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The map label for this gene is amiC [H]

Identifier: 225852426

GI number: 225852426

Start: 908204

End: 909472

Strand: Direct

Name: amiC [H]

Synonym: BMEA_A0953

Alternate gene names: 225852426

Gene position: 908204-909472 (Clockwise)

Preceding gene: 225852425

Following gene: 225852427

Centisome position: 42.72

GC content: 56.9

Gene sequence:

>1269_bases
ATGGATTTACAAAGCCATTATAAAGTGGGAGCCAGCTTTCAGGCCATACGGGTTTTGTTCGTGCTTCTTGCATTGTTCTG
CCTGTCACTCGCTAATGTGCCTTCCACTTTTGCTGCCGATAGCCCGGCTCCGCCACTTTCGGCCCTCACATTTCGTATGG
CTGGCGATGATCTGCGCACGCGCGTCGTTGTCATGTTCGATCGGGAACCGAAGCTTTCAACACGGCTGTTTGGCAATCCG
CATCGTCTGGTGATCGATCTGCCGGAAACCCGTTTCGGCTTCGATGAAAAAAGCCTTGAGGCGAGGGGGCTTGTTTCGCA
CGTGCGTTATGGCCTGGCGGGGAAGGGGTGTTCGCGGCTGATTCTCACCTTGCGGGGGGCTTTCGATGTCGAAAACCTTC
GTGTTCTCAAAAATGAGAACGCCTCCGGCTATCGCTTGGTGGCGGATATTGTCGCAACCTCTGACAGGAAGTTCGCCGAA
AAGCTCAAGGAGCAGAAAGGTAAAACCGGCTCGACCGAGCGGGCCCGGCAACAGGTGGCTGGTTCAGCCCTGCCGGGGAA
TGGCAAGCCGCGACCCTTTACGGTGATGATCGATCCCGGCCATGGCGGCATAGACAGCGGTGCGGAAAGCCTGAGTGGAA
TCAAGGAAAAGAACCTGACGCTCGCCTTCGGCAAGGAGTTGCGTGACAGGCTCTCCCATGAACGGAACATCAAGGTTTTG
ATGACGCGCGAGGACGACACGTTCCTGCGCCTGGCTGAGCGGGTGCGTCTGGCGCGCCAGCATGAAGCAGACCTTTTTAT
CTCCATTCACGCCGATACCATCAACCAGCACGATATTCGCGGGGCGACCGTCTATACGATTTCCGACAAGGCGTCGGACG
CTGTTGCGCGCGCCATGGCGGAGCGTGAAAACAAGTCCGACAGTCTGGCCGGCGCGCTGCCGGAAGAACAGCCCGAAGTC
ACCGATATCCTGCTCGACCTCACGCGGCGCGAAACGCACACCTTCTCCTTAAGCTTTGCCGAAAAGGTGATTGGCGAATT
GCAGGGGCAGGTGAACCTCATTAATAATCCGCATCGCTTCGCCGGCTTTCAGGTTCTGCGGGCACCCGATGTTCCTTCCG
TGCTGATTGAGATTGGCTATCTTTCCAACCCGGAGGATGAAAAACTCATCAGCAACCCGGAATGGCGTAAAAAACTGGCA
GACAGGATCGCACTTGCGGTGAAGGCCTTTGCCGCGCGCAAGAGACCCTCAAATCTCAGCGGCGGATAG

Upstream 100 bases:

>100_bases
CGGTAGTTTTGTACGACGGATCAGGAGCCGCGCGAGGCAAGCGATCTCGGTATCGCGCCACAACCCACCTGTTCGATAAT
GTTTTCGATTGTGACGGTGT

Downstream 100 bases:

>100_bases
TTTTTCGCGGATAGTTTTTCAAAGTGCGGTTTTGCATTAGCATTCGATGGAATTAACATGCGCTCATAAGATGCAGGCTT
GCAACAGCCCCTCTTATTTT

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDLQSHYKVGASFQAIRVLFVLLALFCLSLANVPSTFAADSPAPPLSALTFRMAGDDLRTRVVVMFDREPKLSTRLFGNP
HRLVIDLPETRFGFDEKSLEARGLVSHVRYGLAGKGCSRLILTLRGAFDVENLRVLKNENASGYRLVADIVATSDRKFAE
KLKEQKGKTGSTERARQQVAGSALPGNGKPRPFTVMIDPGHGGIDSGAESLSGIKEKNLTLAFGKELRDRLSHERNIKVL
MTREDDTFLRLAERVRLARQHEADLFISIHADTINQHDIRGATVYTISDKASDAVARAMAERENKSDSLAGALPEEQPEV
TDILLDLTRRETHTFSLSFAEKVIGELQGQVNLINNPHRFAGFQVLRAPDVPSVLIEIGYLSNPEDEKLISNPEWRKKLA
DRIALAVKAFAARKRPSNLSGG

Sequences:

>Translated_422_residues
MDLQSHYKVGASFQAIRVLFVLLALFCLSLANVPSTFAADSPAPPLSALTFRMAGDDLRTRVVVMFDREPKLSTRLFGNP
HRLVIDLPETRFGFDEKSLEARGLVSHVRYGLAGKGCSRLILTLRGAFDVENLRVLKNENASGYRLVADIVATSDRKFAE
KLKEQKGKTGSTERARQQVAGSALPGNGKPRPFTVMIDPGHGGIDSGAESLSGIKEKNLTLAFGKELRDRLSHERNIKVL
MTREDDTFLRLAERVRLARQHEADLFISIHADTINQHDIRGATVYTISDKASDAVARAMAERENKSDSLAGALPEEQPEV
TDILLDLTRRETHTFSLSFAEKVIGELQGQVNLINNPHRFAGFQVLRAPDVPSVLIEIGYLSNPEDEKLISNPEWRKKLA
DRIALAVKAFAARKRPSNLSGG
>Mature_422_residues
MDLQSHYKVGASFQAIRVLFVLLALFCLSLANVPSTFAADSPAPPLSALTFRMAGDDLRTRVVVMFDREPKLSTRLFGNP
HRLVIDLPETRFGFDEKSLEARGLVSHVRYGLAGKGCSRLILTLRGAFDVENLRVLKNENASGYRLVADIVATSDRKFAE
KLKEQKGKTGSTERARQQVAGSALPGNGKPRPFTVMIDPGHGGIDSGAESLSGIKEKNLTLAFGKELRDRLSHERNIKVL
MTREDDTFLRLAERVRLARQHEADLFISIHADTINQHDIRGATVYTISDKASDAVARAMAERENKSDSLAGALPEEQPEV
TDILLDLTRRETHTFSLSFAEKVIGELQGQVNLINNPHRFAGFQVLRAPDVPSVLIEIGYLSNPEDEKLISNPEWRKKLA
DRIALAVKAFAARKRPSNLSGG

Specific function: Cell-wall hydrolase involved in septum cleavage during cell division [H]

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

Organism=Escherichia coli, GI87082163, Length=403, Percent_Identity=30.0248138957816, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788776, Length=233, Percent_Identity=37.3390557939914, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1790611, Length=224, Percent_Identity=33.0357142857143, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021731
- InterPro:   IPR002508
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01520 Amidase_3; PF11741 AMIN [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 46616; Mature: 46616

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLQSHYKVGASFQAIRVLFVLLALFCLSLANVPSTFAADSPAPPLSALTFRMAGDDLRT
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEECCCCCCE
RVVVMFDREPKLSTRLFGNPHRLVIDLPETRFGFDEKSLEARGLVSHVRYGLAGKGCSRL
EEEEEECCCCCCCHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
ILTLRGAFDVENLRVLKNENASGYRLVADIVATSDRKFAEKLKEQKGKTGSTERARQQVA
HHHHHCCCCCCHHHEEECCCCCCCEEHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHC
GSALPGNGKPRPFTVMIDPGHGGIDSGAESLSGIKEKNLTLAFGKELRDRLSHERNIKVL
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHCHHHCCEEEEHHHHHHHHHCCCCCEEEE
MTREDDTFLRLAERVRLARQHEADLFISIHADTINQHDIRGATVYTISDKASDAVARAMA
EECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHH
ERENKSDSLAGALPEEQPEVTDILLDLTRRETHTFSLSFAEKVIGELQGQVNLINNPHRF
HHCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEECCCCCHH
AGFQVLRAPDVPSVLIEIGYLSNPEDEKLISNPEWRKKLADRIALAVKAFAARKRPSNLS
CCEEEEECCCCCEEHHEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GG
CC
>Mature Secondary Structure
MDLQSHYKVGASFQAIRVLFVLLALFCLSLANVPSTFAADSPAPPLSALTFRMAGDDLRT
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEECCCCCCE
RVVVMFDREPKLSTRLFGNPHRLVIDLPETRFGFDEKSLEARGLVSHVRYGLAGKGCSRL
EEEEEECCCCCCCHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
ILTLRGAFDVENLRVLKNENASGYRLVADIVATSDRKFAEKLKEQKGKTGSTERARQQVA
HHHHHCCCCCCHHHEEECCCCCCCEEHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHC
GSALPGNGKPRPFTVMIDPGHGGIDSGAESLSGIKEKNLTLAFGKELRDRLSHERNIKVL
CCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHCHHHCCEEEEHHHHHHHHHCCCCCEEEE
MTREDDTFLRLAERVRLARQHEADLFISIHADTINQHDIRGATVYTISDKASDAVARAMA
EECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHH
ERENKSDSLAGALPEEQPEVTDILLDLTRRETHTFSLSFAEKVIGELQGQVNLINNPHRF
HHCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEECCCCCHH
AGFQVLRAPDVPSVLIEIGYLSNPEDEKLISNPEWRKKLADRIALAVKAFAARKRPSNLS
CCEEEEECCCCCEEHHEECCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]