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The map label for this gene is tarJ [H]

Identifier: 225859064

GI number: 225859064

Start: 1236211

End: 1237233

Strand: Reverse

Name: tarJ [H]

Synonym: SP70585_1333

Alternate gene names: 225859064

Gene position: 1237233-1236211 (Counterclockwise)

Preceding gene: 225859065

Following gene: 225859063

Centisome position: 56.63

GC content: 40.08

Gene sequence:

>1023_bases
ATGATTAATCAAATTTATCAACTAACTAAGCCTAAGTTTATCAATGTCAAATATCAGGAAGAGGCTATTGACCAAGAGAA
TCATATCCTTATCCGTCCCAACTACATGGCTGTCTGTCATGCGGATCAGCGTTACTATCAGGGAAAACGTGATCCCAAGA
TTTTGAATAAAAAGCTTCCAATGGCAATGATTCACGAGTCATGTGGAAGCGTCATTTCTGACCCGACCGGAACCTACGAG
GTTGGTCAAAAAGTTGTCATGATTCCCAATCAGTCTCCTATGCAGAGTGATGAAGAATTCTATGAAAACTACATGACAGG
GACCCATTTCTTGTCTAGTGGATTTGATGGCTTTATGAGAGAGTTTGTTTCTCTCCCTAAAGATCGTGTGGTGGCTTATG
ATGCTATTGAAGATACGGTTGCAGCCATTACAGAGTTTGTCAGTGTGGGCATGCACGCTATGAATCGTCTATTGACTCTT
GCTCATAGCAAGCGGGAGCGGATCGCCGTTATTGGAGATGGAAGTTTAGCTTTTGTGGTTGCCAATATTATCAACTATAC
TTTGCCAGAATCAGAGATTGTGGTTATTGGTCGTCATTGGGAAAAGTTGGAACTCTTCTCATTTGCCAAAGAATGCTATA
TTACGGATAATATTCCTGAAGAGTTGGCCTTTGACCATGCTTTTGAATGTTGTGGTGGTGATGGTACTGGACCAGCTATT
AATGACTTGATTCGCTACATTCGTCCTCAGGGAACGATTCTCATGATGGGAGTTAGCGAATATAAAGTCAATCTCAATAC
TCGCGATGCCTTAGAAAAGGGCTTGATTTTGGTTGGGTCATCTCGTTCTGGTCGCATTGATTTTAAAAATGCTATCCAAA
TGATGGAAGTCAAGAAATTTGCCAATCGTCTTAAAAATATCCTTTATCTAGAAGAACCTGTAAGAGAAATTAAAGATATT
CATCGTGTCTTTGCAACCGATTTAAACACAGCCTTTAAAACAGTGTTTAAGTGGGAAGTATAA

Upstream 100 bases:

>100_bases
AAAGATGTGGCCTTGGCCAAAGGTGAATACTCAAATCTGAAGATTACAACCGTAACAGATTTGAAGATTGCAAAAAGTAT
GATTGAGAAAGACTAGTAAA

Downstream 100 bases:

>100_bases
GTACTGGAGGTTAATTGTGGAGAAAATCATTAAAGAAAAAATTTCTTCCTTACTTAGTCAAGAAGAGGAAGTCCTCAGTG
TTGAACAACTGGGTGGAATG

Product: xylitol dehydrogenase

Products: NA

Alternate protein names: Ribulose-5-P reductase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQRYYQGKRDPKILNKKLPMAMIHESCGSVISDPTGTYE
VGQKVVMIPNQSPMQSDEEFYENYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNIPEELAFDHAFECCGGDGTGPAI
NDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLILVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDI
HRVFATDLNTAFKTVFKWEV

Sequences:

>Translated_340_residues
MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQRYYQGKRDPKILNKKLPMAMIHESCGSVISDPTGTYE
VGQKVVMIPNQSPMQSDEEFYENYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNIPEELAFDHAFECCGGDGTGPAI
NDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLILVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDI
HRVFATDLNTAFKTVFKWEV
>Mature_340_residues
MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQRYYQGKRDPKILNKKLPMAMIHESCGSVISDPTGTYE
VGQKVVMIPNQSPMQSDEEFYENYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNIPEELAFDHAFECCGGDGTGPAI
NDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLILVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDI
HRVFATDLNTAFKTVFKWEV

Specific function: Catalyzes the conversion of ribulose 5-P to ribitol 5-P (Potential) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319955, Length=324, Percent_Identity=22.8395061728395, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=324, Percent_Identity=22.8395061728395, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.137 [H]

Molecular weight: Translated: 38786; Mature: 38786

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQRYYQGKRDPKILNKKLP
CCCHHHHHCCCEEEEEEEHHHHCCCCCEEEECCCEEEEEECHHHHHCCCCCHHHHHHCCC
MAMIHESCGSVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYENYMTGTHFLSSGFDGFMR
HHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
EFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTLAHSKRERIAVIGDGSLAFVV
HHHHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
ANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNIPEELAFDHAFECCGGDGTGPAI
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCHHH
NDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLILVGSSRSGRIDFKNAIQMMEVKKF
HHHHHHHCCCCCEEEEEEEHEEEECCHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHH
ANRLKNILYLEEPVREIKDIHRVFATDLNTAFKTVFKWEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQRYYQGKRDPKILNKKLP
CCCHHHHHCCCEEEEEEEHHHHCCCCCEEEECCCEEEEEECHHHHHCCCCCHHHHHHCCC
MAMIHESCGSVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYENYMTGTHFLSSGFDGFMR
HHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
EFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTLAHSKRERIAVIGDGSLAFVV
HHHHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHH
ANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNIPEELAFDHAFECCGGDGTGPAI
HHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCHHH
NDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLILVGSSRSGRIDFKNAIQMMEVKKF
HHHHHHHCCCCCEEEEEEEHEEEECCHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHH
ANRLKNILYLEEPVREIKDIHRVFATDLNTAFKTVFKWEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11882717 [H]