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The map label for this gene is sufC [H]

Identifier: 225852443

GI number: 225852443

Start: 926933

End: 927688

Strand: Direct

Name: sufC [H]

Synonym: BMEA_A0970

Alternate gene names: 225852443

Gene position: 926933-927688 (Clockwise)

Preceding gene: 225852442

Following gene: 225852444

Centisome position: 43.61

GC content: 55.82

Gene sequence:

>756_bases
ATGCTTGAGATCAAGAACCTCCATGCAAAGATCGCCGATACGGATACCGAGATCATCCGCGGCCTGAACCTCACCGTGAA
CAAGGGTGAAGTGGCGGCGATCATGGGTCCGAACGGTTCGGGCAAGTCCACGCTTTCCTATATTCTCGCTGGCCGTGATG
ATTATGAGGTCACCGAAGGTGACATTCTCTATAATGGCGAGTCGATCCTCGAACTCGATCCGGCTGAACGCGCTGCCAAG
GGCATCTTCCTTGCGTTCCAGTATCCGATGGAAATTCCGGGCGTTGCCACGATGGAATTCCTGAAGGTTGCGATGAACAG
CCAGCGCAAGGCGCGCGGCGAGCCGGAACTGAATATCCCCGAATTCATCAAGCGGGTGAAGGACGCCGCCGGCGGCCTCA
ACATCGATATGAATATGCTGAAGCGCCCGCTTAACGTTGGCTTCTCAGGCGGTGAAAAGAAGCGCGCTGAAATTCTTCAA
ATGCAGCTTCTGGAGCCAAGCCTTTGCGTTCTCGACGAAACCGACTCCGGCCTCGATATCGATGCGCTGAAGATCGTTTC
GGAAGGTGTCAACGCATTGCGTTCGCCTGATCGCGCCGTGATCGTCATCACGCACTATCAGCGCCTGCTTGAACATATCG
TCCCGGACAGCGTGCATGTGCTCTACAAGGGGCAGGTCATCAAGTCCGGCGACAAGAGCCTCGCGCTGCATCTGGAAGAA
AATGGTTATGCCGACGTAATCGGCGAAGCCGCCTGA

Upstream 100 bases:

>100_bases
ATCGGCATCTCGCTTGAGGGCAGCGTCGGTTAAAAGCCGTATTCACCGTTCCGATTTTTCTGGCCAGCCTTTTCCTGGCA
TTAGAGCAAGGTTTAAATTT

Downstream 100 bases:

>100_bases
GGAGGGTTGGATCATGAATATCCAGGCCACTTCGGCACCCAAGCCGCGCACCCCGGCTGAAAGCGTGCTGATCGACAGTT
TTGCCGAGCGCATGGGCGAT

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLEIKNLHAKIADTDTEIIRGLNLTVNKGEVAAIMGPNGSGKSTLSYILAGRDDYEVTEGDILYNGESILELDPAERAAK
GIFLAFQYPMEIPGVATMEFLKVAMNSQRKARGEPELNIPEFIKRVKDAAGGLNIDMNMLKRPLNVGFSGGEKKRAEILQ
MQLLEPSLCVLDETDSGLDIDALKIVSEGVNALRSPDRAVIVITHYQRLLEHIVPDSVHVLYKGQVIKSGDKSLALHLEE
NGYADVIGEAA

Sequences:

