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The map label for this gene is licH [H]

Identifier: 226223165

GI number: 226223165

Start: 577380

End: 578702

Strand: Direct

Name: licH [H]

Synonym: Lm4b_00562

Alternate gene names: 226223165

Gene position: 577380-578702 (Clockwise)

Preceding gene: 226223163

Following gene: 226223166

Centisome position: 19.82

GC content: 40.82

Gene sequence:

>1323_bases
ATGAAAAAAGGTGTAAAAATCGTTACAATTGGTGGGGGTTCCAGTTACACACCAGAACTTGTTGAAGGATTTATTAAACG
CTATCATGAACTTCCAATCAGAGAACTTTGGCTAGTAGATATTGAAGCTGGTCGTGAAAAATTAGAAATCGTTGGTAATA
TGGCAAAACGTATGGTCAAAGCAGCAAACATTGACTGCGAAGTACATTTAACACTTGACCGTCGTGAAGCTCTAAAAGAT
GCAGATTTTGTTACAACACAATTTCGTGTTGGTTTATTAGACGCTCGTATTAAAGATGAAAGAATTCCACTTAGCCACGG
CATCATCGGTCAAGAAACAAACGGAGCGGGCGGAATGTTTAAAGCTTTCCGTACGATTCCTGTCATTCTTGGTATCGTTG
AAGATATGCGCGAACTTTGCCCAGATGCTTGGTTAATCAACTTCACAAACCCAGCAGGTATGGTAACAGAAGCCGTTCTT
CGTTACGGCAACTGGGATAAAGTTATCGGTCTTTGTAACGTGCCAATCGGAGCAGTGAAAAGCGCATCCGACGTTTTAGA
AAAACCAGAAGAAGACTTATTCTTCAAATTTGCTGGAATCAACCACTTGCACTGGCACCGCGTATTCGACAAAGATGGTA
CCGAATTAACAGAAAAAGTTATCGACGGCCTTTATGCACCAGATGCTAACCCAGGAAAAGTCGTTGAAAACATTAAAAAC
ATGCGCTTCTTATATGAGCAAGTTAAACATCTAAAAATGCTTCCTTGTCCATATCACCGTTACTACTACATGACGGATGC
AATGCTTGAAGAAGAACTGGCATCTTTCAAAAACGAAGGTACTCGCGGAGAAGTCGTGAAAAAACTAGAAGACAGCTTAT
TCGAATTATATAAAGACCCAAATCTTGATTACAAACCAGAAGAATTATCCAAACGAGGCGGCGCACATTACAGTGATGCA
GCATGTGAAATCATCAATTCCATTTACAACAACAAAGGTACCGTAATGGTAGTATCTACTCGTAATAACGGCACAATTGA
TGACGTTCCTTACGATAGTGCTGTAGAAATCACAAGTGTTATCCGTGCGCATGGCGCAGAACCAATCAACTTCGGTAAAT
TCCCACCAGCACAACGCGGCTTACTACAAGTAATGAAATCCATGGAAGAATTGACTATCGAAGCAGCAGTAACAGGCGAT
TACGCAACTGCACTACAAGCATTCACTTCTAACCCACTCGTTCCAAGCGGCGACTTAGCAAAAACAATTCTAGATGAAAT
GCTAGAAGCACACAAAGAGTTTTTACCACAATTCGCTAAATAA

Upstream 100 bases:

>100_bases
GATAAATTTAAAATAAGTGCTTGACCTGTAATGCATTACATGAATTATGATGAATGAGAAGAAAAGAAAACGCTTTAAAA
TTCTAGGAGGTAAGTATATT

Downstream 100 bases:

>100_bases
TTCGCAAGTGATCCCTAGAAAATAGGGATCACTTTTTTTGTGAGTTGTTTTAGCGAGCATTTTTTCAAGTTTCCTGTAAA
ATAGAAAAAAGGAGGTGTGC

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKKGVKIVTIGGGSSYTPELVEGFIKRYHELPIRELWLVDIEAGREKLEIVGNMAKRMVKAANIDCEVHLTLDRREALKD
ADFVTTQFRVGLLDARIKDERIPLSHGIIGQETNGAGGMFKAFRTIPVILGIVEDMRELCPDAWLINFTNPAGMVTEAVL
RYGNWDKVIGLCNVPIGAVKSASDVLEKPEEDLFFKFAGINHLHWHRVFDKDGTELTEKVIDGLYAPDANPGKVVENIKN
MRFLYEQVKHLKMLPCPYHRYYYMTDAMLEEELASFKNEGTRGEVVKKLEDSLFELYKDPNLDYKPEELSKRGGAHYSDA
ACEIINSIYNNKGTVMVVSTRNNGTIDDVPYDSAVEITSVIRAHGAEPINFGKFPPAQRGLLQVMKSMEELTIEAAVTGD
YATALQAFTSNPLVPSGDLAKTILDEMLEAHKEFLPQFAK

Sequences:

