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The map label for this gene is comM [H]

Identifier: 225853560

GI number: 225853560

Start: 2074929

End: 2076485

Strand: Direct

Name: comM [H]

Synonym: BMEA_A2194

Alternate gene names: 225853560

Gene position: 2074929-2076485 (Clockwise)

Preceding gene: 225853559

Following gene: 225853563

Centisome position: 97.61

GC content: 62.36

Gene sequence:

>1557_bases
GTGCTGCGTGGCAAGCGGGGGCTCATGGTCGCGCGGGTTGGAACAGTTGCCTTTCATGGCATAGAGGCGGTGCCTGTCGA
TGTGCAGGTGATGATCGCGCCGGGCAAGATGGGCATGTCCATCGTCGGGCTGCCCGACAAGGCTGTGGCCGAAAGCCGGG
AGCGGGTGCAGGCTGCACTGCACGCATCCGGGCTTTCCATGCCCGCCAAGCGGGTGACGGTCAATCTCGCTCCTGCCGAT
CTTCCGAAGGAAGGTTCGCATTACGACCTTCCCATCGCTGTCGGCCTGATGGCCGCAATGGGGGCCATTCCCGCCGATGC
CATTCAATCCTATCTTGTGCTGGGCGAATTGTCGCTTGATGGTTCCATCACGGCGGTTGCGGGCGTTCTTCCTGCTGCAA
TAGGCGCCAATCGCGGGGAAAAGGGCCTGATCTGCCCCCATGCCTGCGGGCCGGAGGCGGCATGGGCGGGCGCCAATATC
GATATTCTCGCGCCGCGAAGCCTGATCGCACTCGCCAATCATTTCCGCGGGACGCAAGTGCTGACGCCGCCCGATCCTTC
CATGCGCCTTTCCAGCGAGGCACTGCCTGATCTTTCCGATATCAAGGGGCAGGAAACGGCAAAGCGCGCGCTGGAAATCG
CTGCGGCCGGAAACCATAACCTGCTTCTTGTCGGCCCGCCCGGATCGGGTAAATCCATGCTGGCGTCGCGCCTGCCGTCC
ATCCTGCCCAGGCTTTCTCCGCGTGAATTGCTGGATGTTTCGATGATCGCTTCGATAGCTGGAGAGCTATCGGGCGGGAA
ACTGTCGGATCGCAGGCCGTTTCGTGCGCCGCATCATTCTGCTTCGATGGCTGCAATGGTTGGTGGTGGATTGCGCGCAA
GGCCGGGCGAGGTGTCGCTTGCCCATAATGGCGTGCTGTTTCTGGACGAGTTTCCTGAATTCTCGCCGCAGGTGCTGGAT
TCACTGCGCCAGCCGCTGGAAACCGGCGAATGCCTGATCGCGCGCGTCAACCATCGCACCAGCTATCCGGCGCGCTTTCA
ATTGATTGCCGCCATGAACCCATGCCGCTGCGGCATGGCGGGCGAACCGGGGCATACATGCGCGCGGGGTCCACGTTGCC
AGAGCGACTATCAGGCGCGCATTTCCGGCCCCCTGCTCGACCGTATCGATCTGCGTGTCGATATGCCGGCGGTTTCTGCG
CTCGATCTGATCGCGCCCGGCCAGTCGGAGAAAAGTGAGACGGTCGCAAGGCGCGTGGCGCGCGCACGCGCCGTTCAGGC
CGCGCGCTATGGCGCGCTCGGTCTCGATCCATCAATGACCAACGCCTATTGTTCGGCAAACCTGATCGAGGAGGTCGCCC
GGCCCGATGCCGCAGGCATGAAATTATTGCGTGATGCAAGCGAGCAGATGCGCTTTTCAGCCCGTGCCTATCACCGCATA
CTGAAAGTGGCGCGCACCCTTGCCGATCTCGATGGAAGCGATCATGTCACCCGCATCCATCTGGCCGGCGCCATATCCTA
TCGCATGGGCGCAGAGCGCTTGGTTTCAGCAGCATGA

Upstream 100 bases:

>100_bases
GAAGCCAGACGATAATTTGTTCCTGAAACGTTCTTGACCTCACCAATAGTATATGCTTAACTCCAGAAGTTGTATTTAAG
CATATACTCACTTGTAGGAT

Downstream 100 bases:

>100_bases
AAGGGCTGGATGCAAAAAAGGCGGTGAGAAACCCACCGCCAGTTCAACTCAGCGGACCGAGCCGACCAGAAGATTGTCCG
GGGCTTCGATTGTGACCCAA

Product: Mg chelatase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLRGKRGLMVARVGTVAFHGIEAVPVDVQVMIAPGKMGMSIVGLPDKAVAESRERVQAALHASGLSMPAKRVTVNLAPAD
LPKEGSHYDLPIAVGLMAAMGAIPADAIQSYLVLGELSLDGSITAVAGVLPAAIGANRGEKGLICPHACGPEAAWAGANI
DILAPRSLIALANHFRGTQVLTPPDPSMRLSSEALPDLSDIKGQETAKRALEIAAAGNHNLLLVGPPGSGKSMLASRLPS
ILPRLSPRELLDVSMIASIAGELSGGKLSDRRPFRAPHHSASMAAMVGGGLRARPGEVSLAHNGVLFLDEFPEFSPQVLD
SLRQPLETGECLIARVNHRTSYPARFQLIAAMNPCRCGMAGEPGHTCARGPRCQSDYQARISGPLLDRIDLRVDMPAVSA
LDLIAPGQSEKSETVARRVARARAVQAARYGALGLDPSMTNAYCSANLIEEVARPDAAGMKLLRDASEQMRFSARAYHRI
LKVARTLADLDGSDHVTRIHLAGAISYRMGAERLVSAA

Sequences:

>Translated_518_residues
MLRGKRGLMVARVGTVAFHGIEAVPVDVQVMIAPGKMGMSIVGLPDKAVAESRERVQAALHASGLSMPAKRVTVNLAPAD
LPKEGSHYDLPIAVGLMAAMGAIPADAIQSYLVLGELSLDGSITAVAGVLPAAIGANRGEKGLICPHACGPEAAWAGANI
DILAPRSLIALANHFRGTQVLTPPDPSMRLSSEALPDLSDIKGQETAKRALEIAAAGNHNLLLVGPPGSGKSMLASRLPS
ILPRLSPRELLDVSMIASIAGELSGGKLSDRRPFRAPHHSASMAAMVGGGLRARPGEVSLAHNGVLFLDEFPEFSPQVLD
SLRQPLETGECLIARVNHRTSYPARFQLIAAMNPCRCGMAGEPGHTCARGPRCQSDYQARISGPLLDRIDLRVDMPAVSA
LDLIAPGQSEKSETVARRVARARAVQAARYGALGLDPSMTNAYCSANLIEEVARPDAAGMKLLRDASEQMRFSARAYHRI
LKVARTLADLDGSDHVTRIHLAGAISYRMGAERLVSAA
>Mature_518_residues
MLRGKRGLMVARVGTVAFHGIEAVPVDVQVMIAPGKMGMSIVGLPDKAVAESRERVQAALHASGLSMPAKRVTVNLAPAD
LPKEGSHYDLPIAVGLMAAMGAIPADAIQSYLVLGELSLDGSITAVAGVLPAAIGANRGEKGLICPHACGPEAAWAGANI
DILAPRSLIALANHFRGTQVLTPPDPSMRLSSEALPDLSDIKGQETAKRALEIAAAGNHNLLLVGPPGSGKSMLASRLPS
ILPRLSPRELLDVSMIASIAGELSGGKLSDRRPFRAPHHSASMAAMVGGGLRARPGEVSLAHNGVLFLDEFPEFSPQVLD
SLRQPLETGECLIARVNHRTSYPARFQLIAAMNPCRCGMAGEPGHTCARGPRCQSDYQARISGPLLDRIDLRVDMPAVSA
LDLIAPGQSEKSETVARRVARARAVQAARYGALGLDPSMTNAYCSANLIEEVARPDAAGMKLLRDASEQMRFSARAYHRI
LKVARTLADLDGSDHVTRIHLAGAISYRMGAERLVSAA

