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The map label for this gene is hppA [H]

Identifier: 225852287

GI number: 225852287

Start: 776575

End: 778731

Strand: Direct

Name: hppA [H]

Synonym: BMEA_A0810

Alternate gene names: 225852287

Gene position: 776575-778731 (Clockwise)

Preceding gene: 225852286

Following gene: 225852289

Centisome position: 36.53

GC content: 59.62

Gene sequence:

>2157_bases
ATGCAAATGGGAATGGCAGTCTTGGTTCTCGTCATTGCTTGCGGTGTGCTTTCCGTTCTTTTCGCCATCTGGGCGATCCG
CTCGGTCCTTGCGGCCGATCAGGGAATGCAGCGTATGCAGGAAATTGCTGAAGCCATCCGCGAGGGTGCGTCAGCCTATC
TCACACGACAATATTCAACGATTGCCATCGTGGGCATCGTGGTCTTCCTGCTGGCCTGGTATCTGTTGTCGCTCAATGCC
GCAATGGGCTTCCTGATTGGCGCGGTTCTGTCGGGTGTCACAGGTTTCATCGGAATGCATGTTTCGGTTCGCGCCAATGT
GCGCACCGCGCAGGCAGCGTCTCTGAGCCTTGCAGGCGGGCTGGAGCTGGCTTTCAAGTCTGGCGCCATCACCGGGCTTC
TGGTGGCTGGCCTGGCGCTGCTTGGCGTCTCGGTCTATTATTTCGTGCTGACCGTCTGGCTGGGTTATGCGCCCGCCGAC
CGCACCGTGATCGACTCGCTCGTATCGCTCGGCTTTGGCGCTTCGCTGATCTCCATTTTCGCCCGTCTTGGCGGCGGCAT
CTTCACCAAGGGTGCCGATGTGGGCGGCGATCTCGTCGGCAAGGTGGAAGCAGGAATTCCGGAGGACGATCCGCGCAATC
CCGCAACCATTGCGGACAATGTGGGCGACAATGTAGGCGATTGCGCTGGCATGGCTGCCGACCTGTTCGAGACCTATGCC
GTCACCGTGGTTGCGACGATGGTTCTGGGAGCGATCTTCTTCCACGGTTCCGACGCGTTGACCAATGTGATGCTCTATCC
GCTGATGATCTGCGGTGCGTGCGTGATAACCTCGATAGCGGGTACCTTCTTCGTCAAGCTTGGCGTGAACGGCTCCATTA
TGGGCGCGCTCTACAAGGGGCTGATTGCAACGGGGCTGCTTTCCATCGTCGGGCTTGGCGTTGCCAATACGCTGACCGTC
GGATGGGGCGAGATCGGAACCGTGGCTGGCAAGAGCATCACTGGCACCAATCTTTTCGTCTGCGGACTGATCGGCCTGAT
TGTGACCGGCCTGATCGTGGTGATTACCGAATATTATACCGGCACCAACAAACGCCCGGTCAATTCCATCGCGCAAGCCT
CGGTGACGGGCCACGGCACCAATGTCATTCAGGGGCTTGCGGTTTCGCTTGAATCCACCGCCCTGCCTGCCATCGTGATT
GTTGGTGGCATCATCTCGACTTACCAGCTTGCGGGCCTGTTCGGCACGGCCATTGCCGTTACGGCCATGCTCGGCATTGC
GGGCATGATCGTGGCGCTCGATGCGTTCGGGCCGGTTACGGACAATGCGGGCGGCATTGCCGAAATGGCCGGGCTCGACC
CTGAGGTGCGTAAGGCCACCGATGCGCTCGATGCCGTTGGCAACACCACAAAGGCCGTCACCAAGGGCTATGCCATCGGT
TCGGCCGGTCTCGGCGCGCTGGTGCTTTTCGCGGCCTATTCCAACGATCTGGCCTATTTTGCCGCCAATGGGCAAATCTA
TCCGTATTTTGCCGATATGGGGCCTGTCTCCTTCGATCTCTCCAACCCTTATGTGGTTGCGGGGCTGATCTTCGGCGGCC
TGATCCCCTATCTTTTTGGCGGCATGGCCATGACGGCTGTGGGCCGGGCAGGCGGCGCGGTGGTGCAGGAAGTGCGCCGC
CAGTTCCGTGAGAAGCCCGGTATCATGACGGGCAAGGAGCGCCCGGATTATGCGCGCGCGGTCGATCTTCTGACCAAGGC
GGCCATCCGCGAGATGATTATCCCTTCACTCCTGCCGGTGCTGGCGCCGATTGTCGTCTATTTCGGCGTGTTGCTTATCT
CCGGCTCGAAGGCTGCGGCCTTTGCCGCACTTGGCGCTTCACTTCTCGGCGTTATCATCAATGGGCTTTTCGTGGCGATT
TCCATGACCTCCGGCGGCGGTGCATGGGATAATGCCAAGAAAAGCTTCGAGGATGGTTTTACCGATGCCGATGGAGTAAA
GCATATGAAGGGCTCGGAAGCGCACAAGGCTTCCGTCACGGGCGATACGGTAGGGGATCCCTATAAGGATACGGCAGGCC
CTGCCGTTAACCCGGCCATCAAGATCACCAATATCGTGGCGCTTCTTCTGCTGGCCGTGCTGGCCCACATGGCCTGA

Upstream 100 bases:

>100_bases
GTTTGCACCGGGTCGGCGCTCCGATTGTCTGGTTGGCCGCGCATTTTTCCCGAAAACCGTTTCACACTTTTCGGAATGCG
CTCAATGGGAGTTGGCCTTT

Downstream 100 bases:

>100_bases
TCTTTTCTCTTGTGTATAAAACAGAAAACCCGCCGTGAAGGCGGGTTTTCCTTGATTTCCATCGGGCCGATTTATGAACC
GCCTGCCGATGGCAGAGAAG

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MQMGMAVLVLVIACGVLSVLFAIWAIRSVLAADQGMQRMQEIAEAIREGASAYLTRQYSTIAIVGIVVFLLAWYLLSLNA
AMGFLIGAVLSGVTGFIGMHVSVRANVRTAQAASLSLAGGLELAFKSGAITGLLVAGLALLGVSVYYFVLTVWLGYAPAD
RTVIDSLVSLGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYA
VTVVATMVLGAIFFHGSDALTNVMLYPLMICGACVITSIAGTFFVKLGVNGSIMGALYKGLIATGLLSIVGLGVANTLTV
GWGEIGTVAGKSITGTNLFVCGLIGLIVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVI
VGGIISTYQLAGLFGTAIAVTAMLGIAGMIVALDAFGPVTDNAGGIAEMAGLDPEVRKATDALDAVGNTTKAVTKGYAIG
SAGLGALVLFAAYSNDLAYFAANGQIYPYFADMGPVSFDLSNPYVVAGLIFGGLIPYLFGGMAMTAVGRAGGAVVQEVRR
QFREKPGIMTGKERPDYARAVDLLTKAAIREMIIPSLLPVLAPIVVYFGVLLISGSKAAAFAALGASLLGVIINGLFVAI
SMTSGGGAWDNAKKSFEDGFTDADGVKHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHMA

Sequences:

>Translated_718_residues
MQMGMAVLVLVIACGVLSVLFAIWAIRSVLAADQGMQRMQEIAEAIREGASAYLTRQYSTIAIVGIVVFLLAWYLLSLNA
AMGFLIGAVLSGVTGFIGMHVSVRANVRTAQAASLSLAGGLELAFKSGAITGLLVAGLALLGVSVYYFVLTVWLGYAPAD
RTVIDSLVSLGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYA
VTVVATMVLGAIFFHGSDALTNVMLYPLMICGACVITSIAGTFFVKLGVNGSIMGALYKGLIATGLLSIVGLGVANTLTV
GWGEIGTVAGKSITGTNLFVCGLIGLIVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVI
VGGIISTYQLAGLFGTAIAVTAMLGIAGMIVALDAFGPVTDNAGGIAEMAGLDPEVRKATDALDAVGNTTKAVTKGYAIG
SAGLGALVLFAAYSNDLAYFAANGQIYPYFADMGPVSFDLSNPYVVAGLIFGGLIPYLFGGMAMTAVGRAGGAVVQEVRR
QFREKPGIMTGKERPDYARAVDLLTKAAIREMIIPSLLPVLAPIVVYFGVLLISGSKAAAFAALGASLLGVIINGLFVAI
SMTSGGGAWDNAKKSFEDGFTDADGVKHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHMA
>Mature_718_residues
MQMGMAVLVLVIACGVLSVLFAIWAIRSVLAADQGMQRMQEIAEAIREGASAYLTRQYSTIAIVGIVVFLLAWYLLSLNA
AMGFLIGAVLSGVTGFIGMHVSVRANVRTAQAASLSLAGGLELAFKSGAITGLLVAGLALLGVSVYYFVLTVWLGYAPAD
RTVIDSLVSLGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYA
VTVVATMVLGAIFFHGSDALTNVMLYPLMICGACVITSIAGTFFVKLGVNGSIMGALYKGLIATGLLSIVGLGVANTLTV
GWGEIGTVAGKSITGTNLFVCGLIGLIVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVI
VGGIISTYQLAGLFGTAIAVTAMLGIAGMIVALDAFGPVTDNAGGIAEMAGLDPEVRKATDALDAVGNTTKAVTKGYAIG
SAGLGALVLFAAYSNDLAYFAANGQIYPYFADMGPVSFDLSNPYVVAGLIFGGLIPYLFGGMAMTAVGRAGGAVVQEVRR
QFREKPGIMTGKERPDYARAVDLLTKAAIREMIIPSLLPVLAPIVVYFGVLLISGSKAAAFAALGASLLGVIINGLFVAI
SMTSGGGAWDNAKKSFEDGFTDADGVKHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHMA

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 73372; Mature: 73372

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMGMAVLVLVIACGVLSVLFAIWAIRSVLAADQGMQRMQEIAEAIREGASAYLTRQYST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIVGIVVFLLAWYLLSLNAAMGFLIGAVLSGVTGFIGMHVSVRANVRTAQAASLSLAGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHCCC
LELAFKSGAITGLLVAGLALLGVSVYYFVLTVWLGYAPADRTVIDSLVSLGFGASLISIF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHH
ARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYA
HHHCCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
VTVVATMVLGAIFFHGSDALTNVMLYPLMICGACVITSIAGTFFVKLGVNGSIMGALYKG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
LIATGLLSIVGLGVANTLTVGWGEIGTVAGKSITGTNLFVCGLIGLIVTGLIVVITEYYT
HHHHHHHHHHHHCHHHHEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVIVGGIISTYQLAGLFGTAIAV
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TAMLGIAGMIVALDAFGPVTDNAGGIAEMAGLDPEVRKATDALDAVGNTTKAVTKGYAIG
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCC
SAGLGALVLFAAYSNDLAYFAANGQIYPYFADMGPVSFDLSNPYVVAGLIFGGLIPYLFG
CCHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHH
GMAMTAVGRAGGAVVQEVRRQFREKPGIMTGKERPDYARAVDLLTKAAIREMIIPSLLPV
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPIVVYFGVLLISGSKAAAFAALGASLLGVIINGLFVAISMTSGGGAWDNAKKSFEDGF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCCC
TDADGVKHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHMA
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQMGMAVLVLVIACGVLSVLFAIWAIRSVLAADQGMQRMQEIAEAIREGASAYLTRQYST
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAIVGIVVFLLAWYLLSLNAAMGFLIGAVLSGVTGFIGMHVSVRANVRTAQAASLSLAGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHCCC
LELAFKSGAITGLLVAGLALLGVSVYYFVLTVWLGYAPADRTVIDSLVSLGFGASLISIF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHH
ARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYA
HHHCCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
VTVVATMVLGAIFFHGSDALTNVMLYPLMICGACVITSIAGTFFVKLGVNGSIMGALYKG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
LIATGLLSIVGLGVANTLTVGWGEIGTVAGKSITGTNLFVCGLIGLIVTGLIVVITEYYT
HHHHHHHHHHHHCHHHHEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVIVGGIISTYQLAGLFGTAIAV
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TAMLGIAGMIVALDAFGPVTDNAGGIAEMAGLDPEVRKATDALDAVGNTTKAVTKGYAIG
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCCCC
SAGLGALVLFAAYSNDLAYFAANGQIYPYFADMGPVSFDLSNPYVVAGLIFGGLIPYLFG
CCHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHH
GMAMTAVGRAGGAVVQEVRRQFREKPGIMTGKERPDYARAVDLLTKAAIREMIIPSLLPV
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAPIVVYFGVLLISGSKAAAFAALGASLLGVIINGLFVAISMTSGGGAWDNAKKSFEDGF
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHCCC
TDADGVKHMKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHMA
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]