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The map label for this gene is yheS [H]

Identifier: 225860887

GI number: 225860887

Start: 890061

End: 891587

Strand: Reverse

Name: yheS [H]

Synonym: SPT_0945

Alternate gene names: 225860887

Gene position: 891587-890061 (Counterclockwise)

Preceding gene: 225860888

Following gene: 225860884

Centisome position: 42.21

GC content: 40.54

Gene sequence:

>1527_bases
ATGATAAAAATCAATCACCTGACCATCACACAAAACAAAGATTTACGAGACCTTGTCTCTGACCTAAGCATGACCATACA
AGACGGGGAAAAGGTAGCTATTATTGGCGAAGAAGGAAATGGTAAATCAACCTTACTTAAAACTTTAATGGGGGAAGATT
TGTCTGATTTCACTATCAAGGGAGACATCCAGTCTGATTATCAGTCACTGGCCTACATTCCTCAAAAACTTCCCGAGGAG
CTGAAAAAGAAAACTTTACACGACTACTTCTTTTTAGATTCTATTGATTTAGACTACAGTATCCTCTATCGTTTGGCGGA
GGAATTGCATTTTGATAGCAATCGTTTCGCAAGTGACCAAGAGATTGGCAATCTATCAGGGGGAGAAGCTTTGAAAATTC
AGCTTATCCATGAGTTAGCCAAACCCTTTGAGATTCTATTTTTAGATGAACCTTCAAATGACCTAGACCTTGAGACAGTT
GATTGGTTAAAAGGCCAGATTCAAAAGACCAGGCAAACCGTTATTTTCATTTCCCATGATGAAGACTTTCTTTCTGAAAC
GGCAGACACTATTGTTCACTTGCGACTGGTCAAACACCGTAAAGAAGCGGAAACGCTAGTAGAGCATTTAGACTATGAAA
GCTATAGTGAGCAGAGAAAGGCTAAATTTGCCAAACAAAGTCAGCAAGCTGCTAACAACCAAAGAGCCTACGATAAAACC
ATGGAAAAACATCGGAGAGTCAAACAAAATGTAGAAACTGCGCTTCGAGCTACCAAAGACAGTACTGCCGGTCGCCTATT
GGCTAAAAAGATGAAAACTGTCCTCTCACAAGAAAAACGCTACGAAAAGGCAGCTCAGTCCATGACTCAAAAGCCACTTG
AAGAGGAACAAATCCAACTTTTCTTTTCAGACATCCAACCATTACCAGCTTCTAAAGTCTTAGTCCAACTGGAAAAAGAA
AATTTGTCCATTGACGACCGAGTTTTGGTTCAAAAACTACAACTAACTGTCCGTGGGCAAGAAAAAATCGGTATTATCGG
GCCAAATGGTGTTGGGAAATCAACTCTGTTAGCCAAATTAAAGCAACTTCTGAATGATAAAAGAGAGATTTCCCTTGGTT
TTATGCCACAAGATTACCACAAAAAACTGCAATTGGATTTATCACCAATAGCCTACCTCAGCAAAACTGGGGAAAAAGAG
GAACTACAGAAAATCCAATCTCACCTAGCTAGTCTCAATTTCAGTTATCCAGAAATGCAGCATCAAATTCGCTCCTTATC
TGGCGGACAACAGGGAAAACTCCTGCTTTTGGATTTAGTCCTGCGCAAACCAAACTTTCTCCTGCTGGATGAACCCACAC
GAAACTTTTCTCCCACTTCTCAACCCCAAATCAGAAAACTCTTTGCAACCTATCCAGGCGGTCTCATCACTGTTTCGCAT
GACCGTCGTTTCTTAAAAGAGGTCTGTTCAAGCATCTACCGCTTGACAGAACACGGTTTGGAGTTAGTTAATTTAGAAGA
TGTATAA

Upstream 100 bases:

>100_bases
GGCATGTTAATAGAGTTTTTTTGACATAGACTTTGGGCTCTACTAGGTAAAGTAGAGCTTTTTGTTATGCACTATGAACA
TTCTAGAAAGGGCAATAGTT

Downstream 100 bases:

