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The map label for this gene is ywcF [H]

Identifier: 225861293

GI number: 225861293

Start: 1328969

End: 1330192

Strand: Reverse

Name: ywcF [H]

Synonym: SPT_1396

Alternate gene names: 225861293

Gene position: 1330192-1328969 (Counterclockwise)

Preceding gene: 225861294

Following gene: 225861292

Centisome position: 62.98

GC content: 40.28

Gene sequence:

>1224_bases
ATGAAACGTTCTCTCGACTCTAGAGTCGATTATAGTTTGCTCTTGCCAGTATTTTTTCTACTGGTCATCGGTGTGGTGGC
TATCTATATAGCCGTTAGTCATGATTATCCCAATAATATTCTGCCCATTTTAGGGCAGCAGGTCGCCTGGATTGCCTTGG
GGCTTGTGATTGGTTTTGTGGTCATGCTCTTTAATACAGAATTTCTTTGGAAGGTGACCCCCTTTCTATATATTTTAGGC
TTGGGACTTATGATCTTGCCGATTGTATTTTATAATCCAAGCTTAGTTGCATCAACGGGTGCCAAAAACTGGGTATCAAT
AAATGGAATTACCCTATTTCAACCGTCAGAATTTATGAAGATATCCTATATCCTCATGTTGGCTCGTGTCATTGTCCAAT
TTACAAAGAAACATAAGGAATGGAGACGCACGGTTCCGCTGGACTTTTTGTTAATTTTCTGGATGATTCTCTTTACCATT
CCAGTCCTAGTTCTTTTAGCACTTCAAAGTGACTTGGGGACGGCTTTGGTTTTTGTAGCCATTTTCTCAGGAATCGTTTT
ATTATCAGGGGTTTCTTGGAAAATTATTATCCCAGTATTTGTGACTGCTGTAACAGGAGTTGCTGGTTTCTTAGCTATCT
TTATTAGCAAGGACGGACGAGCTTTTCTTCACCAGATTGGAATGCCGACCTACCAAATCAATCGGATTTTGGCTTGGCTC
AATCCCTTTGAGTTTGCCCAAACAACGACTTACCAGCAGGCTCAAGGGCAGATTGCCATTGGGAGTGGTGGCTTATTTGG
TCAGGGATTTAATGCTTCGAATCTGCTTATCCCAGTTCGAGAGTCAGATATGATTTTTACGGTTATTGCAGAAGATTTTG
GCTTTATTGGCTCTGTCCTGGTTATTGCCCTCTATCTCATGTTGATTTACCGTATGTTGAAGATTACTCTTAAATCAAAT
AACCAGTTCTACACTTATATTTCCACAGGTTTGATTATGATGTTGCTCTTCCACATCTTTGAGAATATCGGTGCTGTGAC
TGGACTACTTCCTTTGACGGGGATTCCCTTGCCTTTCATTTCGCAAGGGGGATCAGCTATTATCAGTAATCTGATTGGTG
TTGGTTTGCTTTTATCGATGAGTTACCAGACTAATCTAGCTGAAGAAAAGAGCGGAAAAGTCCCATTCAAACGGAAAAAG
GTTGTATTAAAACAAATTAAATAA

Upstream 100 bases:

>100_bases
TGTTAAAACCATCTCTCGATCCGAAGTTGACGAGGCTATTGATAGATTTTTTAATGAACTTTGATAAATAGTATTGTATG
AAAGTATAAGGTTAGTATAT

Downstream 100 bases:

>100_bases
GGAGAAAATCATGGTAAAAGTAGCAGTTATGTTAGCTCAGGGCTTTGAAGAAATTGAAGCCTTGACAGTTGTAGATGTCT
TGCGTCGAGCCAATATCACA

Product: RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILG
LGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTYQINRILAWL
NPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSN
NQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKK
VVLKQIK

Sequences:

>Translated_407_residues
MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILG
LGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTYQINRILAWL
NPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSN
NQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKK
VVLKQIK
>Mature_407_residues
MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILG
LGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTYQINRILAWL
NPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSN
NQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKK
VVLKQIK

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=355, Percent_Identity=33.5211267605634, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786277, Length=402, Percent_Identity=25.6218905472637, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45235; Mature: 45235

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFV
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEECCEEEECCHHHHH
ISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTIPVLVLLALQSDLGTALVFVA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTYQINRILAWL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHC
NPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVL
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHH
VIALYLMLIYRMLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFI
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKKVVLKQIK
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFV
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEECCEEEECCHHHHH
ISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTIPVLVLLALQSDLGTALVFVA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTYQINRILAWL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHC
NPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVL
CHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEEEHHHHHHHHHHHH
VIALYLMLIYRMLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFI
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKKVVLKQIK
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]