTGCTATTGGAATCGAAGTAGCGAACCAAAATGTAGCCATGGTTTCTTTACGTGAAGTG
TTAGAAAACAACCCTAAAAACAATCCAGACGAGAAGCTTCAAATAGCACTTGGTCGTGATATTTCTGGAGAAGCAATGAT
GGCAAGTCTCGATAAGATGCCTCATTTACTCGTCGCAGGAGCAACTGGTAGCGGGAAATCTGTGTGTATTAATGGTATTA
TTACAAGCATTTTACTCCGTGCCAAACCACATGAAGTCAAAATGATGATGATTGATCCAAAAATGGTTGAGCTAAATGTC
TATAATGGCATTCCACACTTGCTCGCACCAGTTGTTACCAATCCTAAAAAAGCAGCCCAAGCATTGCAAAAAGTCGTTGC
GGAAATGGAACGGCGCTATGATTTATTTTCGCATACAGGTACTCGTAATATGCAAGGCTACAATGATTATGTAAAAAAAC
ATAATGAGCTGAACGAAGAAAAACAACCTGAATTGCCTTTTATTGTTGTAATTGTAGATGAGTTAGCTGACTTGATGATG
GTAGCTTCCAATGACGTAGAAGATGCGATTACTCGCCTTGCTCAAATGGCACGTGCTGCGGGAATACATTTAATTATCGC
AACACAGCGTCCATCAGTAGATGTTATAACCGGCGTAATTAAAGCGAATATCCCGTCTCGAATTGCTTTTGCCGTTTCAA
GTTCCATTGATTCAAGAACGATTCTTGATATGGGCGGAGCAGAGAAGTTACTTGGACGAGGCGATATGCTGTTACTTCCA
GTTGGCTCTAGTAAACCTACCCGAATTCAAGGCGCTTTTTTATCGGATGCAGAAGTAGAAGATGTAGTTAATTACGTTAT
TTCGCAACAAAAAGCACAATATAGCGAAGAAATGATTCCTGATGATATTCCAGAAGTCGAAGGAGAAGTAACGGATGAAT
TGTATCACGAAGCAGTGGAGCTTGTTGTAGAAATGCAGACAGCTTCCGTTTCGATGTTACAAAGAAAATTCCGTATTGGC
TATAATCGTGCAGCTAGGTTGATTGATGAAATGGAACAAAGAGGTGTAGTTGGACCTCACGAAGGAAGTAAACCAAGAAG
AGTAAATGTGGAAATTAATCCAGAGCATGAATAA

Upstream 100 bases:

>100_bases
AAGGAAACATTTGTTTGTATAATAGGGCTATAGTATGAGCGACAGAACGGATAGATGTGCTATAATAAAACAAGCAAAAA
AGGAATGGGTGGGACTTGAA

Downstream 100 bases:

>100_bases
AAAAAGGTTGCGATTTGTAGTCGCAACCCTTTTTTATAAAAGTAAATCTTGCTTTTGTGCTTGAATTTCTTTTTTACTAG
AAGCATATTTTGTTTGAGTT

Product: DNA translocase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 756

Protein sequence:

>757_residues
MATQKKKTSGRKKSSTRSKKKQSASFRLEITGVILIAIGVIGLLQLGFVGRGFFALAEMFVGLLSYVLLAGSVILGGYMV
IRRKMPHLFSKRLVGIYLIVLGFLTYIHMYFIIHNLGVNASVVSSTWKLVLENLFRPNQVGFVGGGMIGAAITSVTYFLL
DRLGTNLIAALLIIYGFSLVSGISIRQFFSKIAEFVRYLFAKGKVATEKGKEVKAKRDKKKAEKIVEVEPDEVLDVVDPA
QEEKAPPIISNFSSKVEQEKAPVEEKTTKQEQDLEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKLEDT
FESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREV
LENNPKNNPDEKLQIALGRDISGEAMMASLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVELNV
YNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKHNELNEEKQPELPFIVVIVDELADLMM
VASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLP
VGSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYSEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKFRIG
YNRAARLIDEMEQRGVVGPHEGSKPRRVNVEINPEHE

