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The map label for this gene is ctsR [H]

Identifier: 226222858

GI number: 226222858

Start: 245160

End: 245618

Strand: Direct

Name: ctsR [H]

Synonym: Lm4b_00249

Alternate gene names: 226222858

Gene position: 245160-245618 (Clockwise)

Preceding gene: 226222857

Following gene: 226222859

Centisome position: 8.42

GC content: 31.37

Gene sequence:

>459_bases
ATGAAAAACATTTCTGATGTTATAGAAGCTTATTTGAAACAAGTATTGGAATCAAGTGAAGCAGTGGAAATTAAAAGAAG
TGAAATTGCAGATAAGTTTGAATGTGTACCTTCACAAATTAATTATGTAATAAACACTAGATTTACAATGGAACGAGGGT
ATATCGTTGAAAGTAAACGTGGTGGTGGTGGCTATATTAGGATTATTAAAGTGAAAATGAATGATAAACTTCAATTGTTA
GAAGCAATCATTTCAATGGTTCATGATAAAAAGGTCTCTCAATCATTTTCTGAAGATGTTATTTTGAGATTGCTTGAAGA
AGAAGTAATAACGAAGAAAGAAGCAAGATTAATGGTGGCGGCATTGGACAGGGAAGTTTTAATTTTACCATTACCCGATA
GAGATATTTTGAGAAGTAGGATTTTAGAGGCGATGTTAGTTGCTTTGAAATATGATTAA

Upstream 100 bases:

>100_bases
AGATAAATAAATTGCTAATAGGTAGGGATATCTAGTATAATTAAAGTCAAAAATAGTCAAAGTCAATGATTTGCAAAAAA
CAGAAAGGAGATTCCTTATA

Downstream 100 bases:

>100_bases
GGTGTGATGACGATGATTTGTCAAAGATGTGGAGAAAATAAAGCAGTTATTGCCTTGCAACAATTAAATGAGCTTGGGAA
AGTGGAGTCATTGTACCTAT

Product: transcription repressor of class III stress genes (CtsR)

Products: NA

Alternate protein names: Class three stress gene repressor [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKNISDVIEAYLKQVLESSEAVEIKRSEIADKFECVPSQINYVINTRFTMERGYIVESKRGGGGYIRIIKVKMNDKLQLL
EAIISMVHDKKVSQSFSEDVILRLLEEEVITKKEARLMVAALDREVLILPLPDRDILRSRILEAMLVALKYD

Sequences:

>Translated_152_residues
MKNISDVIEAYLKQVLESSEAVEIKRSEIADKFECVPSQINYVINTRFTMERGYIVESKRGGGGYIRIIKVKMNDKLQLL
EAIISMVHDKKVSQSFSEDVILRLLEEEVITKKEARLMVAALDREVLILPLPDRDILRSRILEAMLVALKYD
>Mature_152_residues
MKNISDVIEAYLKQVLESSEAVEIKRSEIADKFECVPSQINYVINTRFTMERGYIVESKRGGGGYIRIIKVKMNDKLQLL
EAIISMVHDKKVSQSFSEDVILRLLEEEVITKKEARLMVAALDREVLILPLPDRDILRSRILEAMLVALKYD

Specific function: Controls the expression of the cellular protein quality control genes clpC, clpE and clpP. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock,

COG id: COG4463

COG function: function code K; Transcriptional repressor of class III stress genes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CtsR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008463 [H]

Pfam domain/function: PF05848 CtsR [H]

EC number: NA

Molecular weight: Translated: 17471; Mature: 17471

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNISDVIEAYLKQVLESSEAVEIKRSEIADKFECVPSQINYVINTRFTMERGYIVESKR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCEEEECEEEEECCEEEECCC
GGGGYIRIIKVKMNDKLQLLEAIISMVHDKKVSQSFSEDVILRLLEEEVITKKEARLMVA
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ALDREVLILPLPDRDILRSRILEAMLVALKYD
ECCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNISDVIEAYLKQVLESSEAVEIKRSEIADKFECVPSQINYVINTRFTMERGYIVESKR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCEEEECEEEEECCEEEECCC
GGGGYIRIIKVKMNDKLQLLEAIISMVHDKKVSQSFSEDVILRLLEEEVITKKEARLMVA
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
ALDREVLILPLPDRDILRSRILEAMLVALKYD
ECCCCEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]