Click here to switch to the map view.

The map label for this gene is pabA [H]

Identifier: 225861618

GI number: 225861618

Start: 1652401

End: 1652967

Strand: Reverse

Name: pabA [H]

Synonym: SPT_1739

Alternate gene names: 225861618

Gene position: 1652967-1652401 (Counterclockwise)

Preceding gene: 225861619

Following gene: 225861617

Centisome position: 78.26

GC content: 42.68

Gene sequence:

>567_bases
ATGATTTTATTGATTGACAACTATGATTCTTTTACCTATAACTTGGCCCAATACATTGGGAATTTTGCAGAAGTTCAGGT
TCTGAGAAATGATGATTCCAAGCTGTATGAAGAAGCTGAAAAAGCAGATGGTCTGGTCTTTTCTCCTGGTCCTGGTTGGC
CAGTTGATGCTGGAAAGATGGAAGACATGATTTGTGATTTTGCAGGCAAGAAGCCGATTCTAGGGATTTGTTTGGGTCAC
CAAGCCATTGCAGAAGTCTTTGGTGGTAAGCTAGGTTTGGCTCCAAAAGTCATGCATGGGAAACAGAGCAATATCAACTT
TGAAGCGCCATCTGTTTTGTATCAAGGTATTGAGGATGGCCGTGCGGTCATGCGTTATCACAGTATTTTGATTGAGGAAA
TGCCAGAAGACTTTGAAGTGACAGCTCGTTCGACTGATGACCAAGCCATCATGGGGATTCAACATAAAAACCTACCAATT
TATGGCTTCCAGTACCATCCAGAGAGCATTGGAACGCCAGACGGCTTGTCTTCTATTCGGAATTTTATCGAGGAGGTTGT
AAAGTGA

Upstream 100 bases:

>100_bases
AGGCTGGGGCAGGGATTGTCTACGACTCTATCGCCCAAAACGAATACCAAGAAACCATTAACAAAGCAAAATCTATGACT
AGAATTGGAGAACTAAGACC

Downstream 100 bases:

>100_bases
GGAAACTAGGATGAAAGAGATTATTGAAAAACTAGCAAAATTTGAAAATTTATCAGGTGTGGAAATGACGGATGTCATTG
AGCGTATCGTAACTGGGCGT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADGLVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGH
QAIAEVFGGKLGLAPKVMHGKQSNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
YGFQYHPESIGTPDGLSSIRNFIEEVVK

Sequences:

>Translated_188_residues
MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADGLVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGH
QAIAEVFGGKLGLAPKVMHGKQSNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
YGFQYHPESIGTPDGLSSIRNFIEEVVK
>Mature_188_residues
MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADGLVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGH
QAIAEVFGGKLGLAPKVMHGKQSNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
YGFQYHPESIGTPDGLSSIRNFIEEVVK

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=120, Percent_Identity=30.8333333333333, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=47.6190476190476, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1787517, Length=179, Percent_Identity=40.7821229050279, Blast_Score=127, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=43.3155080213904, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323873, Length=183, Percent_Identity=27.3224043715847, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281365319, Length=169, Percent_Identity=29.585798816568, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 20874; Mature: 20874

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADGLVFSPGPGWPVDAGKM
CEEEEECCCCHHHHHHHHHCCHHEEEEEECCCHHHHHHHHHCCCEEECCCCCCCCCCCHH
EDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQSNINFEAPSVLYQGIEDG
HHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHCHHHH
RAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPIYGFQYHPESIGTPDGLSSIR
HHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHH
NFIEEVVK
HHHHHHHC
>Mature Secondary Structure
MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADGLVFSPGPGWPVDAGKM
CEEEEECCCCHHHHHHHHHCCHHEEEEEECCCHHHHHHHHHCCCEEECCCCCCCCCCCHH
EDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQSNINFEAPSVLYQGIEDG
HHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHCHHHH
RAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPIYGFQYHPESIGTPDGLSSIR
HHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHH
NFIEEVVK
HHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]