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The map label for this gene is ribE [H]

Identifier: 225852284

GI number: 225852284

Start: 774439

End: 775047

Strand: Direct

Name: ribE [H]

Synonym: BMEA_A0807

Alternate gene names: 225852284

Gene position: 774439-775047 (Clockwise)

Preceding gene: 225852283

Following gene: 225852285

Centisome position: 36.43

GC content: 57.14

Gene sequence:

>609_bases
ATGTTTACAGGCATAATCACCGATATCGGCAAGGTTGACCGGGTCAAGCCGTTGAATGAAGGCGTCCTTTTGCGGATTGA
AACCGCCTACGATCCTGAAACGATCGAGCTTGGCGCATCGATCGCCTGTTCCGGCGTATGCCTCACGGTTGTTGCGCTGC
CGGAAAAGGGCAGCAATGCCCGCTGGTTCGAGGTGGAGGCATGGGAAGAGGCGCTGCGGCTGACCACAATCTCCAGTTGG
CAAAGCGGCAGGAAGATCAATCTGGAACGTTCGCTGAAACTTGGCGATGAAATGGGTGGTCATCTTGTTTTCGGCCATGT
TGACGGACAGACCGAAATCGTCGAGCGCAAGGATGAGGGCGACGCCGTGCGCTTCACCCTGCGCGCGCCGGAAGAACTGG
CGCCTTTCATCGCGCAGAAGGGGTCTGTCGCGCTTGACGGAACTTCGCTCACGGTCAATGGCGTCAACGCAAACGAGTTC
GATGTACTCCTGATCCGCCATTCGCTGGAAGTCACCACATGGGGCGAGCGCAAAGCGGGCGACAAGGTCAATATCGAGAT
CGACCAGCTCGCGCGTTATGCGGCAAGGCTTGCGCAATATCAGAAATAG

Upstream 100 bases:

>100_bases
CCGTTGAGGGACTGGAAACCCATATCGCAAGCGAATTCAAAATTCTGAGGCGGATGCGTTACGCAGATGATGCCTGTGCG
GAATATGTAAGGAACACGTG

Downstream 100 bases:

>100_bases
GCTTAGAGCCTACGAATGAAGCTGTAACAGCATTTCCCTATTTTAAGCGTTGACCGCAGCCCTTGCGATCCGCGATTTTC
TCATGGAGTTTCTCATGTCC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNARWFEVEAWEEALRLTTISSW
QSGRKINLERSLKLGDEMGGHLVFGHVDGQTEIVERKDEGDAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEF
DVLLIRHSLEVTTWGERKAGDKVNIEIDQLARYAARLAQYQK

Sequences:

>Translated_202_residues
MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNARWFEVEAWEEALRLTTISSW
QSGRKINLERSLKLGDEMGGHLVFGHVDGQTEIVERKDEGDAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEF
DVLLIRHSLEVTTWGERKAGDKVNIEIDQLARYAARLAQYQK
>Mature_202_residues
MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNARWFEVEAWEEALRLTTISSW
QSGRKINLERSLKLGDEMGGHLVFGHVDGQTEIVERKDEGDAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEF
DVLLIRHSLEVTTWGERKAGDKVNIEIDQLARYAARLAQYQK

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=194, Percent_Identity=34.5360824742268, Blast_Score=100, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319733, Length=200, Percent_Identity=35, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22254; Mature: 22254

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNA
CCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCEEECCEEEEEEEECCCCCCC
RWFEVEAWEEALRLTTISSWQSGRKINLERSLKLGDEMGGHLVFGHVDGQTEIVERKDEG
EEEEHHHHHHHHHEEEECCCCCCCEECHHHCEECCCCCCCEEEEEEECCCEEEEEECCCC
DAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEFDVLLIRHSLEVTTWGERKAG
CEEEEEEECCHHHHHHHHCCCCEEECCCEEEEECCCCCCEEEEEEEEEEEEEECCCCCCC
DKVNIEIDQLARYAARLAQYQK
CEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNA
CCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCEEECCEEEEEEEECCCCCCC
RWFEVEAWEEALRLTTISSWQSGRKINLERSLKLGDEMGGHLVFGHVDGQTEIVERKDEG
EEEEHHHHHHHHHEEEECCCCCCCEECHHHCEECCCCCCCEEEEEEECCCEEEEEECCCC
DAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEFDVLLIRHSLEVTTWGERKAG
CEEEEEEECCHHHHHHHHCCCCEEECCCEEEEECCCCCCEEEEEEEEEEEEEECCCCCCC
DKVNIEIDQLARYAARLAQYQK
CEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]