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The map label for this gene is hfq [H]

Identifier: 226223897

GI number: 226223897

Start: 1307998

End: 1308231

Strand: Direct

Name: hfq [H]

Synonym: Lm4b_01304

Alternate gene names: 226223897

Gene position: 1307998-1308231 (Clockwise)

Preceding gene: 226223896

Following gene: 226223898

Centisome position: 44.91

GC content: 35.47

Gene sequence:

>234_bases
ATGAAACAAGGTGGACAAGGGTTACAGGACTATTACTTAAATCAATTGCGTAAGGAAAAAATTCTTGCAACTGTATTTTT
AACAAATGGTTTTCAGTTAAGAGGACGTGTTGTAAGTTTTGACAATTTTACCGTACTACTAGATGTCGAAGGAAAACAAC
AGCTTGTATTTAAACACGCAATTTCAACTTTCTCCCCGCAGAAGAATGTCGCTTTAAATCCTGATGCGGAATAA

Upstream 100 bases:

>100_bases
GAAATAAAGGGTATTTGAAATTAGCCAACCAATTGCACAATGGAACTTCATTGGGGTTTGGGAAATTTTTAGTATAAGAT
AGAGATTGGAGAGGGAAATT

Downstream 100 bases:

>100_bases
GTACTTTACTTGAAAGGCAGGGAACTCGCTTTTTTTGCGATGTTTCATGTCTTTTTTTTATGCAGAAAATATGCTACGAT
TAGTCTTGTCTGAAAAAGGG

Product: host factor-1 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 77; Mature: 77

Protein sequence:

>77_residues
MKQGGQGLQDYYLNQLRKEKILATVFLTNGFQLRGRVVSFDNFTVLLDVEGKQQLVFKHAISTFSPQKNVALNPDAE

Sequences:

>Translated_77_residues
MKQGGQGLQDYYLNQLRKEKILATVFLTNGFQLRGRVVSFDNFTVLLDVEGKQQLVFKHAISTFSPQKNVALNPDAE
>Mature_77_residues
MKQGGQGLQDYYLNQLRKEKILATVFLTNGFQLRGRVVSFDNFTVLLDVEGKQQLVFKHAISTFSPQKNVALNPDAE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=67, Percent_Identity=46.2686567164179, Blast_Score=69, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 8715; Mature: 8715

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQGGQGLQDYYLNQLRKEKILATVFLTNGFQLRGRVVSFDNFTVLLDVEGKQQLVFKHA
CCCCCCCHHHHHHHHHHHHHEEEEEEECCCEEECEEEEECCCEEEEEEECCCHHHHHHHH
ISTFSPQKNVALNPDAE
HHCCCCCCCEEECCCCC
>Mature Secondary Structure
MKQGGQGLQDYYLNQLRKEKILATVFLTNGFQLRGRVVSFDNFTVLLDVEGKQQLVFKHA
CCCCCCCHHHHHHHHHHHHHEEEEEEECCCEEECEEEEECCCEEEEEEECCCHHHHHHHH
ISTFSPQKNVALNPDAE
HHCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]