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The map label for this gene is nag3 [H]

Identifier: 225859880

GI number: 225859880

Start: 2041327

End: 2043051

Strand: Reverse

Name: nag3 [H]

Synonym: SP70585_2233

Alternate gene names: 225859880

Gene position: 2043051-2041327 (Counterclockwise)

Preceding gene: 225859881

Following gene: 225859879

Centisome position: 93.52

GC content: 42.26

Gene sequence:

>1725_bases
ATGCCTAGACTAGTTGATTTAAGAAAGAAACCATATTACTTGAATGATGATCAGATTGTCTGGGTAGAGAGTACCCTTGA
AAATCTGACAGATGAAGAAAAAATTGGCCAACTTTTTGTCAACCTCTTCTTCTTTGGCGGTGATGCCTTTAGCGGGAATA
ATCTGAGCAATCAGGAGCTGATTAATCGATACCACATTGGCGGTGCTCGTTATATGAATGGTAGTCCTGAGCAAGTACAG
GGGCTTATCAATGACTTACAGTCATATTCAAAAGTTCCTCTCCTTGTTGCAGCTAACTGTGATTCCGGTGGAGATGGAGC
TGTGAAAGGTGGAACTTACATTTCTTCAGGTGCCCAGTCTGAAGCCAGTCGTGATTCTCGCATTCCATATCTTGCAGGTC
TTGTATCTGCGAGGGAGGAAACTGCATTGGGTGTCAATGTCAATTTTGACCCATGCGTAGACATCGTTCAAAACTGGCGC
AATACCATTGTGAATACCAGAGCTTATGGGACCAATGCTGACGATGTTATTGCTTATACCAGCGCCTATTTAGAGGGTTT
GACTGCCGAAAGAGATGTTATTCAATGCATAAAACATTTTCCAGGTGATGGGACAGAAGAGCGAGATCAGCACCTAGTTC
TCGGTGTCAATGAGCTATCACCAGAAGAGTGGGACGATAGTTTTGGTCGTGTCTATCACCACCATATTGAAGCTGGTGTA
GAGATGGTTATGGCTGGTCATATCGCCTTGCTATATTATCAACAAAAATTGAACCCTAGTTTAAAGGATGAGGATATCTT
ACCAGCAACACTAGCTCCCGAATTGATTCAAGATTTATTGAAAGAAAAACTGGAATTCAATGGCTTGGTTATTACCGATG
CCAGTCACATGCTGGGGATGACAGCGGCTATGCGTCGCGAAGACTATGTACCAGCTGCCATTGCAGCGGGTTGTGATATG
TTCTTGTTTTTCAATAACCTGGAAGAAGATTTTGAGTTTATGCTGAACGGTTACAGAAATGGCGTGATTACCAAAGAACG
TCTTCATGATGCTCTTCGCCGCATTTTAGGATTGAAAGCCAAACTCAATCTTCATGTCAAACAAGCAGAAGGGACTCTGT
TGAAATCCGCTGATGAGTTGGCAATTATTGGATGTGAAGAACATTTGGCTTGGCAACGTGAGGCGGCAGATAAGGCGATT
ACTCTTTTGAAAGATACCCAACACAATCTTCCAATCAGCCCTGAAACTCATCGAAGGATCCGCTTATATTACTTAGAAGG
GGAAAAAGAGGGGATTATGGCGGCAAGTACAGAAGTAGTAGATAATCTCAAATCCGCCTTGGAAGCGCGTGGCTATGAAG
TGACTGTCAATGATGGTACTACTCGGATTAAAGGAAAAACTCTACAATATCGAGAAGAAGTAGATTTAGCATTGACGGTT
GCCAATGTCATCGGATACGGTGCGCAGAATAATTACCGTATCCAATGGAAAACAGCCATGTCCAATGAAGTTCCTTGGTA
TGTTCATGAAGTATCAACCATCTTTGTTTCTCTCAATTACACTACCCATCTTCACGATGTTACCATGGTGAAAACAGCTA
TCAACGCCTATCACCACAACAAAAATACCATTGAATCCCTCCTTGATAAATTGGAAGGTAAAGATGAGTTCTATGGTATT
CCAAATGAAAATGTTTGGGCCAATAAGTGGCAAGCGAAACTATAA