Sequences:

>Translated_757_residues
MATQKKKTSGRKKSSTRSKKKQSASFRLEITGVILIAIGVIGLLQLGFVGRGFFALAEMFVGLLSYVLLAGSVILGGYMV
IRRKMPHLFSKRLVGIYLIVLGFLTYIHMYFIIHNLGVNASVVSSTWKLVLENLFRPNQVGFVGGGMIGAAITSVTYFLL
DRLGTNLIAALLIIYGFSLVSGISIRQFFSKIAEFVRYLFAKGKVATEKGKEVKAKRDKKKAEKIVEVEPDEVLDVVDPA
QEEKAPPIISNFSSKVEQEKAPVEEKTTKQEQDLEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKLEDT
FESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREV
LENNPKNNPDEKLQIALGRDISGEAMMASLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVELNV
YNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKHNELNEEKQPELPFIVVIVDELADLMM
VASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLP
VGSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYSEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKFRIG
YNRAARLIDEMEQRGVVGPHEGSKPRRVNVEINPEHE
>Mature_756_residues
ATQKKKTSGRKKSSTRSKKKQSASFRLEITGVILIAIGVIGLLQLGFVGRGFFALAEMFVGLLSYVLLAGSVILGGYMVI
RRKMPHLFSKRLVGIYLIVLGFLTYIHMYFIIHNLGVNASVVSSTWKLVLENLFRPNQVGFVGGGMIGAAITSVTYFLLD
RLGTNLIAALLIIYGFSLVSGISIRQFFSKIAEFVRYLFAKGKVATEKGKEVKAKRDKKKAEKIVEVEPDEVLDVVDPAQ
EEKAPPIISNFSSKVEQEKAPVEEKTTKQEQDLEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKLEDTF
ESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREVL
ENNPKNNPDEKLQIALGRDISGEAMMASLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVELNVY
NGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKHNELNEEKQPELPFIVVIVDELADLMMV
ASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLPV
GSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYSEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKFRIGY
NRAARLIDEMEQRGVVGPHEGSKPRRVNVEINPEHE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=484, Percent_Identity=47.7272727272727, Blast_Score=411, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83438; Mature: 83307

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQKKKTSGRKKSSTRSKKKQSASFRLEITGVILIAIGVIGLLQLGFVGRGFFALAEMF
CCCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGLLSYVLLAGSVILGGYMVIRRKMPHLFSKRLVGIYLIVLGFLTYIHMYFIIHNLGVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SVVSSTWKLVLENLFRPNQVGFVGGGMIGAAITSVTYFLLDRLGTNLIAALLIIYGFSLV
HHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGISIRQFFSKIAEFVRYLFAKGKVATEKGKEVKAKRDKKKAEKIVEVEPDEVLDVVDPA
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
QEEKAPPIISNFSSKVEQEKAPVEEKTTKQEQDLEMFQQESFENEIYQLPPVDILAPAKV
HHHCCCCHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHCCCEECCCCCEECCCCC
TDQSKEYDQIKVNAKKLEDTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSD
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHCCCC
DIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREVLENNPKNNPDEKLQIALGRD
CCEEEEEEECEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHEEEEECCC
ISGEAMMASLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVELNV
CCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEE
YNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKHNELNEE
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
KQPELPFIVVIVDELADLMMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVI
CCCCCCEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHH
KANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLPVGSSKPTRIQGAFLSDAEVE
HCCCCHHHHHHHHCCCCCCEEECCCCHHHHHCCCCEEEEECCCCCCCEEEECCCCCCHHH
DVVNYVISQQKAQYSEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKFRIG
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YNRAARLIDEMEQRGVVGPHEGSKPRRVNVEINPEHE
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
ATQKKKTSGRKKSSTRSKKKQSASFRLEITGVILIAIGVIGLLQLGFVGRGFFALAEMF
CCCCCCCCCCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH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HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]