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The map label for this gene is inlI [H]

Identifier: 226223139

GI number: 226223139

Start: 544225

End: 546054

Strand: Direct

Name: inlI [H]

Synonym: Lm4b_00536

Alternate gene names: 226223139

Gene position: 544225-546054 (Clockwise)

Preceding gene: 226223136

Following gene: 226223140

Centisome position: 18.68

GC content: 37.21

Gene sequence:

>1830_bases
ATGAAAAAAGCACTGAAACTATTTCTTGCGACGATTTGTATGTTCATAATGATATATCCTTCCACAGCAGCTCACGCAGA
AGAAACGAATATTGTTAATATTCCTGATGCAAATCTTAAAACCTATCTTAATGGTCTGCTCAAGCAAGCAAGTGATGCAC
CAATTACTAAAACACAAATGAACACTATCCAAACCGTTACACTTTCTGGCAGCACTTATACAGACTTGACGGGTTTGGAG
GAAGCTGGAAATCTGGTAACACTATCTCTTAACAATACTAACATCCAAACACTTGAACCGATTAAAAACCAAACTTCTTT
GACTTACTTAACAGTGGGCGGAGACAATGTAAAAGATAGTCTTTTCGTAGATTTAAATGGACTTGTTAATTTACAAAGTC
TTAGTATCAGCGGAAGCGAAGTGACACATAATGTCTTTAAGACTTTCAATAAGTTGCCAAAGTTAACTTATCTTTATGCG
CAAAACTCCATGAAAATCACAGATATTTCTGCGCTTGCTTCCTTACCAGCCTTAACGACACTACTCTTACAATTTGATGG
CATTGATGATTTTAGACCTTTAAATGACTTTGAAAGTTTTAAAAATGGCAACTTGAAAGCTCTTGCTGCTTTTGGGCAAA
ATACAGGGCGCACGAATCCAAGAATTACACTTAAATCTGGTAAGTTAGATTATAATGAAACAAACCAAACGTTATATTTA
CCATTTTCGATGATGCCAAAACCTTTAACGAGTTTTGATGGCACTGTTGCACCATTTTCTAAATCGACTTCCGCAAGTAA
TACTTATTTAGGATTTAATGATGTGGCACTCCCAAGCGCACGTCTATCCATTACCGATGATGGTATTACAGTCAGCGGTG
TAACAAAAGAAGAATTCGACAATCTTGATGAAATTGAATATAATGCACGCTATGATTTTCCGACTGGAAGTTACCCGACA
CCACCAAGCATGAATTCTTATACCATCTCCAGCGGGACATATGATCAATATTTTGATATTAGCCACACGCTAGATTTAAC
GGCGGATGAAAGTTTTGACTATAATCAATACGATGCAACATCAGAAGAACAATTTTTAAAAGATGTACATGCTGAAACAG
ATGATGGCACAGCAGTAAAGAGCGATTTTGATCAAGTAGTTAAGCTTGATGTACCGGGTGAATATACCGTGACATTAAAT
GCGGAAAACGCTGCAGGACTAAAAGCAACTCCCGTAACAGTTAAAGTAACCGTTCATGAAAAACCAGTTATTACAGCCGA
TTCCCAAATTTCTTATAAAAAAGAATCAACTAAATCAGTCGACGAATTTTTGCAAGAAATCCATAGTTCGGTAACTGGAA
ATGCAGTTTTAACTAGTGATTTTGATAAAGTAGTAGATTTAAACACCCCAGGCGAATACACCGTAACTTTAAATGCAATA
AATGATCGCGGCCAAAAAGCAGACCCTGTAACCGTAGTTGTGACAGTGACTACTAGCGACGGCGGACATGTTAATCCGGT
TCCACCAACTCCAGAAGTAAAACCCACACCTCAAGAAGAAACCGACCCAACAATCATCCCAGAACCTCAAAGCGAAAATT
CAGAAGACCCAGTGAAAGAAAATAATGCAAAAACAGAAGAAAAAGCAAATAAAACTTCTTTAACAACGAAAGAAAACAAA
GTAGAAAAAGCAGATAAAGCAGAAAAAACAAATCAACCGAAAACAAAAGCTTTGCCACAAACTGGTGATACTAATAAGAG
CACCTTACCAATCGCAGGAGTAATGCTGAGTTTAGCGGCACTGCTGATTTTCAGAAAAAGCAAATCTTAA

Upstream 100 bases:

>100_bases
TAAGGCAAATCAAACGTGAAATATTTTATGAAAACGTATTGAGAGTTAGTTTTAACGCGGTTATACTTTGGGAAGAAATT
AACCACTAAGGAGAGTATAA

Downstream 100 bases:

>100_bases
GTTATTGTGAATTCATTAGCAAAAAGAATGAATGGCAGGCCTAAAATCATTTTTATAGGGTATGGAATACTATAAGAAAA
GTTGTAGGAGGTTTTATATG

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLE
EAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSISGSEVTHNVFKTFNKLPKLTYLYA
QNSMKITDISALASLPALTTLLLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYL
PFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITDDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPT
PPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLN
AENAAGLKATPVTVKVTVHEKPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAI
NDRGQKADPVTVVVTVTTSDGGHVNPVPPTPEVKPTPQEETDPTIIPEPQSENSEDPVKENNAKTEEKANKTSLTTKENK
VEKADKAEKTNQPKTKALPQTGDTNKSTLPIAGVMLSLAALLIFRKSKS

Sequences:

>Translated_609_residues
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLE
EAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSISGSEVTHNVFKTFNKLPKLTYLYA
QNSMKITDISALASLPALTTLLLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYL
PFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITDDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPT
PPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLN
AENAAGLKATPVTVKVTVHEKPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAI
NDRGQKADPVTVVVTVTTSDGGHVNPVPPTPEVKPTPQEETDPTIIPEPQSENSEDPVKENNAKTEEKANKTSLTTKENK
VEKADKAEKTNQPKTKALPQTGDTNKSTLPIAGVMLSLAALLIFRKSKS
>Mature_609_residues
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLE
EAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSISGSEVTHNVFKTFNKLPKLTYLYA
QNSMKITDISALASLPALTTLLLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYL
PFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITDDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPT
PPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDATSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLN
AENAAGLKATPVTVKVTVHEKPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAI
NDRGQKADPVTVVVTVTTSDGGHVNPVPPTPEVKPTPQEETDPTIIPEPQSENSEDPVKENNAKTEEKANKTSLTTKENK
VEKADKAEKTNQPKTKALPQTGDTNKSTLPIAGVMLSLAALLIFRKSKS

Specific function: Unknown. A role in virulence could not be demonstrated [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 MucBP domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR000601
- InterPro:   IPR001899 [H]

Pfam domain/function: PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 66350; Mature: 66350

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQM
CHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEEEC
NTIQTVTLSGSTYTDLTGLEEAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDS
CEEEEEEECCCCCCCCCCHHHCCCEEEEEECCCCCEEECCCCCCCEEEEEEECCCCCCCE
LFVDLNGLVNLQSLSISGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTT
EEEEECCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHHHHH
LLLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYL
HHHHCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEE
PFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITDDGITVSGVTKEEFD
EHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEECCCHHHHC
NLDEIEYNARYDFPTGSYPTPPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDAT
CCCCEEECEEECCCCCCCCCCCCCCCEEECCCCCCCEEECEEEEEECCCCCCCCCCCCCC
SEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHE
CHHHHHHHHCCCCCCCCEECCCCCCEEEEECCCEEEEEEECCCCCCCEECCEEEEEEEEC
KPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAI
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHEEECCCCCCEEEEEEEE
NDRGQKADPVTVVVTVTTSDGGHVNPVPPTPEVKPTPQEETDPTIIPEPQSENSEDPVKE
CCCCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
NNAKTEEKANKTSLTTKENKVEKADKAEKTNQPKTKALPQTGDTNKSTLPIAGVMLSLAA
CCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHH
LLIFRKSKS
HHHHHCCCC
>Mature Secondary Structure
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQM
CHHHHHHHHHHHHHHHEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCEEEEC
NTIQTVTLSGSTYTDLTGLEEAGNLVTLSLNNTNIQTLEPIKNQTSLTYLTVGGDNVKDS
CEEEEEEECCCCCCCCCCHHHCCCEEEEEECCCCCEEECCCCCCCEEEEEEECCCCCCCE
LFVDLNGLVNLQSLSISGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTT
EEEEECCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHHHHH
LLLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYL
HHHHCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCEEEE
PFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSARLSITDDGITVSGVTKEEFD
EHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEECCCHHHHC
NLDEIEYNARYDFPTGSYPTPPSMNSYTISSGTYDQYFDISHTLDLTADESFDYNQYDAT
CCCCEEECEEECCCCCCCCCCCCCCCEEECCCCCCCEEECEEEEEECCCCCCCCCCCCCC
SEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHE
CHHHHHHHHCCCCCCCCEECCCCCCEEEEECCCEEEEEEECCCCCCCEECCEEEEEEEEC
KPVITADSQISYKKESTKSVDEFLQEIHSSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAI
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHEEECCCCCCEEEEEEEE
NDRGQKADPVTVVVTVTTSDGGHVNPVPPTPEVKPTPQEETDPTIIPEPQSENSEDPVKE
CCCCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCC
NNAKTEEKANKTSLTTKENKVEKADKAEKTNQPKTKALPQTGDTNKSTLPIAGVMLSLAA
CCCCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHH
LLIFRKSKS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]