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The map label for this gene is glpD

Identifier: 226223895

GI number: 226223895

Start: 1305156

End: 1306832

Strand: Direct

Name: glpD

Synonym: Lm4b_01302

Alternate gene names: 226223895

Gene position: 1305156-1306832 (Clockwise)

Preceding gene: 226223894

Following gene: 226223896

Centisome position: 44.81

GC content: 38.04

Gene sequence:

>1677_bases
ATGGTACAATTATTTTCAGCGTTTGACAGAGAAACAATCGAAAGAAATCTTCAAGAGGAAAAATTTGATTTAGTCATCGT
CGGCGGCGGGATTACAGGGGCAGGAATCGCTTTAGATGCCACTTCACGGGGTATGAGTGTCGCACTTGTTGAAATGGGTG
ATTTCGCGAGCGGAACATCGAGCCGTTCAACAAAATTAGTCCACGGTGGATTAAGATATTTACAACAATTTGAAATTAAA
GAAGTAGCAGATTTAGGAAAAGAACGTGCGATAGTCTACGAAAATGGACCACACGTAACGACTCCTGAATGGATGATGCT
CCCATTCCATAAAGGCGGCAATATGGGTAAAACTACCGCTTCATTTGGTATTCGTTTATATGACTATTTAGCAGGGGTAA
AGAAAAATGAACGACGTAAAATTTTAAGCGCAAAAGAAACATTAGCCAAAAATCCATTCGTGAAAAAAGACGGTTTAAAA
GGTTCTGGTTACTACGTGGAATACCGCACGGATGATGCGCGTTTAACAATAGAAGTTATGAAAAAAGCAGTAGAACTCGG
AGCGAATGCTATTAACTATACAAAAGCAGAGCATTTCTTATATGATGACAATAAACAAGTAGTTGGTGTAACCGTAACAG
ATCGTTTGTCGGGCAAAGCATACGATATTAAAGGACATCGTGTTATTAATGCTGCTGGTCCTTGGGTAGATAAAGTAAGA
AAATTAGATTATGCAACAAACAACAAACATTTACGCTTAACAAAAGGAATTCATTTGGTTATTGATAAACAAAAATTCCC
GATGGAACAAGCAGTATACTTTGATACACCTGATGGCCGGATGGTCTTTGCTATTCCGCGCGATAAAAAAGTGTATGTTG
GAACGACGGATACAGTGTACGACGAAGCAGTAATTAATCCAAAAGCACTTGAATCTGATCATAATTATGTGATTAAGGCG
ATTAATTATATGTTCCCTGATGTGCATATTACCGAAAAAGATATTGAATCAAGTTGGGCTGGGGTTCGTCCACTTATCTA
TGAAGAAGGAAAAGATCCATCTGAAATTTCACGTAAAGATGAAGTTTGGTTTTCTGAAAGTGGCTTAATCACGATGGCAG
GTGGTAAACTCACTGGTTACAGAAAAATGGCCGAAAAATTATTAGATGACGTTTCAAAAACATTAGCGAAAGAAACTGGT
AAAAAGTACAAAACAGTTCAAACAAAACATTTACCAATTTCTGGTGGTGACATTGGTGGCTCAGAACAATTAGAAGCTTT
CCTATCTAAAAAAGCGAAAGAAGGTAATAATCGTTTCGGCTGGACTTTAGAAGAAGGTCGTGAGATGGCTAAACGTTTCG
GTAGTAATATCGATCAATTATTTACTTATGCACAGGAACATAAAGAACAAAACGAAACCACTTTACCAAACAGTTTGTAT
GCTGAACTACGCTACTCGATTCAACACGAAGCAGTGACAACGCCAATCGATTTCTTATTACGTCGCACTGGCTACTTGCT
TTTCGATATGCCATACTTACTTGAATGGAAAGACGCTGTTGTGGATGAAATGGCTAAACAATTCCACTGGAGCGACGATG
TAAAACAAACCTATATCGAGGAATTAAATATTCAAATTAATGATGCTAGAGAACCAGCTGATTGGCACGATAGATAA

Upstream 100 bases:

>100_bases
TTTGTTTTTAAACTTAAAGCGTTTCAGTTAGATTGAAAAGTGGAAAAGTAACCAAGAAGGCATAATTCAGACGGTAAACA
ATTTGAAGGGGGCAAACAAA

Downstream 100 bases:

>100_bases
TTAAAATTCGAAAAGAGCGTAAATCTTTCAAGGATTTGCGCTTTTTTTCTGGAAAAAATCATTTTCACTATTTTCAAGAA
ACCTTTTTCATGGTACATTG

Product: glycerol 3 phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATSRGMSVALVEMGDFASGTSSRSTKLVHGGLRYLQQFEIK
EVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTASFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLK
GSGYYVEYRTDDARLTIEVMKKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLSGKAYDIKGHRVINAAGPWVDKVR
KLDYATNNKHLRLTKGIHLVIDKQKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVYDEAVINPKALESDHNYVIKA
INYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKDEVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLAKETG
KKYKTVQTKHLPISGGDIGGSEQLEAFLSKKAKEGNNRFGWTLEEGREMAKRFGSNIDQLFTYAQEHKEQNETTLPNSLY
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVVDEMAKQFHWSDDVKQTYIEELNIQINDAREPADWHDR

Sequences:

>Translated_558_residues
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATSRGMSVALVEMGDFASGTSSRSTKLVHGGLRYLQQFEIK
EVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTASFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLK
GSGYYVEYRTDDARLTIEVMKKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLSGKAYDIKGHRVINAAGPWVDKVR
KLDYATNNKHLRLTKGIHLVIDKQKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVYDEAVINPKALESDHNYVIKA
INYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKDEVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLAKETG
KKYKTVQTKHLPISGGDIGGSEQLEAFLSKKAKEGNNRFGWTLEEGREMAKRFGSNIDQLFTYAQEHKEQNETTLPNSLY
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVVDEMAKQFHWSDDVKQTYIEELNIQINDAREPADWHDR
>Mature_558_residues
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATSRGMSVALVEMGDFASGTSSRSTKLVHGGLRYLQQFEIK
EVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTASFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLK
GSGYYVEYRTDDARLTIEVMKKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLSGKAYDIKGHRVINAAGPWVDKVR
KLDYATNNKHLRLTKGIHLVIDKQKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVYDEAVINPKALESDHNYVIKA
INYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKDEVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLAKETG
KKYKTVQTKHLPISGGDIGGSEQLEAFLSKKAKEGNNRFGWTLEEGREMAKRFGSNIDQLFTYAQEHKEQNETTLPNSLY
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVVDEMAKQFHWSDDVKQTYIEELNIQINDAREPADWHDR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=558, Percent_Identity=33.6917562724014, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI285002231, Length=558, Percent_Identity=33.6917562724014, Blast_Score=258, Evalue=7e-69,
Organism=Escherichia coli, GI2367226, Length=478, Percent_Identity=30.3347280334728, Blast_Score=161, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17509253, Length=556, Percent_Identity=31.4748201438849, Blast_Score=231, Evalue=8e-61,
Organism=Caenorhabditis elegans, GI115534726, Length=557, Percent_Identity=31.5978456014363, Blast_Score=224, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322036, Length=593, Percent_Identity=29.3423271500843, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI161077125, Length=554, Percent_Identity=34.115523465704, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24653942, Length=554, Percent_Identity=34.115523465704, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24653944, Length=554, Percent_Identity=34.115523465704, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI20130025, Length=554, Percent_Identity=34.115523465704, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586295, Length=560, Percent_Identity=25, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI19921278, Length=548, Percent_Identity=25.7299270072993, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 63240; Mature: 63240

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATSRGMSVALVEMGDFASGTS
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCCC
SRSTKLVHGGLRYLQQFEIKEVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHH
SFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLKGSGYYVEYRTDDARLTIEVM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEHHHH
KKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLSGKAYDIKGHRVINAAGPWVDKVR
HHHHHHCCCCCCCCCCHHEEECCCCEEEEEEEEECCCCCEEEECCCEEEECCCCHHHHHH
KLDYATNNKHLRLTKGIHLVIDKQKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVY
HHCCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCEEEEECCCCHH
DEAVINPKALESDHNYVIKAINYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKD
HHHCCCCHHCCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCEEEECCCCHHHHCCCC
EVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLAKETGKKYKTVQTKHLPISGGDIGG
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
SEQLEAFLSKKAKEGNNRFGWTLEEGREMAKRFGSNIDQLFTYAQEHKEQNETTLPNSLY
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHH
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVVDEMAKQFHWSDDVKQTYIE
HHHHHHHHHHHHCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ELNIQINDAREPADWHDR
HCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATSRGMSVALVEMGDFASGTS
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCCC
SRSTKLVHGGLRYLQQFEIKEVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHH
SFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLKGSGYYVEYRTDDARLTIEVM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEHHHH
KKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLSGKAYDIKGHRVINAAGPWVDKVR
HHHHHHCCCCCCCCCCHHEEECCCCEEEEEEEEECCCCCEEEECCCEEEECCCCHHHHHH
KLDYATNNKHLRLTKGIHLVIDKQKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVY
HHCCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCEEEEECCCCHH
DEAVINPKALESDHNYVIKAINYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKD
HHHCCCCHHCCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCEEEECCCCHHHHCCCC
EVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLAKETGKKYKTVQTKHLPISGGDIGG
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCC
SEQLEAFLSKKAKEGNNRFGWTLEEGREMAKRFGSNIDQLFTYAQEHKEQNETTLPNSLY
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHH
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVVDEMAKQFHWSDDVKQTYIE
HHHHHHHHHHHHCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ELNIQINDAREPADWHDR
HCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA