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The map label for this gene is macB [H]

Identifier: 225861310

GI number: 225861310

Start: 1346703

End: 1347962

Strand: Reverse

Name: macB [H]

Synonym: SPT_1413

Alternate gene names: 225861310

Gene position: 1347962-1346703 (Counterclockwise)

Preceding gene: 225861311

Following gene: 225861309

Centisome position: 63.82

GC content: 39.84

Gene sequence:

>1260_bases
ATGCAGAATCTGAAATTTGCCTTTTCATCTATCATGGCTCACAAGATGCGTTCTTTGCTTACTATGATTGGGATTATTAT
CGGTGTTTCATCAGTTGTTGTGATTATGGCTTTGGGTGATTCCCTATCTCGTCAAGTCAATAAAGATATGACTAAATCTC
AGAAAAATATTAGCGTCTTTTTCTCTCCTAAAAAAAGTAAAGATGGGTCTTTTACTCAGAAACAATCAGCTTTTACGGTT
TCTGGAAAGGAAGAGGAAGTTCCTGTTGAACCGCCAAAACCGCAAGAATCCTGGGTTCAAGAGGCAGCTAAACTGAAGGG
AGTGGATAGTTACTATGTAACCAATTCAACGAATGCCATCTTGACCTATCAAGATAAAAAGGTTGAGAATGCTAATTTGA
CAGGTGGAAACAGAACTTACATGGACGCTGTTAAGAATGAAATTATTGCAGGTCGTAGTCTGAGAGAGCAAGATTTCAAA
GAGTTTGCAAGTGTCATTTTGCTAGATGAGGAATTGTCCATTAGTTTATTTGAATCTCCTCAAGAGGCTATTAACAAGGT
TGTAGAAGTCAATGGATTTAGTTACCGGGTCATTGGGGTTTATACTAGTCCGGAGGCTAAAAGATCAAAAATATATGGGT
TTGGTGGCTTGCCTATTACTACCAATATCTCCCTTGCTGCGAATTTTAATGTAGATGAAATAGCTAATATTGTCTTTCGA
GTGAATGATACCAGTTTAACCCCAACTCTGGGTCCAGAATTGGCACGAAAAATGACAGAGCTTGCAGGCTTACAACAGGG
AGAATACCAGGTGGCAGATGAGTCCGTTGTATTTGCAGAAATTCAACAATCGTTTAGTTTTATGACGACGATTATTAGTT
CCATCGCAGGGATTTCTCTCTTTGTTGGAGGAACTGGTGTCATGAACATCATGCTGGTTTCGGTGACAGAGCGCACTCGT
GAGATTGGTCTTCGTAAGGCTTTGGGCGCAACACGTGCCAATATTTTAATTCAGTTTTTGATTGAATCCATGATTTTGAC
CTTGTTAGGTGGCTTAATTGGCTTGACAATTGCAAGTGGTTTAACTGCCTTAGCAGGTTTGTTACTGCAAGGTTTAATAG
AAGGTATAGAAGTTGGAGTATCAATCCCAGTTGCCCTATTTAGTCTTGCAGTTTCGGCTAGTGTTGGTATGATTTTTGGA
GTCTTGCCAGCCAACAAGGCATCGAAACTTGATCCAATTGAAGCCCTTCGTTATGAATGA

Upstream 100 bases:

>100_bases
CATGAGCCTGAGATTGCTGCCTATGCCAAACGTCAGATTGTCATTCGGGATGGGGTCATTTCGTCTGACAGTGCTCAGTT
AGGAAAGGAGGAAAACTAAG

Downstream 100 bases:

>100_bases
GATCAACAAGATGGACACTCGTCTATCTTGTTTTTGTATGGATTTCCCTATCGAAATTCATTAAAAATGTGATATAATGA
AGTGTTAGAAAAACAGGTTT

Product: ABC-type antimicrobial peptide transport system, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSRQVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTV
SGKEEEVPVEPPKPQESWVQEAAKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLPITTNISLAANFNVDEIANIVFR
VNDTSLTPTLGPELARKMTELAGLQQGEYQVADESVVFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTR
EIGLRKALGATRANILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVSASVGMIFG
VLPANKASKLDPIEALRYE

Sequences:

>Translated_419_residues
MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSRQVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTV
SGKEEEVPVEPPKPQESWVQEAAKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLPITTNISLAANFNVDEIANIVFR
VNDTSLTPTLGPELARKMTELAGLQQGEYQVADESVVFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTR
EIGLRKALGATRANILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVSASVGMIFG
VLPANKASKLDPIEALRYE
>Mature_419_residues
MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSRQVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTV
SGKEEEVPVEPPKPQESWVQEAAKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLPITTNISLAANFNVDEIANIVFR
VNDTSLTPTLGPELARKMTELAGLQQGEYQVADESVVFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTR
EIGLRKALGATRANILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVSASVGMIFG
VLPANKASKLDPIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=426, Percent_Identity=32.3943661971831, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45291; Mature: 45291

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSRQVNKDMTKSQKNISVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEE
FSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEAAKLKGVDSYYVTNSTNAI
ECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
LTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFKEFASVILLDEELSISLFESP
EEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCHHHHCCH
QEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLPITTNISLAANFNVDEIANIVFR
HHHHHHHHCCCCCEEEEEEEEECCCHHHCEEEECCCCCEEEEEEEEECCCHHHHHHHHEE
VNDTSLTPTLGPELARKMTELAGLQQGEYQVADESVVFAEIQQSFSFMTTIISSIAGISL
ECCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEE
FVGGTGVMNIMLVSVTERTREIGLRKALGATRANILIQFLIESMILTLLGGLIGLTIASG
EECCCCEEHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALAGLLLQGLIEGIEVGVSIPVALFSLAVSASVGMIFGVLPANKASKLDPIEALRYE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSRQVNKDMTKSQKNISVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEE
FSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEAAKLKGVDSYYVTNSTNAI
ECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEE
LTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFKEFASVILLDEELSISLFESP
EEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCHHHHCCH
QEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLPITTNISLAANFNVDEIANIVFR
HHHHHHHHCCCCCEEEEEEEEECCCHHHCEEEECCCCCEEEEEEEEECCCHHHHHHHHEE
VNDTSLTPTLGPELARKMTELAGLQQGEYQVADESVVFAEIQQSFSFMTTIISSIAGISL
ECCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHEE
FVGGTGVMNIMLVSVTERTREIGLRKALGATRANILIQFLIESMILTLLGGLIGLTIASG
EECCCCEEHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTALAGLLLQGLIEGIEVGVSIPVALFSLAVSASVGMIFGVLPANKASKLDPIEALRYE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA