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The map label for this gene is ung

Identifier: 225858955

GI number: 225858955

Start: 1132401

End: 1133069

Strand: Reverse

Name: ung

Synonym: SP70585_1220

Alternate gene names: 225858955

Gene position: 1133069-1132401 (Counterclockwise)

Preceding gene: 225858956

Following gene: 225858954

Centisome position: 51.86

GC content: 44.54

Gene sequence:

>669_bases
ATGAAGGAGTTGGCTATGGAACACTCGTCTTGGCACGCTTTGATTAAGGCGCAATTACCTGAGGGTTATTTCGGGAAAAT
CAATCAGTTTATGGAGCAGGTCTATTCTCAGGGGACTATTTATCCACCCAAGGAAAAGGTTTTTCAGGCTCTCTTGACAA
CACTGCTTGAAGAAGTTAAGGTGGTAATTCTAGGGCAAGACCCCTACCACGGACCAGGTCAAGCGCAGGGCTTGAGTTTT
TCTGTACCTGACTCTATCCCAGCTCCACCATCCTTGCAAAATATCTTGAAAGAATTGTCAGATGATATCGGAGTTAAGAA
ATCTCATGATTTGACAGCTTGGGCTGAGCAAGGAGTCTTGCTTCTTAATGCTTGTTTGACTGTTCCTGCTGGACAGGCCA
ATGGTCATGCTGGTCAAATCTGGGAGCCTTTTACTGATGCTGTGATTCAGGTGGTCAATCATCTAGATAGACCAGTCGTT
TTTGTACTCTGGGGAGCTTATGCACGTAAGAAGAAGGCATTAGTTACCAATCCTCATCACTTGATTATCGAATCAGCCCA
TCCAAGTCCTTTGTCGGTTTATAGAGGATTTTGGGGTTCCAAGCCCTTTTCCAAGGCCAATGCATTCTTAAAAGAGACAG
GACAAGAGCCAATCGATTGGCTTAGATAA

Upstream 100 bases:

>100_bases
ACGTATTCAAATCGTATATATAGTCGATTTATTAAATCTTTAGATAAACTGTAAAAAGTGGTTTCCATAGCCACTTTTTG
CTATAATAGAGGCAGTAAAA

Downstream 100 bases:

>100_bases
GGAGAAAATATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAA
ACCCAATGATGTCCATGAAG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKELAMEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQALLTTLLEEVKVVILGQDPYHGPGQAQGLSF
SVPDSIPAPPSLQNILKELSDDIGVKKSHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVV
FVLWGAYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR

Sequences:

>Translated_222_residues
MKELAMEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQALLTTLLEEVKVVILGQDPYHGPGQAQGLSF
SVPDSIPAPPSLQNILKELSDDIGVKKSHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVV
FVLWGAYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR
>Mature_222_residues
MKELAMEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQALLTTLLEEVKVVILGQDPYHGPGQAQGLSF
SVPDSIPAPPSLQNILKELSDDIGVKKSHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVV
FVLWGAYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=214, Percent_Identity=50.9345794392523, Blast_Score=214, Evalue=6e-56,
Organism=Homo sapiens, GI6224979, Length=214, Percent_Identity=50.9345794392523, Blast_Score=213, Evalue=7e-56,
Organism=Escherichia coli, GI1788934, Length=216, Percent_Identity=49.0740740740741, Blast_Score=200, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=44.9074074074074, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6323620, Length=238, Percent_Identity=41.5966386554622, Blast_Score=162, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24611; Mature: 24611

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELAMEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQALLTTLLEEVK
CCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHE
VVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKKSHDLTAWAEQGVL
EEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHH
LLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWGAYARKKKALVTNPHH
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCEECCCCE
LIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR
EEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MKELAMEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGTIYPPKEKVFQALLTTLLEEVK
CCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHE
VVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKKSHDLTAWAEQGVL
EEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHH
LLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWGAYARKKKALVTNPHH
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCEECCCCE
LIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR
EEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA