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The map label for this gene is exuT [H]

Identifier: 225853399

GI number: 225853399

Start: 1910927

End: 1912234

Strand: Direct

Name: exuT [H]

Synonym: BMEA_A2020

Alternate gene names: 225853399

Gene position: 1910927-1912234 (Clockwise)

Preceding gene: 225853396

Following gene: 225853403

Centisome position: 89.9

GC content: 54.13

Gene sequence:

>1308_bases
GTGAATCCGCTTTTGAAACCCGAGGGGCCGACATCCTATCGGTATGTTATCTTTGCAATCGTCACCATTCTTGCATTGGT
GAATTATATCGACCGCGGCGCAATCTCTTATGCGTCAGAGCAGATCATCGGCGAGTATGGCTTCAACCGGGCCGACTGGG
GTAGCATGCTCGGCTATTTCGGCTATGGTTATATGTTTGGCGCAATCCTCGGCGGCACGCTTTCCGACAAGCTGGGTGCG
CGCAAGTTGTGGATCATCGCGGGTACGGCTTGGTCGATTGTTGCTGTCTCGATGATTTGGGCGGGAGAACTGGGCATCCT
GGCGTTCGGTGGCTCGGCGCTGGCAGGCTTTGCCGTCGTCCGCATTCTTTTCGGTTTCAGCGAAGGCCCGGCCTATTCCA
TCATCAACAAGACCATGGGGAATTGGGCGCCCCGTTCCGAACGCGGTTTTGCCGTCGCCCTTGGCCTTTTGAGCACACCG
CTTGGCGCCATGTTAACCGCGCCGATCGCTGTCGGCCTCCTTCTGGTAACCGGTTCCTGGCGCAGCATGTATATTGTTCT
GGGCGCTCTCGGTCTGATTTTGATCGTGATCTTTTCCAGGATTTATACCAATCGTCCAGAGGACCATCCAAAGGTATCTG
AAGAGGAAGTCCGGTTAATCCGGGCTGGGGGCGAAGTACAAAGCAGCAGCGCAAAATCACACGGTTTTGACCTGAAGGGC
TTCATCTCCAACAAAACGCTCGTTTTCAACTCCATCGGCTACTTCGCGTTTCAGTACGTGAACTTCATGATCCTGACCTG
GACGCCGAAATATCTCTCCGATGAGTTTGGCCTCACGCTTTCCTCGCTTTGGTATATGGGCATGGTCCCCTGGGTGGGCG
CATGTGTAACCATCCTTCTGGGCGGTAAAATCAGCGACTGGCTCTTCCTCAAGACGGGCAAGCTGCGTCTGGCGCGCGGT
GGTCTGGCTGCAGCTTCACTTGCCATTACGACAGCCGTTCTATTGATGATCCCGCATGCGGGATCGGCATGGGGAGTGAT
CGGTCTTATGACTCTGGCAAATGCCTGCAACTCTCTGCCAAATTCAGTATATTGGGCTGTAATCATCGATAGTTCGCCGA
CTGATAAAATGGGTACCTATAGTGGCATCACCCACTTTATTGCCAATATCGCGACAATCCTGTCACCGACCTTGGCGGGT
ATTCTCGCAATGTCATACGGCTATAATGCCATGTTCGTTGCCACGGCCGTGGCAACCGCTATCGGTATGATTGCGATGTT
GTCGGTTAAACCGGGTCAGCGGGTCTGA

Upstream 100 bases:

>100_bases
GTGCCGATAGAAATTAAAGACATTTCCAACTCCCTAAAATTATGCATAATGCATTATCCATATTTGAGTTTTGTATAGGA
ATCAACACGGGGAGGTCTAT

Downstream 100 bases:

>100_bases
TGAGGCTCTCTTCCAAAGCCGTCCCTTTCTGCCAAAAGCATCGGGATTTCTCCGATCTTTTGCTTCAAGGCATTTATGGA
CGCAAAAACCGCTTCGCCCT

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MNPLLKPEGPTSYRYVIFAIVTILALVNYIDRGAISYASEQIIGEYGFNRADWGSMLGYFGYGYMFGAILGGTLSDKLGA
RKLWIIAGTAWSIVAVSMIWAGELGILAFGGSALAGFAVVRILFGFSEGPAYSIINKTMGNWAPRSERGFAVALGLLSTP
LGAMLTAPIAVGLLLVTGSWRSMYIVLGALGLILIVIFSRIYTNRPEDHPKVSEEEVRLIRAGGEVQSSSAKSHGFDLKG
FISNKTLVFNSIGYFAFQYVNFMILTWTPKYLSDEFGLTLSSLWYMGMVPWVGACVTILLGGKISDWLFLKTGKLRLARG
GLAAASLAITTAVLLMIPHAGSAWGVIGLMTLANACNSLPNSVYWAVIIDSSPTDKMGTYSGITHFIANIATILSPTLAG
ILAMSYGYNAMFVATAVATAIGMIAMLSVKPGQRV

Sequences:

>Translated_435_residues
MNPLLKPEGPTSYRYVIFAIVTILALVNYIDRGAISYASEQIIGEYGFNRADWGSMLGYFGYGYMFGAILGGTLSDKLGA
RKLWIIAGTAWSIVAVSMIWAGELGILAFGGSALAGFAVVRILFGFSEGPAYSIINKTMGNWAPRSERGFAVALGLLSTP
LGAMLTAPIAVGLLLVTGSWRSMYIVLGALGLILIVIFSRIYTNRPEDHPKVSEEEVRLIRAGGEVQSSSAKSHGFDLKG
FISNKTLVFNSIGYFAFQYVNFMILTWTPKYLSDEFGLTLSSLWYMGMVPWVGACVTILLGGKISDWLFLKTGKLRLARG
GLAAASLAITTAVLLMIPHAGSAWGVIGLMTLANACNSLPNSVYWAVIIDSSPTDKMGTYSGITHFIANIATILSPTLAG
ILAMSYGYNAMFVATAVATAIGMIAMLSVKPGQRV
>Mature_435_residues
MNPLLKPEGPTSYRYVIFAIVTILALVNYIDRGAISYASEQIIGEYGFNRADWGSMLGYFGYGYMFGAILGGTLSDKLGA
RKLWIIAGTAWSIVAVSMIWAGELGILAFGGSALAGFAVVRILFGFSEGPAYSIINKTMGNWAPRSERGFAVALGLLSTP
LGAMLTAPIAVGLLLVTGSWRSMYIVLGALGLILIVIFSRIYTNRPEDHPKVSEEEVRLIRAGGEVQSSSAKSHGFDLKG
FISNKTLVFNSIGYFAFQYVNFMILTWTPKYLSDEFGLTLSSLWYMGMVPWVGACVTILLGGKISDWLFLKTGKLRLARG
GLAAASLAITTAVLLMIPHAGSAWGVIGLMTLANACNSLPNSVYWAVIIDSSPTDKMGTYSGITHFIANIATILSPTLAG
ILAMSYGYNAMFVATAVATAIGMIAMLSVKPGQRV

Specific function: Aldohexuronate transport system [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=279, Percent_Identity=22.9390681003584, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI154350196, Length=410, Percent_Identity=22.1951219512195, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI9966811, Length=392, Percent_Identity=20.9183673469388, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI9945322, Length=368, Percent_Identity=22.8260869565217, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4885441, Length=319, Percent_Identity=24.7648902821317, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI148743791, Length=364, Percent_Identity=22.5274725274725, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI21322234, Length=296, Percent_Identity=24.3243243243243, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789152, Length=432, Percent_Identity=26.6203703703704, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1789515, Length=426, Percent_Identity=26.2910798122066, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87082320, Length=434, Percent_Identity=27.1889400921659, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI2367379, Length=405, Percent_Identity=24.4444444444444, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI2367193, Length=435, Percent_Identity=22.2988505747126, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=379, Percent_Identity=23.2189973614776, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17532009, Length=264, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193208223, Length=260, Percent_Identity=26.5384615384615, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533871, Length=234, Percent_Identity=23.5042735042735, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561498, Length=202, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20130167, Length=367, Percent_Identity=24.7956403269755, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24584153, Length=365, Percent_Identity=24.6575342465753, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641682, Length=198, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24648416, Length=380, Percent_Identity=25.5263157894737, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356189, Length=380, Percent_Identity=25.5263157894737, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583789, Length=373, Percent_Identity=24.1286863270777, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573299, Length=400, Percent_Identity=24, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45550460, Length=398, Percent_Identity=23.8693467336683, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24655255, Length=384, Percent_Identity=23.6979166666667, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654215, Length=273, Percent_Identity=24.5421245421245, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922400, Length=273, Percent_Identity=24.5421245421245, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46555; Mature: 46555

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLLKPEGPTSYRYVIFAIVTILALVNYIDRGAISYASEQIIGEYGFNRADWGSMLGYF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
GYGYMFGAILGGTLSDKLGARKLWIIAGTAWSIVAVSMIWAGELGILAFGGSALAGFAVV
HHHHHHHHHHCCCHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
RILFGFSEGPAYSIINKTMGNWAPRSERGFAVALGLLSTPLGAMLTAPIAVGLLLVTGSW
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHEECCH
RSMYIVLGALGLILIVIFSRIYTNRPEDHPKVSEEEVRLIRAGGEVQSSSAKSHGFDLKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEE
FISNKTLVFNSIGYFAFQYVNFMILTWTPKYLSDEFGLTLSSLWYMGMVPWVGACVTILL
EECCCEEEEHHHHHHHHHHHCEEEEEECHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHH
GGKISDWLFLKTGKLRLARGGLAAASLAITTAVLLMIPHAGSAWGVIGLMTLANACNSLP
CCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
NSVYWAVIIDSSPTDKMGTYSGITHFIANIATILSPTLAGILAMSYGYNAMFVATAVATA
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IGMIAMLSVKPGQRV
HHHHHHEECCCCCCC
>Mature Secondary Structure
MNPLLKPEGPTSYRYVIFAIVTILALVNYIDRGAISYASEQIIGEYGFNRADWGSMLGYF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
GYGYMFGAILGGTLSDKLGARKLWIIAGTAWSIVAVSMIWAGELGILAFGGSALAGFAVV
HHHHHHHHHHCCCHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHH
RILFGFSEGPAYSIINKTMGNWAPRSERGFAVALGLLSTPLGAMLTAPIAVGLLLVTGSW
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHEECCH
RSMYIVLGALGLILIVIFSRIYTNRPEDHPKVSEEEVRLIRAGGEVQSSSAKSHGFDLKG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEE
FISNKTLVFNSIGYFAFQYVNFMILTWTPKYLSDEFGLTLSSLWYMGMVPWVGACVTILL
EECCCEEEEHHHHHHHHHHHCEEEEEECHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHH
GGKISDWLFLKTGKLRLARGGLAAASLAITTAVLLMIPHAGSAWGVIGLMTLANACNSLP
CCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
NSVYWAVIIDSSPTDKMGTYSGITHFIANIATILSPTLAGILAMSYGYNAMFVATAVATA
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IGMIAMLSVKPGQRV
HHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]