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The map label for this gene is nlpI [C]

Identifier: 225851938

GI number: 225851938

Start: 425976

End: 427841

Strand: Direct

Name: nlpI [C]

Synonym: BMEA_A0433

Alternate gene names: 225851938

Gene position: 425976-427841 (Clockwise)

Preceding gene: 225851937

Following gene: 225851939

Centisome position: 20.04

GC content: 59.11

Gene sequence:

>1866_bases
ATGCGGCTAGGATCGAAACATCGCCCGCTTTATGGATTGCTGCTCTCGCTTCTGGCGGGCATCGCAATTTCGACGAGCGG
AGCATTGGCCAAGACCACACCCGATCCCGTTCGCGCGCAGGTCCGCGCCGGATCCTTCGCGGGCGCTTATCTTGCGGGCC
GCACGGCTGAATCCGACGACAACCTTTCCGCTGCCGTGGATTTCTATCGTCAGGCCATGGCTTTCGATCCGAACAACAGC
CAGATCAAGCAGGACCTGATGCTGGTTCTGCTGACCGAAGGCCGTTTCAAGGATGCGTTGCCGCTTGCCCATGAATTGCA
GAATGTGACGGCCATCGAGCGGTTTTCTCGGCTGGCACTGGCCATTGATGCGATCAACCGCCAGCAATATCGCAAGGTCG
GCCCGCTTCTCATGTTCTCGCTCCAGTCGGACATGGACCGGCTGTTGATCAATTTGATGAATGCCTGGGTGAAGGTCGGG
CAGGGCAATCCGAAAGAGGCGCTGGCCGATGTGCAGAAAATGGATGGGCCGGAATGGTACGATCTTTTCCGCACCTATAA
TGCCGCGTTGATTGCCGATCTTGCAGGCCGCAAGCAGGAAGCGCGGGACTATTACCAGCAGGCCATCGACGACCGCCGCG
GCGGCAGCGCCGCGCCCGACACTTATGAGCGCGTGGTCATGGCCTTTGCCGCGTTCAAGCTGCGCCAGGGCGACAGGGCA
GGTGCGATCAAGACGCTGAAGGATGCCGAAGAGCTTCTGAATGGCCGCATGACCATCACTGAAATGCGCGAGAAGATCGA
GGCGGGCCACAAATATGGCCGCTTGGTCAAGACCGCGCAGGACGGGGCCGCCGAAACGCTCTATACGCTGGGCACAGCCA
TCAACCGCAGCGGTGCGGAAGCTTTCGCTAAGCTCTATCTCCAGATGTCGCTGCCGCTTCGCCCGGATAACGACGCCACG
CTCTACCAGCTTGGCGATATTTCGGCAAAGTTGCACGAGCCGCAAAAGGCCGTCGAATATTATGGCCGCGTGCCGGAACA
ATCGCCCTATCGCCGCGATGCGGAAATGCAGCGCGCGCTCAATCTGGCGGAAAACGACCAGTCGGCGGAAGCCATCAAGC
AGTTGAAAGTCCTGCTTGGCCGCGACAAGTCCGACATGCGCACCTATCTGGCGCTGGGCGGCGTTTATGCGCAGGACAAG
AATTTTGCGGATGCGGCAAAGATTTACGATGCGGCGGTCGAGCAGATCAAGACGCCGGCACGCAAGGATTGGCCACTCTT
CTATCAGCGCGGCATCGCCTATGAACGGCTACAGGAATGGGACAAGGCGGAGCCCAATTTCCGCAAGGCGCTGGAGCTTT
ATCCCGATCAGCCGCAGGTTCTGAACTATCTTGGTTATTCCTGGGTGGACCGGAACGAAAACCTCGATGAAGCCCTGAAC
ATGATCAGGAAAGCGGTCGAGTTGCGCCCGCAGGACGGCTATATCGTTGATTCGCTTGGCTGGGCCTATTACCAGCTTGG
CCGTTATAACGACGCTGTGGTCGAACTGGAAAAGGCCGTGAAGCTGCGCCCGGAAGACCCGACCATCAACGACCATATGG
GCGATGCCTATTGGCGGGTCGGTCGTCTGCTTGAAGCAACCTTCCAGTGGAACCATGCCATTGCGGGCAAGCCGGAACCG
GAAGAACTGGCGAAAATCAAGGAAAAGCTGAAGAAGGGCCTGCCGGATATTCCGGGCCAGTCGGCTGCCGATGCAACAAA
GCCTGCCGGGAAAAAGCCAGATGAGGCAAAGCCGGAAGCGCCTGCTCCATCGGCCACGCCGGCTGCACCTTCCGACAAGG
CCCCGGAAAAGCCGACAACCGATTGA

Upstream 100 bases:

>100_bases
ATTTTGCGCCGGATGATGCGACAAAACAAAGAGTTGGAGCGGTTCTGCCGATTGTGTTGAAACAGGAAGCGCTCCAGGGA
ACTGAAAAGGATAGGGCTTT

Downstream 100 bases:

>100_bases
ACGCATTTACAAGGGGGGCCGCTTCATTCTGGGCCGCGTGCTGATGCAATAGCGGCACAGTGCACGCTTGACCCTGCCTT
GCTGACAAATTAGACCGGGC

Product: tetratricopeptide repeat protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MRLGSKHRPLYGLLLSLLAGIAISTSGALAKTTPDPVRAQVRAGSFAGAYLAGRTAESDDNLSAAVDFYRQAMAFDPNNS
QIKQDLMLVLLTEGRFKDALPLAHELQNVTAIERFSRLALAIDAINRQQYRKVGPLLMFSLQSDMDRLLINLMNAWVKVG
QGNPKEALADVQKMDGPEWYDLFRTYNAALIADLAGRKQEARDYYQQAIDDRRGGSAAPDTYERVVMAFAAFKLRQGDRA
GAIKTLKDAEELLNGRMTITEMREKIEAGHKYGRLVKTAQDGAAETLYTLGTAINRSGAEAFAKLYLQMSLPLRPDNDAT
LYQLGDISAKLHEPQKAVEYYGRVPEQSPYRRDAEMQRALNLAENDQSAEAIKQLKVLLGRDKSDMRTYLALGGVYAQDK
NFADAAKIYDAAVEQIKTPARKDWPLFYQRGIAYERLQEWDKAEPNFRKALELYPDQPQVLNYLGYSWVDRNENLDEALN
MIRKAVELRPQDGYIVDSLGWAYYQLGRYNDAVVELEKAVKLRPEDPTINDHMGDAYWRVGRLLEATFQWNHAIAGKPEP
EELAKIKEKLKKGLPDIPGQSAADATKPAGKKPDEAKPEAPAPSATPAAPSDKAPEKPTTD

Sequences:

>Translated_621_residues
MRLGSKHRPLYGLLLSLLAGIAISTSGALAKTTPDPVRAQVRAGSFAGAYLAGRTAESDDNLSAAVDFYRQAMAFDPNNS
QIKQDLMLVLLTEGRFKDALPLAHELQNVTAIERFSRLALAIDAINRQQYRKVGPLLMFSLQSDMDRLLINLMNAWVKVG
QGNPKEALADVQKMDGPEWYDLFRTYNAALIADLAGRKQEARDYYQQAIDDRRGGSAAPDTYERVVMAFAAFKLRQGDRA
GAIKTLKDAEELLNGRMTITEMREKIEAGHKYGRLVKTAQDGAAETLYTLGTAINRSGAEAFAKLYLQMSLPLRPDNDAT
LYQLGDISAKLHEPQKAVEYYGRVPEQSPYRRDAEMQRALNLAENDQSAEAIKQLKVLLGRDKSDMRTYLALGGVYAQDK
NFADAAKIYDAAVEQIKTPARKDWPLFYQRGIAYERLQEWDKAEPNFRKALELYPDQPQVLNYLGYSWVDRNENLDEALN
MIRKAVELRPQDGYIVDSLGWAYYQLGRYNDAVVELEKAVKLRPEDPTINDHMGDAYWRVGRLLEATFQWNHAIAGKPEP
EELAKIKEKLKKGLPDIPGQSAADATKPAGKKPDEAKPEAPAPSATPAAPSDKAPEKPTTD
>Mature_621_residues
MRLGSKHRPLYGLLLSLLAGIAISTSGALAKTTPDPVRAQVRAGSFAGAYLAGRTAESDDNLSAAVDFYRQAMAFDPNNS
QIKQDLMLVLLTEGRFKDALPLAHELQNVTAIERFSRLALAIDAINRQQYRKVGPLLMFSLQSDMDRLLINLMNAWVKVG
QGNPKEALADVQKMDGPEWYDLFRTYNAALIADLAGRKQEARDYYQQAIDDRRGGSAAPDTYERVVMAFAAFKLRQGDRA
GAIKTLKDAEELLNGRMTITEMREKIEAGHKYGRLVKTAQDGAAETLYTLGTAINRSGAEAFAKLYLQMSLPLRPDNDAT
LYQLGDISAKLHEPQKAVEYYGRVPEQSPYRRDAEMQRALNLAENDQSAEAIKQLKVLLGRDKSDMRTYLALGGVYAQDK
NFADAAKIYDAAVEQIKTPARKDWPLFYQRGIAYERLQEWDKAEPNFRKALELYPDQPQVLNYLGYSWVDRNENLDEALN
MIRKAVELRPQDGYIVDSLGWAYYQLGRYNDAVVELEKAVKLRPEDPTINDHMGDAYWRVGRLLEATFQWNHAIAGKPEP
EELAKIKEKLKKGLPDIPGQSAADATKPAGKKPDEAKPEAPAPSATPAAPSDKAPEKPTTD

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Drosophila melanogaster, GI161076610, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920486, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF07719 TPR_2; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 69317; Mature: 69317

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGSKHRPLYGLLLSLLAGIAISTSGALAKTTPDPVRAQVRAGSFAGAYLAGRTAESDD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHCCCCCCCCC
NLSAAVDFYRQAMAFDPNNSQIKQDLMLVLLTEGRFKDALPLAHELQNVTAIERFSRLAL
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIDAINRQQYRKVGPLLMFSLQSDMDRLLINLMNAWVKVGQGNPKEALADVQKMDGPEWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHH
DLFRTYNAALIADLAGRKQEARDYYQQAIDDRRGGSAAPDTYERVVMAFAAFKLRQGDRA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GAIKTLKDAEELLNGRMTITEMREKIEAGHKYGRLVKTAQDGAAETLYTLGTAINRSGAE
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
AFAKLYLQMSLPLRPDNDATLYQLGDISAKLHEPQKAVEYYGRVPEQSPYRRDAEMQRAL
HHHHHHHHHCCCCCCCCCCCEEEECCCHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHH
NLAENDQSAEAIKQLKVLLGRDKSDMRTYLALGGVYAQDKNFADAAKIYDAAVEQIKTPA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCC
RKDWPLFYQRGIAYERLQEWDKAEPNFRKALELYPDQPQVLNYLGYSWVDRNENLDEALN
CCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHCCHHHCCCCCHHHHHH
MIRKAVELRPQDGYIVDSLGWAYYQLGRYNDAVVELEKAVKLRPEDPTINDHMGDAYWRV
HHHHHHHCCCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
GRLLEATFQWNHAIAGKPEPEELAKIKEKLKKGLPDIPGQSAADATKPAGKKPDEAKPEA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAPSATPAAPSDKAPEKPTTD
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLGSKHRPLYGLLLSLLAGIAISTSGALAKTTPDPVRAQVRAGSFAGAYLAGRTAESDD
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCHHHCCCCCCCCC
NLSAAVDFYRQAMAFDPNNSQIKQDLMLVLLTEGRFKDALPLAHELQNVTAIERFSRLAL
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIDAINRQQYRKVGPLLMFSLQSDMDRLLINLMNAWVKVGQGNPKEALADVQKMDGPEWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHH
DLFRTYNAALIADLAGRKQEARDYYQQAIDDRRGGSAAPDTYERVVMAFAAFKLRQGDRA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
GAIKTLKDAEELLNGRMTITEMREKIEAGHKYGRLVKTAQDGAAETLYTLGTAINRSGAE
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
AFAKLYLQMSLPLRPDNDATLYQLGDISAKLHEPQKAVEYYGRVPEQSPYRRDAEMQRAL
HHHHHHHHHCCCCCCCCCCCEEEECCCHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHH
NLAENDQSAEAIKQLKVLLGRDKSDMRTYLALGGVYAQDKNFADAAKIYDAAVEQIKTPA
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCC
RKDWPLFYQRGIAYERLQEWDKAEPNFRKALELYPDQPQVLNYLGYSWVDRNENLDEALN
CCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHCCHHHCCCCCHHHHHH
MIRKAVELRPQDGYIVDSLGWAYYQLGRYNDAVVELEKAVKLRPEDPTINDHMGDAYWRV
HHHHHHHCCCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
GRLLEATFQWNHAIAGKPEPEELAKIKEKLKKGLPDIPGQSAADATKPAGKKPDEAKPEA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAPSATPAAPSDKAPEKPTTD
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7883699; 10984043 [H]