Upstream 100 bases:

>100_bases
AAACTAGCAGGAGAATCATCGTTTACAGGAGTGTCCCCTGTTGATGCTTACTGTGGCTTGGTAGATACACATATTTGGCG
TGGGAATTAAGGAGACAGCA

Downstream 100 bases:

>100_bases
ATGTAAGCTCCTTTCTATCGTAGATAGAAGGAGTTTTTTAGCAAGATTTCTTGCCAAATGACCTGCATTTTGATAGAATA
TTCTTAATTGAATAGAAGTT

Product: beta-N-acetylglucosaminidase/beta-glucosidase (3-beta-N-acetyl-D-glucosaminidase/beta-D- glucosidase)(Nag3)

Products: NA

Alternate protein names: 3-beta-N-acetyl-D-glucosaminidase/beta-D-glucosidase; Nag3 [H]

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MPRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFFFGGDAFSGNNLSNQELINRYHIGGARYMNGSPEQVQ
GLINDLQSYSKVPLLVAANCDSGGDGAVKGGTYISSGAQSEASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWR
NTIVNTRAYGTNADDVIAYTSAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNELSPEEWDDSFGRVYHHHIEAGV
EMVMAGHIALLYYQQKLNPSLKDEDILPATLAPELIQDLLKEKLEFNGLVITDASHMLGMTAAMRREDYVPAAIAAGCDM
FLFFNNLEEDFEFMLNGYRNGVITKERLHDALRRILGLKAKLNLHVKQAEGTLLKSADELAIIGCEEHLAWQREAADKAI
TLLKDTQHNLPISPETHRRIRLYYLEGEKEGIMAASTEVVDNLKSALEARGYEVTVNDGTTRIKGKTLQYREEVDLALTV
ANVIGYGAQNNYRIQWKTAMSNEVPWYVHEVSTIFVSLNYTTHLHDVTMVKTAINAYHHNKNTIESLLDKLEGKDEFYGI
PNENVWANKWQAKL

Sequences:

>Translated_574_residues
MPRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFFFGGDAFSGNNLSNQELINRYHIGGARYMNGSPEQVQ
GLINDLQSYSKVPLLVAANCDSGGDGAVKGGTYISSGAQSEASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWR
NTIVNTRAYGTNADDVIAYTSAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNELSPEEWDDSFGRVYHHHIEAGV
EMVMAGHIALLYYQQKLNPSLKDEDILPATLAPELIQDLLKEKLEFNGLVITDASHMLGMTAAMRREDYVPAAIAAGCDM
FLFFNNLEEDFEFMLNGYRNGVITKERLHDALRRILGLKAKLNLHVKQAEGTLLKSADELAIIGCEEHLAWQREAADKAI
TLLKDTQHNLPISPETHRRIRLYYLEGEKEGIMAASTEVVDNLKSALEARGYEVTVNDGTTRIKGKTLQYREEVDLALTV
ANVIGYGAQNNYRIQWKTAMSNEVPWYVHEVSTIFVSLNYTTHLHDVTMVKTAINAYHHNKNTIESLLDKLEGKDEFYGI
PNENVWANKWQAKL
>Mature_573_residues
PRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFFFGGDAFSGNNLSNQELINRYHIGGARYMNGSPEQVQG
LINDLQSYSKVPLLVAANCDSGGDGAVKGGTYISSGAQSEASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWRN
TIVNTRAYGTNADDVIAYTSAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNELSPEEWDDSFGRVYHHHIEAGVE
MVMAGHIALLYYQQKLNPSLKDEDILPATLAPELIQDLLKEKLEFNGLVITDASHMLGMTAAMRREDYVPAAIAAGCDMF
LFFNNLEEDFEFMLNGYRNGVITKERLHDALRRILGLKAKLNLHVKQAEGTLLKSADELAIIGCEEHLAWQREAADKAIT
LLKDTQHNLPISPETHRRIRLYYLEGEKEGIMAASTEVVDNLKSALEARGYEVTVNDGTTRIKGKTLQYREEVDLALTVA
NVIGYGAQNNYRIQWKTAMSNEVPWYVHEVSTIFVSLNYTTHLHDVTMVKTAINAYHHNKNTIESLLDKLEGKDEFYGIP
NENVWANKWQAKL