>Translated_440_residues
MKKGVKIVTIGGGSSYTPELVEGFIKRYHELPIRELWLVDIEAGREKLEIVGNMAKRMVKAANIDCEVHLTLDRREALKD
ADFVTTQFRVGLLDARIKDERIPLSHGIIGQETNGAGGMFKAFRTIPVILGIVEDMRELCPDAWLINFTNPAGMVTEAVL
RYGNWDKVIGLCNVPIGAVKSASDVLEKPEEDLFFKFAGINHLHWHRVFDKDGTELTEKVIDGLYAPDANPGKVVENIKN
MRFLYEQVKHLKMLPCPYHRYYYMTDAMLEEELASFKNEGTRGEVVKKLEDSLFELYKDPNLDYKPEELSKRGGAHYSDA
ACEIINSIYNNKGTVMVVSTRNNGTIDDVPYDSAVEITSVIRAHGAEPINFGKFPPAQRGLLQVMKSMEELTIEAAVTGD
YATALQAFTSNPLVPSGDLAKTILDEMLEAHKEFLPQFAK
>Mature_440_residues
MKKGVKIVTIGGGSSYTPELVEGFIKRYHELPIRELWLVDIEAGREKLEIVGNMAKRMVKAANIDCEVHLTLDRREALKD
ADFVTTQFRVGLLDARIKDERIPLSHGIIGQETNGAGGMFKAFRTIPVILGIVEDMRELCPDAWLINFTNPAGMVTEAVL
RYGNWDKVIGLCNVPIGAVKSASDVLEKPEEDLFFKFAGINHLHWHRVFDKDGTELTEKVIDGLYAPDANPGKVVENIKN
MRFLYEQVKHLKMLPCPYHRYYYMTDAMLEEELASFKNEGTRGEVVKKLEDSLFELYKDPNLDYKPEELSKRGGAHYSDA
ACEIINSIYNNKGTVMVVSTRNNGTIDDVPYDSAVEITSVIRAHGAEPINFGKFPPAQRGLLQVMKSMEELTIEAAVTGD
YATALQAFTSNPLVPSGDLAKTILDEMLEAHKEFLPQFAK

Specific function: Hydrolyzes phospho-beta-glucosides (Probable) [H]

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=445, Percent_Identity=49.8876404494382, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1790560, Length=477, Percent_Identity=26.2054507337526, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 49304; Mature: 49304

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGVKIVTIGGGSSYTPELVEGFIKRYHELPIRELWLVDIEAGREKLEIVGNMAKRMVK
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHEEEEEHHCCHHHHHHHHHHHHHHHH
AANIDCEVHLTLDRREALKDADFVTTQFRVGLLDARIKDERIPLSHGIIGQETNGAGGMF
HHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
KAFRTIPVILGIVEDMRELCPDAWLINFTNPAGMVTEAVLRYGNWDKVIGLCNVPIGAVK
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCHHHEEEEECCCHHHHC
SASDVLEKPEEDLFFKFAGINHLHWHRVFDKDGTELTEKVIDGLYAPDANPGKVVENIKN
CHHHHHHCCCHHHEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
MRFLYEQVKHLKMLPCPYHRYYYMTDAMLEEELASFKNEGTRGEVVKKLEDSLFELYKDP
HHHHHHHHHHHCCCCCCCHHHEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
NLDYKPEELSKRGGAHYSDAACEIINSIYNNKGTVMVVSTRNNGTIDDVPYDSAVEITSV
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
IRAHGAEPINFGKFPPAQRGLLQVMKSMEELTIEAAVTGDYATALQAFTSNPLVPSGDLA
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEHHEECCHHHHHHHHHHCCCCCCCCHHH
KTILDEMLEAHKEFLPQFAK
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKGVKIVTIGGGSSYTPELVEGFIKRYHELPIRELWLVDIEAGREKLEIVGNMAKRMVK
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHEEEEEHHCCHHHHHHHHHHHHHHHH
AANIDCEVHLTLDRREALKDADFVTTQFRVGLLDARIKDERIPLSHGIIGQETNGAGGMF
HHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHH
KAFRTIPVILGIVEDMRELCPDAWLINFTNPAGMVTEAVLRYGNWDKVIGLCNVPIGAVK
HHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCHHHEEEEECCCHHHHC
SASDVLEKPEEDLFFKFAGINHLHWHRVFDKDGTELTEKVIDGLYAPDANPGKVVENIKN
CHHHHHHCCCHHHEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
MRFLYEQVKHLKMLPCPYHRYYYMTDAMLEEELASFKNEGTRGEVVKKLEDSLFELYKDP
HHHHHHHHHHHCCCCCCCHHHEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
NLDYKPEELSKRGGAHYSDAACEIINSIYNNKGTVMVVSTRNNGTIDDVPYDSAVEITSV
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
IRAHGAEPINFGKFPPAQRGLLQVMKSMEELTIEAAVTGDYATALQAFTSNPLVPSGDLA
HHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEHHEECCHHHHHHHHHHCCCCCCCCHHH
KTILDEMLEAHKEFLPQFAK
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 9384377; 8969509 [H]