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The map label for this gene is tig [H]

Identifier: 225852411

GI number: 225852411

Start: 893009

End: 894466

Strand: Direct

Name: tig [H]

Synonym: BMEA_A0938

Alternate gene names: 225852411

Gene position: 893009-894466 (Clockwise)

Preceding gene: 225852410

Following gene: 225852412

Centisome position: 42.01

GC content: 56.24

Gene sequence:

>1458_bases
ATGACAAGAAGTGAAGGTTTGAACATGCAGGTTACCGAAACGCTCAATGAAGGGCTGAAGCGCGAGATCAAAGTCGTGGT
TCCGGCCGGGGATCTTGAAGCCAAGCTCGCTGAGCGGCTCGAAACCGCGCGCGGCCGCGCCCGCATCAACGGCTTCCGTC
CGGGCAAGGTGCCGACGGCTCACCTGCGCAAGATGTACGGCAAGTCCTTCATGGCCGAGATCGTCAACGAAATCCTCAAC
GATTCGTCGCGTTCCATCCTTGCCGAACGCAACGAAAAGTCGGCGACCCAGCCTGAAGTCATCATGTCGGAAGACGAAAA
AGAAGCCGAGAAGGTTCTCGACGGCAAGGCCGATTTCGTTTTCTCGCTGAACTATGAAGTGCTGCCGGCAATCGAGGTCA
AGGACTTCTCCAAGATCGCCGTGACCCGTGAAGTCGTCGACATTTCCGATGAGGAAGTCGATGAACAGGTCAAGCGCATT
GCGTCGTCGACCCGCACCTTTGAAACCAAGAAGGGCAAGGCCGAAAACGAAGATCGCGTCACGATCGACTATCTGGGCAA
GCTCGACGGCGAGCCGTTTGAAGGCGGTGCAGACAATGACGCACAGCTCGTTCTCGGTTCCGGCCAGTTCATTCCGGGCT
TTGAAGAACAGCTCATTGGCTTGAAGGCTGGCGACGAGAAGGTCATCACCGTAACGTTCCCGGCTGAATACGGCGCTGCG
CATCTGGCTGGCAAGGAAGCAACCTTCGACATCAAGGTGAAGGAAGTTGCCAAGCCGAACGAACTCGTTCTCGATGACGA
AACCGCAAAGAAGCTCGGCATTGAGTCGCTTGAGCGTCTGCGTCAGGTTGTGCGCGAACAGATCGAAAGCCAGTACGGCC
AGATCACCCGCCAGAAAGTGAAGCGTCAGATTCTCGACGCCCTTGATGGTGATTATCAGTTTGAAACCCCGCAGAAGCTG
GTTGACGCCGAGTTCAACAACATCTGGCAGCAGATCAACTTCGACCTGCAGCAGGCTGGCCGCACCTTTGAAGACGAGGA
AACGACGGAAGAAGCTGCTCGCGAAGAATATCGCAAGCTTGCAGAACGCCGCGTTCGTCTTGGCCTCGTTCTCTCCGAAA
TCGGCGAGAAGGCAGGCGTGGAAGTGACCGAAGAAGAACTGCAGCGCGCTGTTTACGATCAGGTTCGCCGCTATCCGGGT
CAGGAAAAGGAAATCTACGACTTCCTGCGCCGTACGCCGGATGCCGTCGCCAATCTGCGCGCGCCGATCTTTGAAGAAAA
GGTCGTCGATCATCTGCTGGCCAACATCAATGTGACCGACAAGAAGGTCTCGAAGGAAGAGCTGACGGCTGAAGACGAAG
ATGCAGCTTCGGAAGCAAAGCCTGCCAAGAAGGCGGCTGCGAAGAAGAAGGCTGCGCCGAAGAAGAAGGCCGAAGAAGGC
AAGTCCGAAGAGGCTTGA

Upstream 100 bases:

>100_bases
GGAGACCGTGGGGGTTCGAGTCCCTCCATCCGCACCAACGCCATAAGGCAAAAGAATTTCTCTCCCGCGACAAGGCAGAT
AAACCGGTGACGGCGGGACA

Downstream 100 bases:

>100_bases
TTGGCTTCCTGACGATCAATATGGATGGGCCGCGCGTTGCGCGGCCTTTTCGTTTGCGGACGGACGGCTGAAAAGCTTGC
ATCCACAAGGGCTTTGCTCT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTRSEGLNMQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTAHLRKMYGKSFMAEIVNEILN
DSSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFVFSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRI
ASSTRTFETKKGKAENEDRVTIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAA
HLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQITRQKVKRQILDALDGDYQFETPQKL
VDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKLAERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPG
QEKEIYDFLRRTPDAVANLRAPIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEG
KSEEA

Sequences:

>Translated_485_residues
MTRSEGLNMQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTAHLRKMYGKSFMAEIVNEILN
DSSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFVFSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRI
ASSTRTFETKKGKAENEDRVTIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAA
HLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQITRQKVKRQILDALDGDYQFETPQKL
VDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKLAERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPG
QEKEIYDFLRRTPDAVANLRAPIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEG
KSEEA
>Mature_484_residues
TRSEGLNMQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTAHLRKMYGKSFMAEIVNEILND
SSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFVFSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRIA
SSTRTFETKKGKAENEDRVTIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAAH
LAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQITRQKVKRQILDALDGDYQFETPQKLV
DAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKLAERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPGQ
EKEIYDFLRRTPDAVANLRAPIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEGK
SEEA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=442, Percent_Identity=32.1266968325792, Blast_Score=210, Evalue=2e-55,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 54451; Mature: 54320

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSEGLNMQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTA
CCCCCCCCEEHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCHH
HLRKMYGKSFMAEIVNEILNDSSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHCCCCCEE
FSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRIASSTRTFETKKGKAENEDRV
EEECCCEECCEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
TIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAA
EEEEHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCCCEEEEEEECCHHCCH
HLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQITRQKV
HHCCCCCEEEEEECCCCCCCCEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRQILDALDGDYQFETPQKLVDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHH
AERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPGQEKEIYDFLRRTPDAVANLR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHC
APIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEG
CCHHHHHHHHHHHHCCCCCHHHCCHHHCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHCC
KSEEA
CCCCC
>Mature Secondary Structure 
TRSEGLNMQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTA
CCCCCCCEEHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCHH
HLRKMYGKSFMAEIVNEILNDSSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFV
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHCCCCCEE
FSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRIASSTRTFETKKGKAENEDRV
EEECCCEECCEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
TIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAA
EEEEHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCCCEEEEEEECCHHCCH
HLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQITRQKV
HHCCCCCEEEEEECCCCCCCCEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRQILDALDGDYQFETPQKLVDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHH
AERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPGQEKEIYDFLRRTPDAVANLR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHC
APIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEG
CCHHHHHHHHHHHHCCCCCHHHCCHHHCCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHCC
KSEEA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]