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The map label for this gene is cobI [H]

Identifier: 225852780

GI number: 225852780

Start: 1268942

End: 1269676

Strand: Direct

Name: cobI [H]

Synonym: BMEA_A1335

Alternate gene names: 225852780

Gene position: 1268942-1269676 (Clockwise)

Preceding gene: 225852779

Following gene: 225852781

Centisome position: 59.7

GC content: 58.78

Gene sequence:

>735_bases
ATGGCGGCGAAAGGCAGATTGTTCGGCCTGGGCGTCGGCCCCGGCGACCCCGAACTGATTACTCTGAAAGCCCTGCGGCT
CCTCAAATCCGCACCGGTCGTGGCCTATCATGCGGCGCGGGGCAAGAAGGGTAATGCGTTCACTATTGTCGAGGATTATC
TTTCGCCGGAACAGGTGCTGCTGCCGCTCATCTATCCTGTTACCACCGAAAAACTGCCGGACCATATGGATTATGAGCAG
GTCGTGAAGGATTTCTACGGCGAAATCACCACGACCATCGCCAGCCATCTGGATCAGGGGCAGGATGTGGCGGTGATCGC
AGAGGGCGACCCGTTCTTCTACGGCTCCTTCATGTATATCCATGACAGGCTTGCGGAAAAATACGAAACCCATGTGGTGC
CGGGCGTCTGTTCCGTTCTGGGGGCTTCGGCGGTGCTTGGTGCGCCGCTTGTCTATCGCAACCAGACCCTGTCCGTCCTT
TCCGGCGTCATGAGTGCGAACGAGTTGCGTCAGCGCCTTGCACAGACGGAAGCGGCGGCAATCATGAAGCTTGGCAAAAA
TCTCGACAAGGTGCGGGCCGTGCTGGGCGATCTCGGCCTCATGGGCCGCGCGCTTTATGTCGAGCGCGCCACCATGGCCA
ATCAACGTATCGTGCCGTTGGCCGAGGTTAATGGCAGCGATTGCCCCTATTTCTCGCTCATTCTGGTGCCCGGCGAAAAA
TGGAACGGCGCATGA

Upstream 100 bases:

>100_bases
CCAACAGCCGCGGCGTGCCTTACGTGATCGTGCGCGGGCGACGCGGCGGCAGCGCCATGACGGCAGCCGCGGTCAACGCG
CTTGCTTCGGAGCGTGAATA

Downstream 100 bases:

>100_bases
TCCCCGCCATTCTCGTTCTTGCAGAAGCAGCACTCCCGACCACGCGCCAGATCGCGGCCGCATTGGAACGCGCTGAAGTT
CTGGGCCTGCACGACCGCGT

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAAKGRLFGLGVGPGDPELITLKALRLLKSAPVVAYHAARGKKGNAFTIVEDYLSPEQVLLPLIYPVTTEKLPDHMDYEQ
VVKDFYGEITTTIASHLDQGQDVAVIAEGDPFFYGSFMYIHDRLAEKYETHVVPGVCSVLGASAVLGAPLVYRNQTLSVL
SGVMSANELRQRLAQTEAAAIMKLGKNLDKVRAVLGDLGLMGRALYVERATMANQRIVPLAEVNGSDCPYFSLILVPGEK
WNGA

Sequences:

>Translated_244_residues
MAAKGRLFGLGVGPGDPELITLKALRLLKSAPVVAYHAARGKKGNAFTIVEDYLSPEQVLLPLIYPVTTEKLPDHMDYEQ
VVKDFYGEITTTIASHLDQGQDVAVIAEGDPFFYGSFMYIHDRLAEKYETHVVPGVCSVLGASAVLGAPLVYRNQTLSVL
SGVMSANELRQRLAQTEAAAIMKLGKNLDKVRAVLGDLGLMGRALYVERATMANQRIVPLAEVNGSDCPYFSLILVPGEK
WNGA
>Mature_243_residues
AAKGRLFGLGVGPGDPELITLKALRLLKSAPVVAYHAARGKKGNAFTIVEDYLSPEQVLLPLIYPVTTEKLPDHMDYEQV
VKDFYGEITTTIASHLDQGQDVAVIAEGDPFFYGSFMYIHDRLAEKYETHVVPGVCSVLGASAVLGAPLVYRNQTLSVLS
GVMSANELRQRLAQTEAAAIMKLGKNLDKVRAVLGDLGLMGRALYVERATMANQRIVPLAEVNGSDCPYFSLILVPGEKW
NGA

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26450; Mature: 26319

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKGRLFGLGVGPGDPELITLKALRLLKSAPVVAYHAARGKKGNAFTIVEDYLSPEQVL
CCCCCCEEEEECCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCCCEEEEEHHHCCHHHHH
LPLIYPVTTEKLPDHMDYEQVVKDFYGEITTTIASHLDQGQDVAVIAEGDPFFYGSFMYI
HHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEHHHHH
HDRLAEKYETHVVPGVCSVLGASAVLGAPLVYRNQTLSVLSGVMSANELRQRLAQTEAAA
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IMKLGKNLDKVRAVLGDLGLMGRALYVERATMANQRIVPLAEVNGSDCPYFSLILVPGEK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEECCC
WNGA
CCCC
>Mature Secondary Structure 
AAKGRLFGLGVGPGDPELITLKALRLLKSAPVVAYHAARGKKGNAFTIVEDYLSPEQVL
CCCCCEEEEECCCCCCCEEHHHHHHHHHHCCEEEEECCCCCCCCEEEEEHHHCCHHHHH
LPLIYPVTTEKLPDHMDYEQVVKDFYGEITTTIASHLDQGQDVAVIAEGDPFFYGSFMYI
HHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEHHHHH
HDRLAEKYETHVVPGVCSVLGASAVLGAPLVYRNQTLSVLSGVMSANELRQRLAQTEAAA
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
IMKLGKNLDKVRAVLGDLGLMGRALYVERATMANQRIVPLAEVNGSDCPYFSLILVPGEK
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEEEECCC
WNGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]