Specific function: Catalyzes the cleavage of beta-N-acetyl-D-glucosaminides and beta-D-glucosides. Might be involved in the degradation of glucuronic acid-containing glycosaminoglycans such as hyaluronic acid [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.21; =3.2.1.52 [H]

Molecular weight: Translated: 64465; Mature: 64334

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFFFGGDAFSGNNLSNQEL
CCCCCCCCCCCEEECCCEEEEEEHHHHCCCCHHHHHHHHHHHHEECCCCCCCCCCCHHHH
INRYHIGGARYMNGSPEQVQGLINDLQSYSKVPLLVAANCDSGGDGAVKGGTYISSGAQS
HHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCCCCC
EASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWRNTIVNTRAYGTNADDVIAYT
CCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
SAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNELSPEEWDDSFGRVYHHHIEAGV
HHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCHHHCHHHHHHHHHHHHHHH
EMVMAGHIALLYYQQKLNPSLKDEDILPATLAPELIQDLLKEKLEFNGLVITDASHMLGM
HHHHHHHEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHH
TAAMRREDYVPAAIAAGCDMFLFFNNLEEDFEFMLNGYRNGVITKERLHDALRRILGLKA
HHHHHHCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCE
KLNLHVKQAEGTLLKSADELAIIGCEEHLAWQREAADKAITLLKDTQHNLPISPETHRRI
EEEEEEEECCCCHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
RLYYLEGEKEGIMAASTEVVDNLKSALEARGYEVTVNDGTTRIKGKTLQYREEVDLALTV
EEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCHHHHHHHHHEEH
ANVIGYGAQNNYRIQWKTAMSNEVPWYVHEVSTIFVSLNYTTHLHDVTMVKTAINAYHHN
HHHHCCCCCCCEEEEEEECCCCCCCEEEEEEEEEEEEEECEEEHHHHHHHHHHHHHHHCC
KNTIESLLDKLEGKDEFYGIPNENVWANKWQAKL
HHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PRLVDLRKKPYYLNDDQIVWVESTLENLTDEEKIGQLFVNLFFFGGDAFSGNNLSNQEL
CCCCCCCCCCEEECCCEEEEEEHHHHCCCCHHHHHHHHHHHHEECCCCCCCCCCCHHHH
INRYHIGGARYMNGSPEQVQGLINDLQSYSKVPLLVAANCDSGGDGAVKGGTYISSGAQS
HHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEECCCCCC
EASRDSRIPYLAGLVSAREETALGVNVNFDPCVDIVQNWRNTIVNTRAYGTNADDVIAYT
CCCCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
SAYLEGLTAERDVIQCIKHFPGDGTEERDQHLVLGVNELSPEEWDDSFGRVYHHHIEAGV
HHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCHHHCHHHHHHHHHHHHHHH
EMVMAGHIALLYYQQKLNPSLKDEDILPATLAPELIQDLLKEKLEFNGLVITDASHMLGM
HHHHHHHEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHH
TAAMRREDYVPAAIAAGCDMFLFFNNLEEDFEFMLNGYRNGVITKERLHDALRRILGLKA
HHHHHHCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCE
KLNLHVKQAEGTLLKSADELAIIGCEEHLAWQREAADKAITLLKDTQHNLPISPETHRRI
EEEEEEEECCCCHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
RLYYLEGEKEGIMAASTEVVDNLKSALEARGYEVTVNDGTTRIKGKTLQYREEVDLALTV
EEEEEECCCCCCEEHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCHHHHHHHHHEEH
ANVIGYGAQNNYRIQWKTAMSNEVPWYVHEVSTIFVSLNYTTHLHDVTMVKTAINAYHHN
HHHHCCCCCCCEEEEEEECCCCCCCEEEEEEEEEEEEEECEEEHHHHHHHHHHHHHHHCC
KNTIESLLDKLEGKDEFYGIPNENVWANKWQAKL
HHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA