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The map label for this gene is sigH

Identifier: 226222872

GI number: 226222872

Start: 259263

End: 259868

Strand: Direct

Name: sigH

Synonym: Lm4b_00263

Alternate gene names: 226222872

Gene position: 259263-259868 (Clockwise)

Preceding gene: 226222871

Following gene: 226222873

Centisome position: 8.9

GC content: 37.46

Gene sequence:

>606_bases
GTGGATAATTCAGTGAACCAAGAAGAACTTGCGATGCTTGAACTAGCGAGAAGCGGTGATACAGAAGCGTTAGAATATTT
TTTCAGTAAGTATCAGTCTGTTATTTACTGGAAATCAACCCAATATTTTCTGCAAGGTGCGGAGCGGGACGATTTAATTC
AAGAAGCGATGATTGGCCTTTTCAAAGCAATTCGGGATTACGATAAAACAAAAGAAGCTTCTTTTCGATCTTTTGCAGAA
ATGTGTATTAACAGACAGCTTCTTTCGGCGGTGAAGCGGGCGTCTAGACAGAAGAATATTCCGCTTAATAATTCTGTTTC
ATTAGATACACCAATAGCTGAGGATGATATGGACTGGACTTTATTAGACGTGATTTCCGAAAAAGCAGCCGAAACCCCAG
AAGACTTTTTAATCAAAAACGAAGATTTAACGCATGTAGCGCGTCAACTAGAACAAGTCACAAGCGAATTTGAAAAAGAA
GTATTAAAACAATATTTAGAAGGTAAGAGCTATCAAGAAATGGCGCTTTTCTTCAACAAAAAAGAGAAAGCAATCGATAA
TGCCTTACAACGTGTAAAAAAGAAAATGATGAAACAGCTAGAATGA

Upstream 100 bases:

>100_bases
GGAGAAGAGGCGAGGAGTAAGGGATTGACGGTATGTTTTTGACTATGTATAATGGAGCAACCATAGAAGAAATCCTGTCG
TAAAGGAGCCGATTAGCCTA

Downstream 100 bases:

>100_bases
AAAAACAATTGACTAGCTAAGAGCCAGATGTTATATTTATATGGATGAAATGTGCCTATTTTTTGGCATGGCATATTTAA
TGATTGCGGAGTTGAGATAA

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MDNSVNQEELAMLELARSGDTEALEYFFSKYQSVIYWKSTQYFLQGAERDDLIQEAMIGLFKAIRDYDKTKEASFRSFAE
MCINRQLLSAVKRASRQKNIPLNNSVSLDTPIAEDDMDWTLLDVISEKAAETPEDFLIKNEDLTHVARQLEQVTSEFEKE
VLKQYLEGKSYQEMALFFNKKEKAIDNALQRVKKKMMKQLE

Sequences:

>Translated_201_residues
MDNSVNQEELAMLELARSGDTEALEYFFSKYQSVIYWKSTQYFLQGAERDDLIQEAMIGLFKAIRDYDKTKEASFRSFAE
MCINRQLLSAVKRASRQKNIPLNNSVSLDTPIAEDDMDWTLLDVISEKAAETPEDFLIKNEDLTHVARQLEQVTSEFEKE
VLKQYLEGKSYQEMALFFNKKEKAIDNALQRVKKKMMKQLE
>Mature_201_residues
MDNSVNQEELAMLELARSGDTEALEYFFSKYQSVIYWKSTQYFLQGAERDDLIQEAMIGLFKAIRDYDKTKEASFRSFAE
MCINRQLLSAVKRASRQKNIPLNNSVSLDTPIAEDDMDWTLLDVISEKAAETPEDFLIKNEDLTHVARQLEQVTSEFEKE
VLKQYLEGKSYQEMALFFNKKEKAIDNALQRVKKKMMKQLE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23436; Mature: 23436

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNSVNQEELAMLELARSGDTEALEYFFSKYQSVIYWKSTQYFLQGAERDDLIQEAMIGL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHH
FKAIRDYDKTKEASFRSFAEMCINRQLLSAVKRASRQKNIPLNNSVSLDTPIAEDDMDWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
LLDVISEKAAETPEDFLIKNEDLTHVARQLEQVTSEFEKEVLKQYLEGKSYQEMALFFNK
HHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KEKAIDNALQRVKKKMMKQLE
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNSVNQEELAMLELARSGDTEALEYFFSKYQSVIYWKSTQYFLQGAERDDLIQEAMIGL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHH
FKAIRDYDKTKEASFRSFAEMCINRQLLSAVKRASRQKNIPLNNSVSLDTPIAEDDMDWT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
LLDVISEKAAETPEDFLIKNEDLTHVARQLEQVTSEFEKEVLKQYLEGKSYQEMALFFNK
HHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KEKAIDNALQRVKKKMMKQLE
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]