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The map label for this gene is dtd [H]

Identifier: 225861473

GI number: 225861473

Start: 1501609

End: 1502052

Strand: Reverse

Name: dtd [H]

Synonym: SPT_1584

Alternate gene names: 225861473

Gene position: 1502052-1501609 (Counterclockwise)

Preceding gene: 225861474

Following gene: 225861470

Centisome position: 71.11

GC content: 41.22

Gene sequence:

>444_bases
ATGAAAATCATTATCCAACGGGTTAAAAAAGCCCAAGTGAGTATAGAAGGCCAGATTCAGGGAAAAATCAATCAGGGACT
TTTATTGCTGGTTGGTGTTGGACCAGAGGACCAAGAGGAAGATTTGGACTATGCTGTGAGAAAACTGGTCAATATGCGGA
TTTTTTCAGACGTAGAAGGCAAGATGAACCTGTCTGTCAAAGATATTGAAGGAGAAATCCTCTCTATTTCTCAGTTTACC
CTCTTTGCGGATACTAAGAAAGGCAATCGTCCAGCCTTTACAGGGGCAGCTAAACCTGATATGGCATCAGACTTCTATGA
TGCTTTCAATCAAAAATTAGCGCAAGAAGTGCCCGTTCAGACAGGTATCTTTGGAGCAGATATGCAGGTTGAGCTGGTTA
ATAACGGACCTGTTACCATTATCCTAGATACTAAAAAGAGATAA

Upstream 100 bases:

>100_bases
CACTGACCACGGTTGTCGATAAAATTAAGAGTGTGCCAGAAGTTTACTCTGTCAAACGGACCAACGGCTAGTTGTCCTAG
CTCTTACTAGAAAGGCTATT

Downstream 100 bases:

>100_bases
GAAAGACCAAGCCCAGTCGGCTTGGTCTTTCTCATCGATCATAAAATACTCCAAAAAGAAATCGGTTCTTGATATGCTTG
GGGGAAGTCTCTTTTCAGGC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDVEGKMNLSVKDIEGEILSISQFT
LFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR

Sequences:

>Translated_147_residues
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDVEGKMNLSVKDIEGEILSISQFT
LFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR
>Mature_147_residues
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDVEGKMNLSVKDIEGEILSISQFT
LFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=40.5405405405405, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=49.6503496503497, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115533292, Length=151, Percent_Identity=41.7218543046358, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.2162162162162, Blast_Score=112, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=40.1360544217687, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16242; Mature: 16242

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDVEG
CHHHHHHHHHHHEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCC
KMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQ
EEEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TGIFGADMQVELVNNGPVTIILDTKKR
CCEECCCEEEEEECCCCEEEEEECCCC
>Mature Secondary Structure
MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDYAVRKLVNMRIFSDVEG
CHHHHHHHHHHHEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCC
KMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMASDFYDAFNQKLAQEVPVQ
EEEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
TGIFGADMQVELVNNGPVTIILDTKKR
CCEECCCEEEEEECCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA