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The map label for this gene is wrbA [H]

Identifier: 225852552

GI number: 225852552

Start: 1037413

End: 1038012

Strand: Direct

Name: wrbA [H]

Synonym: BMEA_A1089

Alternate gene names: 225852552

Gene position: 1037413-1038012 (Clockwise)

Preceding gene: 225852547

Following gene: 225852554

Centisome position: 48.8

GC content: 59.17

Gene sequence:

>600_bases
ATGGTAAAGATGCTGGTGCTGTATTATTCGGCCTATGGCTACATGGAACAGATGGCGAAGGCTGCTGCTGAAGGGGCGCG
CGAAGGCGGCGCAGAGGTTACGCTGAAGCGTGTTCCCGAACTGGTGCCAGAGGAAGTGGCGAAAGCTTCGCATTACAAGA
TCGATCAGGAAGCGCCGATTGCCACGCCGGGCGAGCTTGCAGATTATGATGCCATCATTATCGGCACCGCAACGCGCTAT
GGCATGATGGCTTCACAGATGAAGAATTTCCTCGACCAGACCGGCGGGCTGTGGGCCAAAGGGGCACTGATAAACAAGGT
TGGCTCGGTCATGGTTTCAACGGCCACCCAACATGGCGGCGCTGAACTGGCGCTGATTTCCACCCAATGGCAGATGCAGC
ACCACGGCATGATTATCGTGCCGCTTTCCTACGCCTGTCGGGAGCAGATGGGGAATGATGTGGTGCGCGGCGGGGCGCCT
TACGGCATGACAACCACCGCCGATGGCGACGGCTCGCGCCAGCCTTCCGCACAGGAACTGGATGGCGCCCGTTTCCAGGG
CAGGCGGGTTGCGGAAATTACCGCGAAACTGCATGGCTGA

Upstream 100 bases:

>100_bases
TTATCGTTCTTCGTTTTGCCGCCTTTCCAAAGCTTCGCGCTCCCTTAATTAAGTTTCTACGAGGGAGAGGCCTCGCCATT
ACGATTAACGGAGATGTCAG

Downstream 100 bases:

>100_bases
CCAAACTGGGCAGTTGCGAAGCCGCCACTTGATTGGCGGCTTTTTCGCTTAATTCCACAAGCTTATGTGTGAATGCCAGC
AGTTGCCACCGGCAAGCTTT

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPIATPGELADYDAIIIGTATRY
GMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYACREQMGNDVVRGGAP
YGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG

Sequences:

>Translated_199_residues
MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPIATPGELADYDAIIIGTATRY
GMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYACREQMGNDVVRGGAP
YGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG
>Mature_199_residues
MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPIATPGELADYDAIIIGTATRY
GMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYACREQMGNDVVRGGAP
YGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=200, Percent_Identity=57.5, Blast_Score=215, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=40.2010050251256, Blast_Score=138, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6319849, Length=200, Percent_Identity=38, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319526, Length=201, Percent_Identity=31.3432835820896, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 21355; Mature: 21355

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPI
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
ATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGG
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCC
AELALISTQWQMQHHGMIIVPLSYACREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQEL
CEEEEEECEEEHHHCCEEEEECCHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHH
DGARFQGRRVAEITAKLHG
CCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPI
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
ATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGG
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCC
AELALISTQWQMQHHGMIIVPLSYACREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQEL
CEEEEEECEEEHHHCCEEEEECCHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHH
DGARFQGRRVAEITAKLHG
CCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA