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The map label for this gene is glcB [H]

Identifier: 225853113

GI number: 225853113

Start: 1616942

End: 1619128

Strand: Direct

Name: glcB [H]

Synonym: BMEA_A1703

Alternate gene names: 225853113

Gene position: 1616942-1619128 (Clockwise)

Preceding gene: 225853112

Following gene: 225853114

Centisome position: 76.07

GC content: 58.48

Gene sequence:

>2187_bases
ATGGGTAGCGCAGAAAAACGTAACTATGTCGAGATTGAAGGCTTGGCTGTTGCCCCTGAGCTTGTGGAATTTCTGGCCAA
AGAAGCCGCGCCCGGCACAGGCGTGGAGCCGGAGAAATTCTGGAAGGGCTTTGCCGCCATCATTCGCGATCTCGCACCAA
AGAACCGCGCCCTGCTCGCCAAGCGTGACGAGCTTCAGGCCAGGATCGACGCCTGGTACAAGGAAAACCGCGACAAGGGC
TACAGCCAGGCCGATTACCAGCAGTTTCTGAAAGATATCGGCTATCTCCTGCCGGAAGGTGGAGCGTTTTCGGTTTCGAC
CACCAATGTCGATCCTGAAATCACCCATATTGCCGGTCCGCAGCTTGTCGTCCCGGTCATGAATGCGCGCTATGCACTCA
ACGCCGCCAATGCGCGCTGGGGCTCGCTCTATGATGCGCTTTATGGCACCGACGCGATTTCCGAGGCCGATGGCGCGGAA
AAGGGCAAGGGCTACAATCCGAAGCGCGGTGAAAAGGTTATTGCGTGGGCGAAGAATTTCCTCGATGAAAGCGCACCGCT
CAGCACGGGCAAATGGGCCGATGTTGCCGGTCTCGCCGTGAACGACGGCAAGCTTGAAATCAGGCTGACCGATGGTTCGG
CAACCACCTTAAAGGACGAAAGCCAGTTCAAGGGCTATAATGGCGATGCCGCCAGCCCAACGAATGTGCTTCTTGCCAAG
CACAATATGCATGTTGATATCGTCATCAATGCAGATCACCCGATCGGCAAGACCGATCCGGCGCATATTGCCGATGTGGT
TCTGGAATCGGCCATCAGCACGATCCAGGATTGTGAGGACTCCATTGCCGCCGTCGATGCCGAAGACAAGGTTGCCGTCT
ATCGCAACTGGCTCGGCCTGATGAATGGCAAGCTGGAAGACACGTTCGAGAAGAACGGCAAGCAGATGACGCGCCGCCTC
AATGGCGACCGCACCTACACGGCGCCGGACGGTTCCACGCTGACGCTCAAGGGCCGTTCCTTGATGCTGGTGCGCAATGT
CGGCCACCTGATGACCAACCCGGCCATTCTGGACGCCGAAGGCAATGAAGTGCCGGAAGGCATCATGGATGCAGCCTTCA
CCAGCCTGATTGCGCTGCATGATATCGGCCCCAATGGCCGCCACATGAATTCGCGCGAAGGCTCGGTCTATATCGTCAAG
CCAAAAATGCATGGGCCGGAAGAAGTGGCATTCGCAAATGAAATCTTCACCCGGACCGAAGAAATGCTCGGCATGAAGCC
GAATACGCTCAAAATCGGCATCATGGACGAAGAACGCCGCACGACCGTCAATCTCAAGGAGGCAATCCGCGCCGCCAAGG
ATCGCGTCGTCTTCATCAATACCGGCTTCCTCGACCGCACGGGCGACGAGATCCACACCTCCATGGAAGCAGGCCCGATG
ATCCGCAAGGGCGACATGAAGCAGGCTGCGTGGATCGGCGCCTATGAACAATGGAATGTCGATATCGGTCTGGAATGCGG
GCTTTCCGGCCATGCGCAGATCGGCAAGGGCATGTGGGCCATGCCCGACATGATGGCGGCAATGCTGGAGCAGAAGATCG
CGCATCCGAAGGCCGGTGCGAACACCGCCTGGGTGCCGTCGCCGACCGCCGCCACCTTGCACGCTACCCATTACCACAAG
ATCGATGTAGCCGCCGTTCAGGAAAAGCTGAAAAGCCGTCCCCGCGCCAAGCTGGACGATATCCTGTCGGTGCCGGTTGC
GGTGCGTCCGAACTGGACGCCGGACGATATCCAGCACGAAATCGACAACAATGCACAAGGCATTCTCGGCTATGTCGTGC
GCTGGATCGATCAGGGTGTCGGCTGCTCCAAGGTGCCGGACATCAACAATGTCGGCCTGATGGAAGACCGCGCGACGCTG
CGCATTTCCGCGCAGCACATCGCCAACTGGCTCTATCATGGCGTCGTGTCAGAGGCACAGGTGATGGAAACCATGAAGCG
CATGGCAGCCATCGTCGACAAGCAGAACGAAGGCGACCCGCTTTATCGCCCGATGGCCGCTGATTTTGACAAGTCGATTG
CCTTCCAGGCGGCTTGCGATCTGGTCTTCAAGGGCCGCGAACAGCCGAACGGCTACACCGAGCCGGTCCTGCATCGCCGC
CGGCTCGAACTGAAACAGGCTTCCTGA

Upstream 100 bases:

>100_bases
CCGATTGACGAAAACGCGCCAAGGCGGTTCAAAGGCAGTATGATGACCGGCATTTAAAAATGCTGGCAATAGATTTGTAT
ATTTCAATGGAGGCGAAGCC

Downstream 100 bases:

>100_bases
GGTTGCCCTCCCCCTCATCCTGAGGAGGTGAACTGAGCGCAGCGAAGGAAACCGTCTCGAAGGGCTGAGGGGGCATGAGC
GACGCGGCGGCAATCCTCAT

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MGSAEKRNYVEIEGLAVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLAPKNRALLAKRDELQARIDAWYKENRDKG
YSQADYQQFLKDIGYLLPEGGAFSVSTTNVDPEITHIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAISEADGAE
KGKGYNPKRGEKVIAWAKNFLDESAPLSTGKWADVAGLAVNDGKLEIRLTDGSATTLKDESQFKGYNGDAASPTNVLLAK
HNMHVDIVINADHPIGKTDPAHIADVVLESAISTIQDCEDSIAAVDAEDKVAVYRNWLGLMNGKLEDTFEKNGKQMTRRL
NGDRTYTAPDGSTLTLKGRSLMLVRNVGHLMTNPAILDAEGNEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVK
PKMHGPEEVAFANEIFTRTEEMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKDRVVFINTGFLDRTGDEIHTSMEAGPM
IRKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDMMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHK
IDVAAVQEKLKSRPRAKLDDILSVPVAVRPNWTPDDIQHEIDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATL
RISAQHIANWLYHGVVSEAQVMETMKRMAAIVDKQNEGDPLYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRR
RLELKQAS

Sequences:

>Translated_728_residues
MGSAEKRNYVEIEGLAVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLAPKNRALLAKRDELQARIDAWYKENRDKG
YSQADYQQFLKDIGYLLPEGGAFSVSTTNVDPEITHIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAISEADGAE
KGKGYNPKRGEKVIAWAKNFLDESAPLSTGKWADVAGLAVNDGKLEIRLTDGSATTLKDESQFKGYNGDAASPTNVLLAK
HNMHVDIVINADHPIGKTDPAHIADVVLESAISTIQDCEDSIAAVDAEDKVAVYRNWLGLMNGKLEDTFEKNGKQMTRRL
NGDRTYTAPDGSTLTLKGRSLMLVRNVGHLMTNPAILDAEGNEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVK
PKMHGPEEVAFANEIFTRTEEMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKDRVVFINTGFLDRTGDEIHTSMEAGPM
IRKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDMMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHK
IDVAAVQEKLKSRPRAKLDDILSVPVAVRPNWTPDDIQHEIDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATL
RISAQHIANWLYHGVVSEAQVMETMKRMAAIVDKQNEGDPLYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRR
RLELKQAS
>Mature_727_residues
GSAEKRNYVEIEGLAVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLAPKNRALLAKRDELQARIDAWYKENRDKGY
SQADYQQFLKDIGYLLPEGGAFSVSTTNVDPEITHIAGPQLVVPVMNARYALNAANARWGSLYDALYGTDAISEADGAEK
GKGYNPKRGEKVIAWAKNFLDESAPLSTGKWADVAGLAVNDGKLEIRLTDGSATTLKDESQFKGYNGDAASPTNVLLAKH
NMHVDIVINADHPIGKTDPAHIADVVLESAISTIQDCEDSIAAVDAEDKVAVYRNWLGLMNGKLEDTFEKNGKQMTRRLN
GDRTYTAPDGSTLTLKGRSLMLVRNVGHLMTNPAILDAEGNEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVKP
KMHGPEEVAFANEIFTRTEEMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKDRVVFINTGFLDRTGDEIHTSMEAGPMI
RKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDMMAAMLEQKIAHPKAGANTAWVPSPTAATLHATHYHKI
DVAAVQEKLKSRPRAKLDDILSVPVAVRPNWTPDDIQHEIDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLR
ISAQHIANWLYHGVVSEAQVMETMKRMAAIVDKQNEGDPLYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRRR
LELKQAS

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=718, Percent_Identity=59.7493036211699, Blast_Score=899, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=324, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 79987; Mature: 79856

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSAEKRNYVEIEGLAVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLAPKNRALLA
CCCCCCCCEEEEECEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHH
KRDELQARIDAWYKENRDKGYSQADYQQFLKDIGYLLPEGGAFSVSTTNVDPEITHIAGP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCC
QLVVPVMNARYALNAANARWGSLYDALYGTDAISEADGAEKGKGYNPKRGEKVIAWAKNF
EEEEEECCCCEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
LDESAPLSTGKWADVAGLAVNDGKLEIRLTDGSATTLKDESQFKGYNGDAASPTNVLLAK
HCCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCEECCHHHCCCCCCCCCCCCEEEEEE
HNMHVDIVINADHPIGKTDPAHIADVVLESAISTIQDCEDSIAAVDAEDKVAVYRNWLGL
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
MNGKLEDTFEKNGKQMTRRLNGDRTYTAPDGSTLTLKGRSLMLVRNVGHLMTNPAILDAE
HCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEEHHHHHHCCCEEEECC
GNEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVKPKMHGPEEVAFANEIFTRTE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
EMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKDRVVFINTGFLDRTGDEIHTSMEAGPM
HHHCCCCCEEEEEEECCCCCCEECHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCC
IRKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDMMAAMLEQKIAHPKAGA
EECCCCCHHHHCCCHHHCCCEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
NTAWVPSPTAATLHATHYHKIDVAAVQEKLKSRPRAKLDDILSVPVAVRPNWTPDDIQHE
CCCCCCCCCCEEEEECCEEEHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHH
IDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISAQHIANWLYHGVVSEAQ
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
VMETMKRMAAIVDKQNEGDPLYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRR
HHHHHHHHHHHHCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RLELKQAS
HHHHCCCC
>Mature Secondary Structure 
GSAEKRNYVEIEGLAVAPELVEFLAKEAAPGTGVEPEKFWKGFAAIIRDLAPKNRALLA
CCCCCCCEEEEECEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHH
KRDELQARIDAWYKENRDKGYSQADYQQFLKDIGYLLPEGGAFSVSTTNVDPEITHIAGP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCC
QLVVPVMNARYALNAANARWGSLYDALYGTDAISEADGAEKGKGYNPKRGEKVIAWAKNF
EEEEEECCCCEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
LDESAPLSTGKWADVAGLAVNDGKLEIRLTDGSATTLKDESQFKGYNGDAASPTNVLLAK
HCCCCCCCCCCCCCEEEEEEECCEEEEEEECCCCCEECCHHHCCCCCCCCCCCCEEEEEE
HNMHVDIVINADHPIGKTDPAHIADVVLESAISTIQDCEDSIAAVDAEDKVAVYRNWLGL
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
MNGKLEDTFEKNGKQMTRRLNGDRTYTAPDGSTLTLKGRSLMLVRNVGHLMTNPAILDAE
HCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEEHHHHHHCCCEEEECC
GNEVPEGIMDAAFTSLIALHDIGPNGRHMNSREGSVYIVKPKMHGPEEVAFANEIFTRTE
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
EMLGMKPNTLKIGIMDEERRTTVNLKEAIRAAKDRVVFINTGFLDRTGDEIHTSMEAGPM
HHHCCCCCEEEEEEECCCCCCEECHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHCCCC
IRKGDMKQAAWIGAYEQWNVDIGLECGLSGHAQIGKGMWAMPDMMAAMLEQKIAHPKAGA
EECCCCCHHHHCCCHHHCCCEEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
NTAWVPSPTAATLHATHYHKIDVAAVQEKLKSRPRAKLDDILSVPVAVRPNWTPDDIQHE
CCCCCCCCCCEEEEECCEEEHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHH
IDNNAQGILGYVVRWIDQGVGCSKVPDINNVGLMEDRATLRISAQHIANWLYHGVVSEAQ
HCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
VMETMKRMAAIVDKQNEGDPLYRPMAADFDKSIAFQAACDLVFKGREQPNGYTEPVLHRR
HHHHHHHHHHHHCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RLELKQAS
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA