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The map label for this gene is yleA [C]

Identifier: 225853371

GI number: 225853371

Start: 1883112

End: 1884395

Strand: Direct

Name: yleA [C]

Synonym: BMEA_A1990

Alternate gene names: 225853371

Gene position: 1883112-1884395 (Clockwise)

Preceding gene: 225853370

Following gene: 225853372

Centisome position: 88.59

GC content: 60.12

Gene sequence:

>1284_bases
ATGTCTGTGGAAATCGTCACCTTCGGATGCCGCCTCAACACCTATGAATCGGAAGTGATGAGGCGCGAAGCCGACGCTGC
CGGGCTGGGCACGCTGAAAGACGGCGCGATCATCTTCAACACCTGCGCAGTGACGGCGGAAGCGGTGCGCCAGGCGCGCC
AGGCAATTCGCAAGGCGCGCCGTGAAAACCCTGACGCGCGCATCATCGTCACCGGCTGCGCCGCACAGACCGAAGCCGAC
AATTTCGCCGCCATGGGCGAAGTGGACCTTGTCCTCGGCAATGAGGAGAAGCTGAAATCCAATTCCTACCGGATGCTGCC
GGATTTCGGCGTTAACCAGTTCGAAAAGGTGCGCGTCAACGACATTATGGAAGTGCGCGAAACCGCAAGCCATATGGTCG
ATGCCATTGAAGGCCGGGCGCGCGCTTTCGTGCAGGTGCAAAATGGCTGCGACCACCGCTGTACTTTCTGCATCATTCCC
TATGGGCGCGGCAATTCGCGTTCCGTGCCGATGGGCGCAGTCGTCGATCAGGTGAAGCGGCTTGTCGGCAACGGCTATGC
CGAAGTGGTGCTGACCGGCGTGGACATGACATCCTACGGCCCCGACCTTCCCAGCAATCTTCGCCTGGGCAAGCTGGTAA
AAACCGTGCTGGCGCAAGTGCCGGATTTGCAGCGCCTGCGTCTTTCCTCCATCGATTCCATCGAGGCCGATGAGGATCTG
ATGGAAGCGATTGCCAGTGAAAAGCGCCTGATGCCACATCTGCACCTGTCGCTACAGGCTGGCGACGACATGATCCTGAA
GCGCATGAAGCGCCGCCATCTGCGCGACGATTCCATTCGCTTTTGCCAAACAGCGCGCGCTCTTCGCCCTGATATCGTGT
TCGGCGCGGATATCATCGCCGGTTTCCCGACCGAGACCGAGGAAATGTTCCAGAACTCGCTGAAGATTGTCGAGGAATGC
GGCCTTACCCATCTGCATGTCTTCCCCTATAGCCCGCGCGAGGGAACACCCGCAGCACGGATGCCGCAGGTACGGCGCGA
AATCGTCAAGGAACGCGCAGCCCGCCTGCGCGCCGAAGGCGACCGCGCCTATGAAAAGCACCTCAACGCGCTTCACGGCA
CACGCCAGCGCCTGCTGGTCGAGAAAGAAGGTGTTGCCCGCACGGAGGGCTTCACGCTGGCCGCTGTGGATCAGGGCAAT
GCTGGCGAAATTATCGAACGAATTGTGACGGGACATGACGGTGAAAAACTCCTCACACGTCAGGCAGAGCCGCAAGCGGC
TTAA

Upstream 100 bases:

>100_bases
AATGGGAATTCTCCGGCACCTTCGATCCTGCAACCGGCGAATGGAGCCGCGACACGCAGGGTTTGCAGGGTTCCGGCAAC
GCCGACAGGGGGGCTGCCTG

Downstream 100 bases:

>100_bases
AGCTTAAGGGCATCAGATTTCATGGCAATGGGTTTCATCAAGAAAATGTTCTCCTTCGGCAAGAAGGAGGTCGAAGAAAA
GCCGGCTGAACAACCGGCAC

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSVEIVTFGCRLNTYESEVMRREADAAGLGTLKDGAIIFNTCAVTAEAVRQARQAIRKARRENPDARIIVTGCAAQTEAD
NFAAMGEVDLVLGNEEKLKSNSYRMLPDFGVNQFEKVRVNDIMEVRETASHMVDAIEGRARAFVQVQNGCDHRCTFCIIP
YGRGNSRSVPMGAVVDQVKRLVGNGYAEVVLTGVDMTSYGPDLPSNLRLGKLVKTVLAQVPDLQRLRLSSIDSIEADEDL
MEAIASEKRLMPHLHLSLQAGDDMILKRMKRRHLRDDSIRFCQTARALRPDIVFGADIIAGFPTETEEMFQNSLKIVEEC
GLTHLHVFPYSPREGTPAARMPQVRREIVKERAARLRAEGDRAYEKHLNALHGTRQRLLVEKEGVARTEGFTLAAVDQGN
AGEIIERIVTGHDGEKLLTRQAEPQAA

Sequences:

>Translated_427_residues
MSVEIVTFGCRLNTYESEVMRREADAAGLGTLKDGAIIFNTCAVTAEAVRQARQAIRKARRENPDARIIVTGCAAQTEAD
NFAAMGEVDLVLGNEEKLKSNSYRMLPDFGVNQFEKVRVNDIMEVRETASHMVDAIEGRARAFVQVQNGCDHRCTFCIIP
YGRGNSRSVPMGAVVDQVKRLVGNGYAEVVLTGVDMTSYGPDLPSNLRLGKLVKTVLAQVPDLQRLRLSSIDSIEADEDL
MEAIASEKRLMPHLHLSLQAGDDMILKRMKRRHLRDDSIRFCQTARALRPDIVFGADIIAGFPTETEEMFQNSLKIVEEC
GLTHLHVFPYSPREGTPAARMPQVRREIVKERAARLRAEGDRAYEKHLNALHGTRQRLLVEKEGVARTEGFTLAAVDQGN
AGEIIERIVTGHDGEKLLTRQAEPQAA
>Mature_426_residues
SVEIVTFGCRLNTYESEVMRREADAAGLGTLKDGAIIFNTCAVTAEAVRQARQAIRKARRENPDARIIVTGCAAQTEADN
FAAMGEVDLVLGNEEKLKSNSYRMLPDFGVNQFEKVRVNDIMEVRETASHMVDAIEGRARAFVQVQNGCDHRCTFCIIPY
GRGNSRSVPMGAVVDQVKRLVGNGYAEVVLTGVDMTSYGPDLPSNLRLGKLVKTVLAQVPDLQRLRLSSIDSIEADEDLM
EAIASEKRLMPHLHLSLQAGDDMILKRMKRRHLRDDSIRFCQTARALRPDIVFGADIIAGFPTETEEMFQNSLKIVEECG
LTHLHVFPYSPREGTPAARMPQVRREIVKERAARLRAEGDRAYEKHLNALHGTRQRLLVEKEGVARTEGFTLAAVDQGNA
GEIIERIVTGHDGEKLLTRQAEPQAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=409, Percent_Identity=29.8288508557457, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI28872784, Length=444, Percent_Identity=24.7747747747748, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI28872782, Length=444, Percent_Identity=24.7747747747748, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1786882, Length=413, Percent_Identity=28.5714285714286, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787057, Length=366, Percent_Identity=31.4207650273224, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553146, Length=436, Percent_Identity=29.3577981651376, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71996771, Length=345, Percent_Identity=27.536231884058, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21356207, Length=378, Percent_Identity=26.7195767195767, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19922432, Length=377, Percent_Identity=27.0557029177719, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47408; Mature: 47277

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEIVTFGCRLNTYESEVMRREADAAGLGTLKDGAIIFNTCAVTAEAVRQARQAIRKAR
CCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
RENPDARIIVTGCAAQTEADNFAAMGEVDLVLGNEEKLKSNSYRMLPDFGVNQFEKVRVN
HCCCCCEEEEEECCCCCCCCCEEECCCEEEEECCHHHHCCCCCEECCCCCCCHHHHHHHH
DIMEVRETASHMVDAIEGRARAFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQVKR
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
LVGNGYAEVVLTGVDMTSYGPDLPSNLRLGKLVKTVLAQVPDLQRLRLSSIDSIEADEDL
HHCCCEEEEEEEECCHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHH
MEAIASEKRLMPHLHLSLQAGDDMILKRMKRRHLRDDSIRFCQTARALRPDIVFGADIIA
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEECCHHHC
GFPTETEEMFQNSLKIVEECGLTHLHVFPYSPREGTPAARMPQVRREIVKERAARLRAEG
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHHCCC
DRAYEKHLNALHGTRQRLLVEKEGVARTEGFTLAAVDQGNAGEIIERIVTGHDGEKLLTR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHC
QAEPQAA
CCCCCCC
>Mature Secondary Structure 
SVEIVTFGCRLNTYESEVMRREADAAGLGTLKDGAIIFNTCAVTAEAVRQARQAIRKAR
CEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
RENPDARIIVTGCAAQTEADNFAAMGEVDLVLGNEEKLKSNSYRMLPDFGVNQFEKVRVN
HCCCCCEEEEEECCCCCCCCCEEECCCEEEEECCHHHHCCCCCEECCCCCCCHHHHHHHH
DIMEVRETASHMVDAIEGRARAFVQVQNGCDHRCTFCIIPYGRGNSRSVPMGAVVDQVKR
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
LVGNGYAEVVLTGVDMTSYGPDLPSNLRLGKLVKTVLAQVPDLQRLRLSSIDSIEADEDL
HHCCCEEEEEEEECCHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHH
MEAIASEKRLMPHLHLSLQAGDDMILKRMKRRHLRDDSIRFCQTARALRPDIVFGADIIA
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEECCHHHC
GFPTETEEMFQNSLKIVEECGLTHLHVFPYSPREGTPAARMPQVRREIVKERAARLRAEG
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHHCCC
DRAYEKHLNALHGTRQRLLVEKEGVARTEGFTLAAVDQGNAGEIIERIVTGHDGEKLLTR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHC
QAEPQAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]