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The map label for this gene is 225859935

Identifier: 225859935

GI number: 225859935

Start: 2104497

End: 2105816

Strand: Reverse

Name: 225859935

Synonym: SP70585_2289

Alternate gene names: NA

Gene position: 2105816-2104497 (Counterclockwise)

Preceding gene: 225859936

Following gene: 225859934

Centisome position: 96.39

GC content: 34.7

Gene sequence:

>1320_bases
ATGAAACATACACTTGAAACTATCAATAGTAGAACTCAGTGGTTTAGAGAAGCAAGATTTGGGATGTTCATTCATTGGGG
GTTATATTCTATTCCAGGAAAAGGGGAATGGATTCGTAGTCATCAGAAATTATCTATTGAAGATTATGAACCATATTTTC
GAGCTTTTGATCCTAAGGAATATAACCCTAGAGAATGGGCTAAACAAGCAAAAGCTGCAGGGATGAAGTATATGGTTTTA
ACGGCTAAACATCATGATGGGTTTTGTTTGTTTGATTCAAAATTTACAGATTATAAAGCAACAAATACACCTGCAGGTAG
AGATTTAGTTAAAGAATTTGTAGATGCTGTTCGAGCTGAAGGTTTAAAAGTAGGCTTATATTTTAGTTTGATTGACTGGC
ACCATCCTGATTTCCCTAAATATGCTGATCTAAATCATCCAATGAGAGGAAATGAAGCCTATCGAGATGAGAAAATTAAC
TTTGACAGTTATTTGGAGTATTTACACAATCAAGTTAAAGAAATTGTAACTGGTTATGGTCAGATTGACATATTATGGTT
TGATTATTCTTATGAAGACATGGTGGGTGAAAAATGGGGAGCTTCAAAATTAATAGACATGGTTCGTCATTATCAGCCAA
ACGTTATCGTAGATAATAGATTAGAAACATCAGGTGAAGGATTCGGAAGTATCGTTACAGATGAAATTACCTCTTACGCT
GGAGATTTTGTTAGTCCAGAGCAAATTGTTCCTCACGAAGGTATTCGAAACTTTAAAGGTGAACCTGTTCCTTGGGAACT
TTGTCTAACTATGAATAACAATTGGGCTTATAATCCTACAGATTATCTATATAAGTCTAGTCAAACTTTGATAAGAAAGT
TAGTGGAATGTGTTAGTAAAAACGGAAATATGATTCTTAATGTAGGCCCAGATGCTTTGGGAAGAATTAATGATTCAAGT
AAGAAAATATTAGATAATTTTCATCGATGGATGTCTCGAAATGGTGAGGCAATTTATGGATGTAGTGGAGATGAAAATTT
ACCAAAACCAGATTGGGGATACTATACTCGTAATGGAAATACGGTTTATGCTCATGTATTTGAACAACCTATAGGTCCTT
TAGCTCTTCTTGGTATTAGTAAAGAAAACGTAAAAAGAATGAGCTTTCTTCATGATGGAAGTGAGGTGAAAATTTCAGAA
AGCTGGACGACCAATGCCTACAAAGGAATTTGTTTTGCACAGTTTGGAGAAGTTCCACATTTTACCTATCCATTACCAGA
CTTGATTGATAGCGTAATCAAAATTGAGTTGAGAGAGTAG

Upstream 100 bases:

>100_bases
TATTTTCAGCTATTGTTGTAATCGTATTACCACCAATCATTCTATTCGCATTTACAAGTAAATACTTCATTGAAGCTTTA
GGAGGAGGAGCAGTAAAAGG

Downstream 100 bases:

>100_bases
TTTATATGAAAATTGAAAATAAAAATGTAAGACGTAATTTCTTTTGGGGAGATGGTCGATTTTATACTACTGATATCGTA
AACAAACGGGCAGGAGTAAT

Product: alpha-L-fucosidase

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Coagulation Factor 5/8 Type Domain Protein; Alpha-L-Fucosidase Protein; Exported Alpha-L-Fucosidase Protein; Calx-Beta Domain-Containing Protein; Glycoside Hydrolase Family Alpha-L-Fucosidase; Lipoprotein; Family; Exporte Hydrolase; Fucosidase; Exported Fucosidase; Alpha-L-Fucosidase Family Protein; Alpha-L-Fucosidase-Like Protein; Twin-Arginine Translocation Pathway Signal; Ig Domain-Containing; Alpha-L-Fucosidase Superfamily; Alpha-1 3/4-Fucosidase; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; DS Domain-Containing Protein; Glycoside Hydrolase

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKLSIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVL
TAKHHDGFCLFDSKFTDYKATNTPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVDNRLETSGEGFGSIVTDEITSYA
GDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWAYNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSS
KKILDNFHRWMSRNGEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHDGSEVKISE
SWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE

Sequences:

>Translated_439_residues
MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKLSIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVL
TAKHHDGFCLFDSKFTDYKATNTPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVDNRLETSGEGFGSIVTDEITSYA
GDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWAYNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSS
KKILDNFHRWMSRNGEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHDGSEVKISE
SWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE
>Mature_439_residues
MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKLSIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVL
TAKHHDGFCLFDSKFTDYKATNTPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
FDSYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVDNRLETSGEGFGSIVTDEITSYA
GDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWAYNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSS
KKILDNFHRWMSRNGEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHDGSEVKISE
SWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40068512, Length=410, Percent_Identity=29.2682926829268, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI119360348, Length=452, Percent_Identity=26.9911504424779, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71997700, Length=364, Percent_Identity=26.6483516483516, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24662717, Length=393, Percent_Identity=27.9898218829517, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI78706642, Length=393, Percent_Identity=27.9898218829517, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 50739; Mature: 50739

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKLSIEDYEPYFRAFDPKE
CCCHHHHHHHHHHHHHHHCCCEEEEECEEECCCCCHHHHCCCCCCCCCCCHHHHCCCCCC
YNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATNTPAGRDLVKEFVDAVRAE
CCHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKINFDSYLEYLHNQVKEIVTGYG
CEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
QIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVDNRLETSGEGFGSIVTDEITSYA
CEEEEEEECCHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
GDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWAYNPTDYLYKSSQTLIRKLVECVSK
CCCCCCHHCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHCC
NGNMILNVGPDALGRINDSSKKILDNFHRWMSRNGEAIYGCSGDENLPKPDWGYYTRNGN
CCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEECCCC
TVYAHVFEQPIGPLALLGISKENVKRMSFLHDGSEVKISESWTTNAYKGICFAQFGEVPH
EEEEEEECCCCCCEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCCCC
FTYPLPDLIDSVIKIELRE
CCCCCHHHHHHHHEEEECC
>Mature Secondary Structure
MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKLSIEDYEPYFRAFDPKE
CCCHHHHHHHHHHHHHHHCCCEEEEECEEECCCCCHHHHCCCCCCCCCCCHHHHCCCCCC
YNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATNTPAGRDLVKEFVDAVRAE
CCHHHHHHHHHHCCCEEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKINFDSYLEYLHNQVKEIVTGYG
CEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
QIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVDNRLETSGEGFGSIVTDEITSYA
CEEEEEEECCHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHHH
GDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWAYNPTDYLYKSSQTLIRKLVECVSK
CCCCCCHHCCCCHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHCC
NGNMILNVGPDALGRINDSSKKILDNFHRWMSRNGEAIYGCSGDENLPKPDWGYYTRNGN
CCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEECCCC
TVYAHVFEQPIGPLALLGISKENVKRMSFLHDGSEVKISESWTTNAYKGICFAQFGEVPH
EEEEEEECCCCCCEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCCCC
FTYPLPDLIDSVIKIELRE
CCCCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA