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The map label for this gene is ribD [H]

Identifier: 225852283

GI number: 225852283

Start: 773318

End: 774439

Strand: Direct

Name: ribD [H]

Synonym: BMEA_A0806

Alternate gene names: 225852283

Gene position: 773318-774439 (Clockwise)

Preceding gene: 225852282

Following gene: 225852284

Centisome position: 36.38

GC content: 61.85

Gene sequence:

>1122_bases
ATGGGCGCCAGCGAATTTCCGCGTTCAAAAGCGACATTGAATGATCTGCGCTTCATGGAAGCGACGATCCGTTATGCGCG
CCGTCACAAGGGGCTGACTGGCACCAATCCTTCGGTCGGCACGATTATCGTCAAGGACGGTGTCATTGTCGGGCGCGGCG
TGACGGCATTGGGCGGAAGGCCCCATGCCGAGCCGCAGGCTTTGGCTGAAGTGGGTGAGGCGGCGCGAGGGGCGACGGCC
TATGTGACGCTGGAGCCCTGCGCGCATCATGGGCGCACACCGCCTTGCGCGGAGGCGCTGGTGCGCTCGGGCGTCGCGCG
TGTCGTGGTTGCCGCAACCGATCCGGACGAGCGTGTCAGCGGAAAAGGCTTTGCCATTCTGCGCGAAGCGGGCATTGAAG
TCGTGCCGGGCATTTTGTCCGAACAGGCTGCCGACGACCTTGCGGGCTATCTGAATCGATCTGCGAGGAAACGCCCGGAA
GTGATTCTGAAACTTGCGCTTTCTGCCGATGGCATGATCGGCCGGAAAGGTGCGGGGCAGGTGGCTATCACCGGCCCAGT
TTCGCGCGCGCAGTCACATATTCTGCGCGCACAGGCCGATATTATCCTGATCGGTATCGAAACAGCCCTTGCCGATGATC
CGGTTTTGAATTGCCGTCTGCCGGGGCTGGAACAGCGTTCGCCCGTTCGTGTCGTGCTGGATGGCGGGTTGCGTCTGCCG
CTTTCCTCAAGGCTGGTGCGCTCTGCCGATACGCAGCCCCTGTGGGTTGCCTGCGGGGAGGAAGCCCCTGACGAGCGCCG
CGCCGCGCTGGGTGCTGCGGGCTGCCGTATCCTTGCAACCGAGACGCATGATGGCCGCATCGCCCTGCCGGAATTGCTGG
ATGATCTTGCCGCGCAGGGCATTGCTTCTGTTCTCGTTGAGGGCGGGGCGGGCGTCGCCAAAAGCTTTCTGGATGAAAAA
CTCGTGGACCGGCTGATCATCTTCCGTTCGCCATTGGTGATCGGCGCGGCGGATGGGGTTGCCGTTGAGGGACTGGAAAC
CCATATCGCAAGCGAATTCAAAATTCTGAGGCGGATGCGTTACGCAGATGATGCCTGTGCGGAATATGTAAGGAACACGT
GA

Upstream 100 bases:

>100_bases
TTCGCTTCCGTTTATCGCAATTTCAGCAAGGCGGTGGATTTCCACAATGTCATCGATGAGCTGACGGTTTCCGAGACCGG
CGATAATCTGGAAACGTAGA

Downstream 100 bases:

>100_bases
TGTTTACAGGCATAATCACCGATATCGGCAAGGTTGACCGGGTCAAGCCGTTGAATGAAGGCGTCCTTTTGCGGATTGAA
ACCGCCTACGATCCTGAAAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MGASEFPRSKATLNDLRFMEATIRYARRHKGLTGTNPSVGTIIVKDGVIVGRGVTALGGRPHAEPQALAEVGEAARGATA
YVTLEPCAHHGRTPPCAEALVRSGVARVVVAATDPDERVSGKGFAILREAGIEVVPGILSEQAADDLAGYLNRSARKRPE
VILKLALSADGMIGRKGAGQVAITGPVSRAQSHILRAQADIILIGIETALADDPVLNCRLPGLEQRSPVRVVLDGGLRLP
LSSRLVRSADTQPLWVACGEEAPDERRAALGAAGCRILATETHDGRIALPELLDDLAAQGIASVLVEGGAGVAKSFLDEK
LVDRLIIFRSPLVIGAADGVAVEGLETHIASEFKILRRMRYADDACAEYVRNT

Sequences:

>Translated_373_residues
MGASEFPRSKATLNDLRFMEATIRYARRHKGLTGTNPSVGTIIVKDGVIVGRGVTALGGRPHAEPQALAEVGEAARGATA
YVTLEPCAHHGRTPPCAEALVRSGVARVVVAATDPDERVSGKGFAILREAGIEVVPGILSEQAADDLAGYLNRSARKRPE
VILKLALSADGMIGRKGAGQVAITGPVSRAQSHILRAQADIILIGIETALADDPVLNCRLPGLEQRSPVRVVLDGGLRLP
LSSRLVRSADTQPLWVACGEEAPDERRAALGAAGCRILATETHDGRIALPELLDDLAAQGIASVLVEGGAGVAKSFLDEK
LVDRLIIFRSPLVIGAADGVAVEGLETHIASEFKILRRMRYADDACAEYVRNT
>Mature_372_residues
GASEFPRSKATLNDLRFMEATIRYARRHKGLTGTNPSVGTIIVKDGVIVGRGVTALGGRPHAEPQALAEVGEAARGATAY
VTLEPCAHHGRTPPCAEALVRSGVARVVVAATDPDERVSGKGFAILREAGIEVVPGILSEQAADDLAGYLNRSARKRPEV
ILKLALSADGMIGRKGAGQVAITGPVSRAQSHILRAQADIILIGIETALADDPVLNCRLPGLEQRSPVRVVLDGGLRLPL
SSRLVRSADTQPLWVACGEEAPDERRAALGAAGCRILATETHDGRIALPELLDDLAAQGIASVLVEGGAGVAKSFLDEKL
VDRLIIFRSPLVIGAADGVAVEGLETHIASEFKILRRMRYADDACAEYVRNT

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=374, Percent_Identity=38.2352941176471, Blast_Score=221, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39322; Mature: 39190

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASEFPRSKATLNDLRFMEATIRYARRHKGLTGTNPSVGTIIVKDGVIVGRGVTALGGR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCC
PHAEPQALAEVGEAARGATAYVTLEPCAHHGRTPPCAEALVRSGVARVVVAATDPDERVS
CCCCHHHHHHHHHHCCCCEEEEEECCHHHCCCCCHHHHHHHHCCCEEEEEEECCCCHHCC
GKGFAILREAGIEVVPGILSEQAADDLAGYLNRSARKRPEVILKLALSADGMIGRKGAGQ
CCCEEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHCCCCCCCCCCCCC
VAITGPVSRAQSHILRAQADIILIGIETALADDPVLNCRLPGLEQRSPVRVVLDGGLRLP
EEEECCHHHHHHHHHHHCCCEEEEEEHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCC
LSSRLVRSADTQPLWVACGEEAPDERRAALGAAGCRILATETHDGRIALPELLDDLAAQG
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCEEHHHHHHHHHHHH
IASVLVEGGAGVAKSFLDEKLVDRLIIFRSPLVIGAADGVAVEGLETHIASEFKILRRMR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECHHHHHHHHHHHHHHHHH
YADDACAEYVRNT
CCHHHHHHHHHCC
>Mature Secondary Structure 
GASEFPRSKATLNDLRFMEATIRYARRHKGLTGTNPSVGTIIVKDGVIVGRGVTALGGR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCEEEECCCCCCCCC
PHAEPQALAEVGEAARGATAYVTLEPCAHHGRTPPCAEALVRSGVARVVVAATDPDERVS
CCCCHHHHHHHHHHCCCCEEEEEECCHHHCCCCCHHHHHHHHCCCEEEEEEECCCCHHCC
GKGFAILREAGIEVVPGILSEQAADDLAGYLNRSARKRPEVILKLALSADGMIGRKGAGQ
CCCEEEEECCCCHHHCHHHHHHHHHHHHHHHHHHHCCCHHHEEEEHHCCCCCCCCCCCCC
VAITGPVSRAQSHILRAQADIILIGIETALADDPVLNCRLPGLEQRSPVRVVLDGGLRLP
EEEECCHHHHHHHHHHHCCCEEEEEEHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCCC
LSSRLVRSADTQPLWVACGEEAPDERRAALGAAGCRILATETHDGRIALPELLDDLAAQG
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEEEECCCCCEEHHHHHHHHHHHH
IASVLVEGGAGVAKSFLDEKLVDRLIIFRSPLVIGAADGVAVEGLETHIASEFKILRRMR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECHHHHHHHHHHHHHHHHH
YADDACAEYVRNT
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]