>100_bases
ATTTGCAACATAGCAAAAATCCAGAGACGACCTCTGGATTCTTTTACATCTGTTTTAAACGTTCAATCCGTTCTGAGATA
GGTGGGTGGGTATAAAAGAG

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEE
LKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETV
DWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYESYSEQRKAKFAKQSQQAANNQRAYDKT
MEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKE
NLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYLSKTGEKE
ELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSH
DRRFLKEVCSSIYRLTEHGLELVNLEDV

Sequences:

>Translated_508_residues
MIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEE
LKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETV
DWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYESYSEQRKAKFAKQSQQAANNQRAYDKT
MEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKE
NLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYLSKTGEKE
ELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSH
DRRFLKEVCSSIYRLTEHGLELVNLEDV
>Mature_508_residues
MIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEE
LKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETV
DWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLVEHLDYESYSEQRKAKFAKQSQQAANNQRAYDKT
MEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKE
NLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHKKLQLDLSPIAYLSKTGEKE
ELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSH
DRRFLKEVCSSIYRLTEHGLELVNLEDV

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27881506, Length=514, Percent_Identity=23.7354085603113, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI148612853, Length=392, Percent_Identity=25.765306122449, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI10947137, Length=514, Percent_Identity=23.7354085603113, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI10947135, Length=391, Percent_Identity=27.3657289002558, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI69354671, Length=391, Percent_Identity=27.3657289002558, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1789751, Length=545, Percent_Identity=28.4403669724771, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI2367384, Length=537, Percent_Identity=28.4916201117318, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1787041, Length=547, Percent_Identity=24.4972577696526, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787182, Length=518, Percent_Identity=25.8687258687259, Blast_Score=135, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17555318, Length=541, Percent_Identity=25.3234750462107, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17553372, Length=532, Percent_Identity=25.7518796992481, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17559834, Length=540, Percent_Identity=25, Blast_Score=133, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321121, Length=548, Percent_Identity=25.5474452554745, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6320874, Length=515, Percent_Identity=24.6601941747573, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323278, Length=193, Percent_Identity=31.6062176165803, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325030, Length=182, Percent_Identity=30.2197802197802, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324314, Length=193, Percent_Identity=31.6062176165803, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24642252, Length=535, Percent_Identity=26.1682242990654, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI18859989, Length=535, Percent_Identity=26.1682242990654, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24666836, Length=394, Percent_Identity=27.1573604060914, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24641342, Length=538, Percent_Identity=25.8364312267658, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24661270, Length=169, Percent_Identity=28.4023668639053, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355589, Length=169, Percent_Identity=28.4023668639053, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 58130; Mature: 58130

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIK
CEEEEEEEEECCCCHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEE
GDIQSDYQSLAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
EIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETVDWLKGQIQKTRQTVIFISHD
CCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
EDFLSETADTIVHLRLVKHRKEAETLVEHLDYESYSEQRKAKFAKQSQQAANNQRAYDKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
MEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKL
HHHHCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHH
KQLLNDKREISLGFMPQDYHKKLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQ
HHHHCCCHHEEECCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
HQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSH
HHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECC
DRRFLKEVCSSIYRLTEHGLELVNLEDV
CHHHHHHHHHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure
MIKINHLTITQNKDLRDLVSDLSMTIQDGEKVAIIGEEGNGKSTLLKTLMGEDLSDFTIK
CEEEEEEEEECCCCHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCEEE
GDIQSDYQSLAYIPQKLPEELKKKTLHDYFFLDSIDLDYSILYRLAEELHFDSNRFASDQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
EIGNLSGGEALKIQLIHELAKPFEILFLDEPSNDLDLETVDWLKGQIQKTRQTVIFISHD
CCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECC
EDFLSETADTIVHLRLVKHRKEAETLVEHLDYESYSEQRKAKFAKQSQQAANNQRAYDKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
MEKHRRVKQNVETALRATKDSTAGRLLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FFSDIQPLPASKVLVQLEKENLSIDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKL
HHHHCCCCCHHHHHEEECCCCCCCHHHHHHHHHHHHEECCCEEEEECCCCCCHHHHHHHH
KQLLNDKREISLGFMPQDYHKKLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQ
HHHHCCCHHEEECCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
HQIRSLSGGQQGKLLLLDLVLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSH
HHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEECC
DRRFLKEVCSSIYRLTEHGLELVNLEDV
CHHHHHHHHHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]