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=499, Percent_Identity=43.687374749499, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54575; Mature: 54575

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGKRGLMVARVGTVAFHGIEAVPVDVQVMIAPGKMGMSIVGLPDKAVAESRERVQAAL
CCCCCCCEEEEEEHHHHHCCCEECCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
HASGLSMPAKRVTVNLAPADLPKEGSHYDLPIAVGLMAAMGAIPADAIQSYLVLGELSLD
HHCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEEEECCC
GSITAVAGVLPAAIGANRGEKGLICPHACGPEAAWAGANIDILAPRSLIALANHFRGTQV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCEE
LTPPDPSMRLSSEALPDLSDIKGQETAKRALEIAAAGNHNLLLVGPPGSGKSMLASRLPS
ECCCCCCCCCCHHCCCCHHHCCCHHHHHHHHHHEECCCCCEEEEECCCCCHHHHHHHHHH
ILPRLSPRELLDVSMIASIAGELSGGKLSDRRPFRAPHHSASMAAMVGGGLRARPGEVSL
HHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEE
AHNGVLFLDEFPEFSPQVLDSLRQPLETGECLIARVNHRTSYPARFQLIAAMNPCRCGMA
ECCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHEEEEEECCCCCCCCC
GEPGHTCARGPRCQSDYQARISGPLLDRIDLRVDMPAVSALDLIAPGQSEKSETVARRVA
CCCCCCCCCCCCCCCCHHHHCCCCCHHHCCEEECCCCHHHHHHCCCCCCCHHHHHHHHHH
RARAVQAARYGALGLDPSMTNAYCSANLIEEVARPDAAGMKLLRDASEQMRFSARAYHRI
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKVARTLADLDGSDHVTRIHLAGAISYRMGAERLVSAA
HHHHHHHHHCCCCCCEEEEEEEHHHHHHHCHHHHHHCC
>Mature Secondary Structure
MLRGKRGLMVARVGTVAFHGIEAVPVDVQVMIAPGKMGMSIVGLPDKAVAESRERVQAAL
CCCCCCCEEEEEEHHHHHCCCEECCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHH
HASGLSMPAKRVTVNLAPADLPKEGSHYDLPIAVGLMAAMGAIPADAIQSYLVLGELSLD
HHCCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEEEECCC
GSITAVAGVLPAAIGANRGEKGLICPHACGPEAAWAGANIDILAPRSLIALANHFRGTQV
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCEE
LTPPDPSMRLSSEALPDLSDIKGQETAKRALEIAAAGNHNLLLVGPPGSGKSMLASRLPS
ECCCCCCCCCCHHCCCCHHHCCCHHHHHHHHHHEECCCCCEEEEECCCCCHHHHHHHHHH
ILPRLSPRELLDVSMIASIAGELSGGKLSDRRPFRAPHHSASMAAMVGGGLRARPGEVSL
HHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEE
AHNGVLFLDEFPEFSPQVLDSLRQPLETGECLIARVNHRTSYPARFQLIAAMNPCRCGMA
ECCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHEEEEEECCCCCCCCC
GEPGHTCARGPRCQSDYQARISGPLLDRIDLRVDMPAVSALDLIAPGQSEKSETVARRVA
CCCCCCCCCCCCCCCCHHHHCCCCCHHHCCEEECCCCHHHHHHCCCCCCCHHHHHHHHHH
RARAVQAARYGALGLDPSMTNAYCSANLIEEVARPDAAGMKLLRDASEQMRFSARAYHRI
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LKVARTLADLDGSDHVTRIHLAGAISYRMGAERLVSAA
HHHHHHHHHCCCCCCEEEEEEEHHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]