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The map label for this gene is comGA

Identifier: 226223948

GI number: 226223948

Start: 1355149

End: 1356171

Strand: Reverse

Name: comGA

Synonym: Lm4b_01355

Alternate gene names: 226223948

Gene position: 1356171-1355149 (Counterclockwise)

Preceding gene: 226223952

Following gene: 226223947

Centisome position: 46.56

GC content: 38.12

Gene sequence:

>1023_bases
ATGCCGCAAAAAATGACAGAACACATCATAACTCAAGCATTACGTGTCCATGCAAGTGATGTTCATATTCATCCACTCTC
AAACCGTTACTTACTCCGTCTTCGGGTAAACGGGACATTGATTCCGCTTCTTTACCTTCCAATAGATGTAGGGGAAAAGT
TAATATCTTTTCTTAAATTCCAAGCAGCTTTGGATATAAGCGAAAAAAGACGACCTCAATCTGGTAGCTTTGAAAAAAAT
ACAAACACAGAAAAAATTGCTATACGGCTTTCTACTATGCCTAGCAAAGATTTTCATGAAAGCATGGTCATTCGAATTTT
TCGTTACAAGTACCCTATCCCATTTTTAAAATCTAGTGTTTTTCCTAGATCCACTAATCAAATTCAACAACAGTGTAAAA
ACCAAACAGGCTTGTTTCTTTTTTCCGGTAGCACAGGTAGTGGTAAGTCCAGTTCTATGTATAGCCTTGTTTCTTCTATA
GAAAATAAAGATGAACTGCAAATCATTACAATTGAAGATCCTGTTGAACATCATTCTCCCGGCTTTCTCCAAATCGAAGT
GAACGAAAAAGCAAGCATTACCTATGCACCCATCATTCGCTCCGTCTTACGCCATGATCCTGATATTTTAATTATCGGGG
AAATACGCGATGCAGAAACCGCTAAAATAGTTGTTCGTGCTGCATTAACCGGTCACTTAGTTTTAAGCACGGTTCATGCC
GGAGATGCTTACGGAGTTTTATTAAGATTACTTGAATTCGGTATTAGCTCAGAAGAATTAGCGCAATGCTTACTAGGAAT
CAGTTTTCAGAAGCTGACACACCTAGTTTGCACCTTCTGCGGAGAAAAATGCCATCCCCTTTGTACACATTTGCACCGAA
AAAGAACAGCTATCTATGAAGTTCTTACGCAACAAGAGATAAAAGCCTATTTCCAATCTAATAAACAGCAGATTAAGCCT
AAATACCCTATTAAAAGAACATTCGAGAAAGGAGTTGCCTATGGTTTTTTTTCAGCGCACTAA

Upstream 100 bases:

>100_bases
TACTTTTGCATTTAGAAAATACTATTTTCGTTTTTGTGAAAGATTGGGACACAAAGGATTTTGTTTACTTTTGAGGAATA
TGACTTGTAAGGAGGTTCTT

Downstream 100 bases:

>100_bases
TTGGAAAGAGGACGGAGAATTTTTAATTAGAGTTGCCAGTTTACTCGAAAAGGGATTCTCATTAGATGCGACCATTAGCT
ATTTAAGCATTACTTCGCCC

Product: comG operon protein 1 (ComGA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPQKMTEHIITQALRVHASDVHIHPLSNRYLLRLRVNGTLIPLLYLPIDVGEKLISFLKFQAALDISEKRRPQSGSFEKN
TNTEKIAIRLSTMPSKDFHESMVIRIFRYKYPIPFLKSSVFPRSTNQIQQQCKNQTGLFLFSGSTGSGKSSSMYSLVSSI
ENKDELQIITIEDPVEHHSPGFLQIEVNEKASITYAPIIRSVLRHDPDILIIGEIRDAETAKIVVRAALTGHLVLSTVHA
GDAYGVLLRLLEFGISSEELAQCLLGISFQKLTHLVCTFCGEKCHPLCTHLHRKRTAIYEVLTQQEIKAYFQSNKQQIKP
KYPIKRTFEKGVAYGFFSAH

Sequences:

>Translated_340_residues
MPQKMTEHIITQALRVHASDVHIHPLSNRYLLRLRVNGTLIPLLYLPIDVGEKLISFLKFQAALDISEKRRPQSGSFEKN
TNTEKIAIRLSTMPSKDFHESMVIRIFRYKYPIPFLKSSVFPRSTNQIQQQCKNQTGLFLFSGSTGSGKSSSMYSLVSSI
ENKDELQIITIEDPVEHHSPGFLQIEVNEKASITYAPIIRSVLRHDPDILIIGEIRDAETAKIVVRAALTGHLVLSTVHA
GDAYGVLLRLLEFGISSEELAQCLLGISFQKLTHLVCTFCGEKCHPLCTHLHRKRTAIYEVLTQQEIKAYFQSNKQQIKP
KYPIKRTFEKGVAYGFFSAH
>Mature_339_residues
PQKMTEHIITQALRVHASDVHIHPLSNRYLLRLRVNGTLIPLLYLPIDVGEKLISFLKFQAALDISEKRRPQSGSFEKNT
NTEKIAIRLSTMPSKDFHESMVIRIFRYKYPIPFLKSSVFPRSTNQIQQQCKNQTGLFLFSGSTGSGKSSSMYSLVSSIE
NKDELQIITIEDPVEHHSPGFLQIEVNEKASITYAPIIRSVLRHDPDILIIGEIRDAETAKIVVRAALTGHLVLSTVHAG
DAYGVLLRLLEFGISSEELAQCLLGISFQKLTHLVCTFCGEKCHPLCTHLHRKRTAIYEVLTQQEIKAYFQSNKQQIKPK
YPIKRTFEKGVAYGFFSAH

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=313, Percent_Identity=34.8242811501597, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1789723, Length=339, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87082188, Length=287, Percent_Identity=27.8745644599303, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 38519; Mature: 38388

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKMTEHIITQALRVHASDVHIHPLSNRYLLRLRVNGTLIPLLYLPIDVGEKLISFLKF
CCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCEEEEEEEEEHHHHHHHHHHHHH
QAALDISEKRRPQSGSFEKNTNTEKIAIRLSTMPSKDFHESMVIRIFRYKYPIPFLKSSV
HHHCCCHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCC
FPRSTNQIQQQCKNQTGLFLFSGSTGSGKSSSMYSLVSSIENKDELQIITIEDPVEHHSP
CCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHCCC
GFLQIEVNEKASITYAPIIRSVLRHDPDILIIGEIRDAETAKIVVRAALTGHLVLSTVHA
CEEEEEECCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEEEECC
GDAYGVLLRLLEFGISSEELAQCLLGISFQKLTHLVCTFCGEKCHPLCTHLHRKRTAIYE
CCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VLTQQEIKAYFQSNKQQIKPKYPIKRTFEKGVAYGFFSAH
HHHHHHHHHHHHCCHHHCCCCCCHHHHHHHCCCCCEECCC
>Mature Secondary Structure 
PQKMTEHIITQALRVHASDVHIHPLSNRYLLRLRVNGTLIPLLYLPIDVGEKLISFLKF
CHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCEEEEEEEEEHHHHHHHHHHHHH
QAALDISEKRRPQSGSFEKNTNTEKIAIRLSTMPSKDFHESMVIRIFRYKYPIPFLKSSV
HHHCCCHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCC
FPRSTNQIQQQCKNQTGLFLFSGSTGSGKSSSMYSLVSSIENKDELQIITIEDPVEHHSP
CCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHCCC
GFLQIEVNEKASITYAPIIRSVLRHDPDILIIGEIRDAETAKIVVRAALTGHLVLSTVHA
CEEEEEECCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEEEECC
GDAYGVLLRLLEFGISSEELAQCLLGISFQKLTHLVCTFCGEKCHPLCTHLHRKRTAIYE
CCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
VLTQQEIKAYFQSNKQQIKPKYPIKRTFEKGVAYGFFSAH
HHHHHHHHHHHHCCHHHCCCCCCHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]