>Translated_251_residues
MLEIKNLHAKIADTDTEIIRGLNLTVNKGEVAAIMGPNGSGKSTLSYILAGRDDYEVTEGDILYNGESILELDPAERAAK
GIFLAFQYPMEIPGVATMEFLKVAMNSQRKARGEPELNIPEFIKRVKDAAGGLNIDMNMLKRPLNVGFSGGEKKRAEILQ
MQLLEPSLCVLDETDSGLDIDALKIVSEGVNALRSPDRAVIVITHYQRLLEHIVPDSVHVLYKGQVIKSGDKSLALHLEE
NGYADVIGEAA
>Mature_251_residues
MLEIKNLHAKIADTDTEIIRGLNLTVNKGEVAAIMGPNGSGKSTLSYILAGRDDYEVTEGDILYNGESILELDPAERAAK
GIFLAFQYPMEIPGVATMEFLKVAMNSQRKARGEPELNIPEFIKRVKDAAGGLNIDMNMLKRPLNVGFSGGEKKRAEILQ
MQLLEPSLCVLDETDSGLDIDALKIVSEGVNALRSPDRAVIVITHYQRLLEHIVPDSVHVLYKGQVIKSGDKSLALHLEE
NGYADVIGEAA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=217, Percent_Identity=26.7281105990783, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI42741659, Length=211, Percent_Identity=27.9620853080569, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=56.1475409836066, Blast_Score=283, Evalue=6e-78,
Organism=Escherichia coli, GI87082267, Length=171, Percent_Identity=34.5029239766082, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787759, Length=264, Percent_Identity=26.8939393939394, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789891, Length=222, Percent_Identity=29.2792792792793, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787500, Length=240, Percent_Identity=27.5, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790525, Length=219, Percent_Identity=29.6803652968037, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=192, Percent_Identity=26.5625, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788897, Length=215, Percent_Identity=29.7674418604651, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=231, Percent_Identity=25.1082251082251, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789963, Length=244, Percent_Identity=26.2295081967213, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787758, Length=241, Percent_Identity=25.7261410788382, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI48994883, Length=244, Percent_Identity=29.0983606557377, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790467, Length=220, Percent_Identity=29.0909090909091, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=24.3119266055046, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1786703, Length=213, Percent_Identity=28.169014084507, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789672, Length=216, Percent_Identity=24.537037037037, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984940, Length=227, Percent_Identity=29.5154185022026, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=233, Percent_Identity=29.1845493562232, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193209708, Length=235, Percent_Identity=28.5106382978723, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=190, Percent_Identity=29.4736842105263, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=222, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=226, Percent_Identity=28.3185840707965, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=230, Percent_Identity=26.5217391304348, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=221, Percent_Identity=27.6018099547511, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI85726357, Length=234, Percent_Identity=25.6410256410256, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27398; Mature: 27398

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEIKNLHAKIADTDTEIIRGLNLTVNKGEVAAIMGPNGSGKSTLSYILAGRDDYEVTEG
CCCCCCCCEEECCCHHHHHCCCCEEEECCCEEEEECCCCCCCHHEEEEEECCCCCEECCC
DILYNGESILELDPAERAAKGIFLAFQYPMEIPGVATMEFLKVAMNSQRKARGEPELNIP
EEEECCCCEEEECCHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHH
EFIKRVKDAAGGLNIDMNMLKRPLNVGFSGGEKKRAEILQMQLLEPSLCVLDETDSGLDI
HHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVSEGVNALRSPDRAVIVITHYQRLLEHIVPDSVHVLYKGQVIKSGDKSLALHLEE
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCEEEEEECEEEECCCCEEEEEEEC
NGYADVIGEAA
CCCCCCCCCCC
>Mature Secondary Structure
MLEIKNLHAKIADTDTEIIRGLNLTVNKGEVAAIMGPNGSGKSTLSYILAGRDDYEVTEG
CCCCCCCCEEECCCHHHHHCCCCEEEECCCEEEEECCCCCCCHHEEEEEECCCCCEECCC
DILYNGESILELDPAERAAKGIFLAFQYPMEIPGVATMEFLKVAMNSQRKARGEPELNIP
EEEECCCCEEEECCHHHHHCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHH
EFIKRVKDAAGGLNIDMNMLKRPLNVGFSGGEKKRAEILQMQLLEPSLCVLDETDSGLDI
HHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCH
DALKIVSEGVNALRSPDRAVIVITHYQRLLEHIVPDSVHVLYKGQVIKSGDKSLALHLEE
HHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCEEEEEECEEEECCCCEEEEEEEC
NGYADVIGEAA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]