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The map label for this gene is yabR [H]

Identifier: 226222847

GI number: 226222847

Start: 220616

End: 221044

Strand: Direct

Name: yabR [H]

Synonym: Lm4b_00216

Alternate gene names: 226222847

Gene position: 220616-221044 (Clockwise)

Preceding gene: 226222846

Following gene: 226222848

Centisome position: 7.57

GC content: 41.03

Gene sequence:

>429_bases
ATGTCGATCGAAGTAGGCAACAAGTTACAAGGGAAAGTTACTGGGATTACTAATTTTGGAGCATTTGTGGAGCTGGAAGG
TGGCAAAACAGGTTTAGTCCATATTAGTGAGGTAGCAGATAACTATGTTAAAGACATTAATGACATCTTAACTGTAGGGG
ATGAAGTTACTGTTAAAGTAATGAATATTGGTGATGATGGTAAGATTGGTCTGTCCATTCGTAAAGCAGTAGATCGTCCG
GACCGCCCAGAGAAAAGTTACGATCGTAAGCCGAAATACAGCAAAAAACCTGCTGGGAACTATGTGAAACCAGCCGAGAG
CTTTGAAGATATAATGTCTAAATTCTTGAAAGATAGTGATGAAAGACTCACTACTATCAAACGCCAAACAGAATCTAAAC
GTGGCGGCCGAGGAGCAAAACGCGGCTAA

Upstream 100 bases:

>100_bases
TGAGTATTTTTGGGGTTTGTAAGTTTGACTGTTTGACACTCTTTTTATTATAGCTATAATTAAGCAATAGAGTGATATTT
TAAGGAGGACGCATTTTTTT

Downstream 100 bases:

>100_bases
TACGCTAAAATTAATTGTAAAGTAGATGCACCGTATTGGATCATTAATACGGTGCACTTTTTAATAAAAAATGTGAGAGC
CGAATTTCGAAGGAAGGTTT

Product: hypothetical protein

Products: RNAn; a nucleoside diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSIEVGNKLQGKVTGITNFGAFVELEGGKTGLVHISEVADNYVKDINDILTVGDEVTVKVMNIGDDGKIGLSIRKAVDRP
DRPEKSYDRKPKYSKKPAGNYVKPAESFEDIMSKFLKDSDERLTTIKRQTESKRGGRGAKRG

Sequences:

>Translated_142_residues
MSIEVGNKLQGKVTGITNFGAFVELEGGKTGLVHISEVADNYVKDINDILTVGDEVTVKVMNIGDDGKIGLSIRKAVDRP
DRPEKSYDRKPKYSKKPAGNYVKPAESFEDIMSKFLKDSDERLTTIKRQTESKRGGRGAKRG
>Mature_141_residues
SIEVGNKLQGKVTGITNFGAFVELEGGKTGLVHISEVADNYVKDINDILTVGDEVTVKVMNIGDDGKIGLSIRKAVDRPD
RPEKSYDRKPKYSKKPAGNYVKPAESFEDIMSKFLKDSDERLTTIKRQTESKRGGRGAKRG

Specific function: Involved In Mrna Degradation. Hydrolyzes Single-Stranded Polyribonucleotides Processively In The 3' To 5' Direction. Involved In The RNA Degradosome, A Multi-Enzyme Complex Important In RNA Processing And Messenger RNA Degradation. [C]

COG id: COG1098

COG function: function code J; Predicted RNA binding protein (contains ribosomal protein S1 domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI145693187, Length=77, Percent_Identity=51.9480519480519, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1000 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 3328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967 [H]

Pfam domain/function: PF00575 S1 [H]

EC number: 2.7.7.8 [C]

Molecular weight: Translated: 15647; Mature: 15516

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEVGNKLQGKVTGITNFGAFVELEGGKTGLVHISEVADNYVKDINDILTVGDEVTVKV
CCCCCCCCCCCEEEEEECCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEE
MNIGDDGKIGLSIRKAVDRPDRPEKSYDRKPKYSKKPAGNYVKPAESFEDIMSKFLKDSD
EEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCH
ERLTTIKRQTESKRGGRGAKRG
HHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SIEVGNKLQGKVTGITNFGAFVELEGGKTGLVHISEVADNYVKDINDILTVGDEVTVKV
CCCCCCCCCCEEEEEECCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEE
MNIGDDGKIGLSIRKAVDRPDRPEKSYDRKPKYSKKPAGNYVKPAESFEDIMSKFLKDSD
EEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCH
ERLTTIKRQTESKRGGRGAKRG
HHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): 4500 [C]

Specific activity: NA

Km value (mM): NA

Substrates: RNAn+1; phosphate [C]

Specific reaction: RNAn+1 + phosphate = RNAn + a nucleoside diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8113187; 7584024; 9384377 [H]